Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells Y Liu, PK Li, C Li, J Lin Journal of Biological Chemistry 285 (35), 27429-27439, 2010 | 186 | 2010 |
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030 L Lin, Y Liu, H Li, PK Li, J Fuchs, H Shibata, Y Iwabuchi, J Lin British journal of cancer 105 (2), 212-220, 2011 | 182 | 2011 |
MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis Y Yang, L Ding, Q Hu, J Xia, J Sun, X Wang, H Xiong, D Gurbani, L Li, ... Molecular cancer 16, 1-13, 2017 | 128 | 2017 |
Targeting aurora kinases limits tumour growth through DNA damage‐mediated senescence and blockade of NF‐κB impairs this drug‐induced senescence Y Liu, OE Hawkins, Y Su, AE Vilgelm, T Sobolik, YM Thu, S Kantrow, ... EMBO molecular medicine 5 (1), 149-166, 2013 | 102 | 2013 |
IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cells Y Liu, J Fuchs, C Li, J Lin Cell cycle 9 (17), 3423-3427, 2010 | 96 | 2010 |
Discovery of a selective inhibitor of doublecortin like kinase 1 FM Ferguson, B Nabet, S Raghavan, Y Liu, AL Leggett, M Kuljanin, ... Nature chemical biology 16 (6), 635-643, 2020 | 92 | 2020 |
Small compound inhibitors of basal glucose transport inhibit cell proliferation and induce apoptosis in cancer cells via glucose-deprivation-like mechanisms Y Liu, W Zhang, Y Cao, Y Liu, S Bergmeier, X Chen Cancer letters 298 (2), 176-185, 2010 | 92 | 2010 |
Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells AE Vilgelm, JS Pawlikowski, Y Liu, OE Hawkins, TA Davis, J Smith, ... Cancer research 75 (1), 181-193, 2015 | 87 | 2015 |
Regulation of G1 arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2α phosphorylation Y Liu, C László, Y Liu, W Liu, X Chen, SC Evans, S Wu Neoplasia 12 (1), 61-IN6, 2010 | 83 | 2010 |
Celecoxib inhibits interleukin-6/Interleukin-6 receptor–induced JAK2/STAT3 phosphorylation in human hepatocellular carcinoma cells Y Liu, A Liu, H Li, C Li, J Lin Cancer Prevention Research 4 (8), 1296-1305, 2011 | 80 | 2011 |
Tumor tissue microRNA expression in association with triple-negative breast cancer outcomes Y Liu, Q Cai, PP Bao, Y Su, H Cai, J Wu, F Ye, X Guo, W Zheng, Y Zheng, ... Breast cancer research and treatment 152, 183-191, 2015 | 73 | 2015 |
RAF265 inhibits the growth of advanced human melanoma tumors Y Su, AE Vilgelm, MC Kelley, OE Hawkins, Y Liu, KL Boyd, S Kantrow, ... Clinical cancer research 18 (8), 2184-2198, 2012 | 69 | 2012 |
MiR-374a suppresses lung adenocarcinoma cell proliferation and invasion by targeting TGFA gene expression H Wu, Y Liu, XO Shu, Q Cai Carcinogenesis 37 (6), 567-575, 2016 | 51 | 2016 |
STAT3 as a therapeutic target for glioblastoma Y Liu, C Li, J Lin Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2010 | 45 | 2010 |
LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells A Liu, Y Liu, PK Li, C Li, J Lin Anticancer research 31 (6), 2029-2035, 2011 | 39 | 2011 |
Regulation of hdm2 by stress-induced hdm2alt1 in tumor and nontumorigenic cell lines correlating with p53 stability CS Dias, Y Liu, A Yau, L Westrick, SC Evans Cancer research 66 (19), 9467-9473, 2006 | 38 | 2006 |
XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells Y Liu, A Liu, Z Xu, W Yu, H Wang, C Li, J Lin Apoptosis 16, 502-510, 2011 | 37 | 2011 |
XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells A Liu, Y Liu, Z Jin, Q Hu, L Lin, D Jou, J Yang, Z Xu, H Wang, C Li, J Lin Public Library of Science 7 (10), e46624, 2012 | 35 | 2012 |
ALDH1A1 mRNA expression in association with prognosis of triple-negative breast cancer Y Liu, M Baglia, Y Zheng, W Blot, PP Bao, H Cai, S Nechuta, W Zheng, ... Oncotarget 6 (38), 41360, 2015 | 34 | 2015 |
Novel small molecule, XZH‐5, inhibits constitutive and interleukin‐6‐induced STAT3 phosphorylation in human rhabdomyosarcoma cells A Liu, Y Liu, Z Xu, W Yu, H Wang, C Li, J Lin Cancer science 102 (7), 1381-1387, 2011 | 26 | 2011 |