| Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease CT Guy, RD Cardiff, WJ Muller Molecular and cellular biology 12 (3), 954-961, 1992 | 1895 | 1992 |
| Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. CT Guy, MA Webster, M Schaller, TJ Parsons, RD Cardiff, WJ Muller Proceedings of the National Academy of Sciences 89 (22), 10578-10582, 1992 | 1599 | 1992 |
| Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene WJ Muller, E Sinn, PK Pattengale, R Wallace, P Leder Cell 54 (1), 105-115, 1988 | 1530 | 1988 |
| Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases EY Lin, JG Jones, P Li, L Zhu, KD Whitney, WJ Muller, JW Pollard The American journal of pathology 163 (5), 2113-2126, 2003 | 1209 | 2003 |
| Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo E Sinn, W Muller, P Pattengale, I Tepler, R Wallace, P Leder Cell 49 (4), 465-475, 1987 | 1041 | 1987 |
| Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer KC Patra, Q Wang, PT Bhaskar, L Miller, Z Wang, W Wheaton, N Chandel, ... Cancer cell 24 (2), 213-228, 2013 | 812 | 2013 |
| ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation JY Yang, CS Zong, W Xia, H Yamaguchi, Q Ding, X Xie, JY Lang, CC Lai, ... Nature cell biology 10 (2), 138-148, 2008 | 793 | 2008 |
| Suppression of tumor growth and metastasis in Mgat5-deficient mice M Granovsky, J Fata, J Pawling, WJ Muller, R Khokha, JW Dennis Nature medicine 6 (3), 306-312, 2000 | 653 | 2000 |
| Oncogenes and tumor suppressor genes EYHP Lee, WJ Muller Cold Spring Harbor perspectives in biology 2 (10), a003236, 2010 | 631 | 2010 |
| Elevated expression of activated forms of Neu/ErbB‐2 and ErbB‐3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer PM Siegel, ED Ryan, RD Cardiff, WJ Muller The EMBO journal, 1999 | 611 | 1999 |
| β4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis W Guo, Y Pylayeva, A Pepe, T Yoshioka, WJ Muller, G Inghirami, ... Cell 126 (3), 489-502, 2006 | 581 | 2006 |
| Transforming growth factor β signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis PM Siegel, W Shu, RD Cardiff, WJ Muller, J Massagué Proceedings of the National Academy of Sciences 100 (14), 8430-8435, 2003 | 558 | 2003 |
| Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction DE White, NA Kurpios, D Zuo, JA Hassell, S Blaess, U Mueller, WJ Muller Cancer cell 6 (2), 159-170, 2004 | 503 | 2004 |
| Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation AM Cheng, TM Saxton, R Sakai, S Kulkarni, G Mbamalu, W Vogel, ... Cell 95 (6), 793-803, 1998 | 461 | 1998 |
| Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases S Liu, M Umezu-Goto, M Murph, Y Lu, W Liu, F Zhang, S Yu, LC Stephens, ... Cancer cell 15 (6), 539-550, 2009 | 432 | 2009 |
| Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway RJ Lee, C Albanese, M Fu, M D'Amico, B Lin, G Watanabe, GK Haines III, ... Molecular and cellular biology 20 (2), 672-683, 2000 | 428 | 2000 |
| The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer RL Dillon, DE White, WJ Muller Oncogene 26 (9), 1338-1345, 2007 | 413 | 2007 |
| Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis SG Julien, N Dubé, M Read, J Penney, M Paquet, Y Han, BP Kennedy, ... Nature genetics 39 (3), 338-346, 2007 | 382 | 2007 |
| Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo: role of Cav-1 in cell invasiveness and matrix metalloproteinase … TM Williams, F Medina, I Badano, RB Hazan, J Hutchinson, WJ Muller, ... Journal of Biological Chemistry 279 (49), 51630-51646, 2004 | 373 | 2004 |
| Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression J Hutchinson, J Jin, RD Cardiff, JR Woodgett, WJ Muller Molecular and cellular biology 21 (6), 2203-2212, 2001 | 361 | 2001 |
Vincent GiguereProfessor, McGill UniversityVerified email at mcgill.ca
