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Jan Backmann
Jan Backmann
F.Hoffmann-La Roche Ltd
Verified email at roche.com
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Year
The crystal structure of triosephosphate isomerase (TIM) from Thermotoga maritima: a comparative thermostability structural analysis of ten different TIM structures
D Maes, JP Zeelen, N Thanki, N Beaucamp, M Alvarez, MHD Thi, ...
Proteins: Structure, Function, and Bioinformatics 37 (3), 441-453, 1999
1871999
Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic …
JC Williams, JP Zeelen, G Neubauer, G Vriend, J Backmann, ...
Protein engineering 12 (3), 243-250, 1999
1571999
Refolding of thermally and urea-denatured ribonuclease A monitored by time-resolved FTIR spectroscopy
D Reinstädler, H Fabian, J Backmann, D Naumann
Biochemistry 35 (49), 15822-15830, 1996
1451996
Impact of point mutations on the structure and thermal stability of ribonuclease T1 in aqueous solution probed by Fourier transform infrared spectroscopy
H Fabian, C Schultz, J Backmann, U Hahn, W Saenger, HH Mantsch, ...
Biochemistry 33 (35), 10725-10730, 1994
1281994
Hydrogen peroxide-induced structural alterations of RNAse A
P Lasch, T Petras, O Ullrich, J Backmann, D Naumann, T Grune
Journal of Biological Chemistry 276 (12), 9492-9502, 2001
1162001
Thermodynamics and kinetics of unfolding of the thermostable trimeric adenylate kinase from the archaeon Sulfolobus acidocaldarius
J Backmann, G Schäfer, L Wyns, H Bönisch
Journal of molecular biology 284 (3), 817-833, 1998
1081998
Intricate interactions within the ccd plasmid addiction system
MH Dao-Thi, D Charlier, R Loris, D Maes, J Messens, L Wyns, ...
Journal of Biological Chemistry 277 (5), 3733-3742, 2002
902002
The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase
AM Lambeir, J Backmann, J Ruiz‐Sanz, V Filimonov, JE Nielsen, ...
European Journal of Biochemistry 267 (9), 2516-2524, 2000
712000
Biophysical and structural properties of DNA· diC14-amidine complexes: Influence of the DNA/lipid ratio
V Pector, J Backmann, D Maes, M Vandenbranden, JM Ruysschaert
Journal of Biological Chemistry 275 (38), 29533-29538, 2000
672000
Adenylate Kinase fromSulfolobus acidocaldarius: Expression inEscherichia coliand Characterization by Fourier Transform Infrared Spectroscopy
H Bönisch, J Backmann, T Kath, D Naumann, G Schäfer
Archives of biochemistry and biophysics 333 (1), 75-84, 1996
471996
The thermodynamic stability of the proteins of the ccd plasmid addiction system
MH Dao-Thi, J Messens, L Wyns, J Backmann
Journal of Molecular Biology 299 (5), 1373-1386, 2000
462000
Analysis of a Water Mediated Protein−Protein Interactions within RNase T1,
U Langhorst, J Backmann, R Loris, J Steyaert
Biochemistry 39 (22), 6586-6593, 2000
452000
Thermally induced hydrogen exchange processes in small proteins as seen by FTIR spectroscopy
J Backmann, C Schultz, H Fabian, U Hahn, W Saenger, D Naumann
Proteins: Structure, Function, and Bioinformatics 24 (3), 379-387, 1996
441996
Temperature-jump-induced refolding of ribonuclease A: a time-resolved FTIR spectroscopic study
J Backmann, H Fabian, D Naumann
FEBS letters 364 (2), 175-178, 1995
421995
The structural differences between bovine lens αA‐and αB‐crystallin
S Abgar, J Backmann, T Aerts, J Vanhoudt, J Clauwaert
European Journal of Biochemistry 267 (19), 5916-5925, 2000
342000
Hydrophobic core manipulations in ribonuclease T1
S De Vos, J Backmann, M Prévost, J Steyaert, R Loris
Biochemistry 40 (34), 10140-10149, 2001
222001
Extended kinetic analysis of ribonuclease T1 variants leads to an improved scheme for the reaction mechanism
J Backmann, CC Doray, HP Grunert, O Landt, U Hahn
Biochemical and biophysical research communications 199 (1), 213-219, 1994
211994
Trp59 to Tyr substitution enhances the catalytic activity of RNase T1 and of the Tyr to Trp variants in positions 24, 42 and 45
HP Grunert, O Landt, M Zirpel-Giesebrecht, J Backmann, U Heinemann, ...
Protein Engineering, Design and Selection 6 (7), 739-744, 1993
201993
A correlation between thermal stability and structural features of staphylokinase and selected mutants: a Fourier-transform infrared study
U Dornberger, D Fandrei, J Backmann, W Hübner, K Rahmelow, ...
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1996
181996
X‐ray crystallographic and calorimetric studies of the effects of the mutation Trp59→ Tyr in ribonuclease T1
WD SCHUBERT, G Schluckebier, J Backmann, J Granzin, C Kisker, ...
European journal of biochemistry 220 (2), 527-534, 1994
181994
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