| The cell biology of the blood-brain barrier LL Rubin, JM Staddon Annual review of neuroscience 22 (1), 11-28, 1999 | 1319 | 1999 |
| A paracrine requirement for hedgehog signalling in cancer RL Yauch, SE Gould, SJ Scales, T Tang, H Tian, CP Ahn, D Marshall, ... Nature 455 (7211), 406-410, 2008 | 1183 | 2008 |
| Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors L Katsimpardi, NK Litterman, PA Schein, CM Miller, FS Loffredo, ... Science 344 (6184), 630-634, 2014 | 1071 | 2014 |
| A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death J Ham, C Babij, J Whitfield, CM Pfarr, D Lallemand, M Yaniv, LL Rubin Neuron 14 (5), 927-939, 1995 | 1022 | 1995 |
| Targeting the Hedgehog pathway in cancer LL Rubin, FJ de Sauvage Nature reviews Drug discovery 5 (12), 1026-1033, 2006 | 1019 | 2006 |
| A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ... Cell stem cell 5 (5), 491-503, 2009 | 955 | 2009 |
| A cell culture model of the blood-brain barrier. LL Rubin, DE Hall, S Porter, K Barbu, C Cannon, HC Horner, M Janatpour, ... The Journal of cell biology 115 (6), 1725-1735, 1991 | 918 | 1991 |
| Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches R Machold, S Hayashi, M Rutlin, MD Muzumdar, S Nery, JG Corbin, ... Neuron 39 (6), 937-950, 2003 | 873 | 2003 |
| Occludin as a possible determinant of tight junction permeability in endothelial cells T Hirase, JM Staddon, M Saitou, Y Ando-Akatsuka, M Itoh, M Furuse, ... Journal of cell science 110 (14), 1603-1613, 1997 | 816 | 1997 |
| Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation J Rihel, DA Prober, A Arvanites, K Lam, S Zimmerman, S Jang, ... Science 327 (5963), 348-351, 2010 | 773 | 2010 |
| A TALEN genome-editing system for generating human stem cell-based disease models Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ... Cell stem cell 12 (2), 238-251, 2013 | 703 | 2013 |
| Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/− p53−/− mice JT Romer, H Kimura, S Magdaleno, K Sasai, C Fuller, H Baines, ... Cancer cell 6 (3), 229-240, 2004 | 628 | 2004 |
| A small molecule that directs differentiation of human ESCs into the pancreatic lineage S Chen, M Borowiak, JL Fox, R Maehr, K Osafune, L Davidow, K Lam, ... Nature chemical biology 5 (4), 258-265, 2009 | 607 | 2009 |
| Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists M Frank-Kamenetsky, XM Zhang, S Bottega, O Guicherit, H Wichterle, ... Journal of biology 1, 1-19, 2002 | 591 | 2002 |
| In silico labeling: predicting fluorescent labels in unlabeled images EM Christiansen, SJ Yang, DM Ando, A Javaherian, G Skibinski, S Lipnick, ... Cell 173 (3), 792-803. e19, 2018 | 581 | 2018 |
| A comparison of non-integrating reprogramming methods TM Schlaeger, L Daheron, TR Brickler, S Entwisle, K Chan, A Cianci, ... Nature biotechnology 33 (1), 58-63, 2015 | 557 | 2015 |
| SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy NA Naryshkin, M Weetall, A Dakka, J Narasimhan, X Zhao, Z Feng, ... science 345 (6197), 688-693, 2014 | 546 | 2014 |
| Single-cell transcriptomic profiling of the aging mouse brain M Ximerakis, SL Lipnick, BT Innes, SK Simmons, X Adiconis, D Dionne, ... Nature neuroscience 22 (10), 1696-1708, 2019 | 485 | 2019 |
| GDC-0449—A potent inhibitor of the hedgehog pathway KD Robarge, SA Brunton, GM Castanedo, Y Cui, MS Dina, R Goldsmith, ... Bioorganic & medicinal chemistry letters 19 (19), 5576-5581, 2009 | 460 | 2009 |
| Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons A Watson, A Eilers, D Lallemand, J Kyriakis, LL Rubin, J Ham Journal of Neuroscience 18 (2), 751-762, 1998 | 452 | 1998 |
Anthony ArvanitesHarvard UniversityVerifierad e-postadress på post.harvard.edu
