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Neeraj J Agrawal
Neeraj J Agrawal
Amgen
Verified email at seas.upenn.edu
Title
Cited by
Cited by
Year
Developability index: a rapid in silico tool for the screening of antibody aggregation propensity
TM Lauer, NJ Agrawal, N Chennamsetty, K Egodage, B Helk, BL Trout
Journal of pharmaceutical sciences 101 (1), 102-115, 2012
2082012
Gas solubility of H2S and CO2 in aqueous solutions of N-methyldiethanolamine
PJG Huttenhuis, NJ Agrawal, JA Hogendoorn, GF Versteeg
Journal of Petroleum Science and Engineering 55 (1-2), 122-134, 2007
1952007
Aggregation in protein-based biotherapeutics: computational studies and tools to identify aggregation-prone regions
NJ Agrawal, S Kumar, X Wang, B Helk, SK Singh, BL Trout
Journal of pharmaceutical sciences 100 (12), 5081-5095, 2011
1492011
Computational tool for the early screening of monoclonal antibodies for their viscosities
NJ Agrawal, B Helk, S Kumar, N Mody, HA Sathish, HS Samra, PM Buck, ...
MAbs 8 (1), 43-48, 2016
892016
Rational design of therapeutic mAbs against aggregation through protein engineering and incorporation of glycosylation motifs applied to bevacizumab
F Courtois, NJ Agrawal, TM Lauer, BL Trout
MAbs 8 (1), 99-112, 2016
882016
The solubility of carbon dioxide in aqueous N-methyldiethanolamine solutions
PJG Huttenhuis, NJ Agrawal, E Solbraa, GF Versteeg
Fluid phase equilibria 264 (1-2), 99-112, 2008
792008
Systems biology and physical biology of clathrin-mediated endocytosis
V Ramanan, NJ Agrawal, J Liu, S Engles, R Toy, R Radhakrishnan
Integrative biology 3 (8), 803-815, 2011
782011
Computational methods to predict therapeutic protein aggregation
PM Buck, S Kumar, X Wang, NJ Agrawal, BL Trout, SK Singh
Therapeutic proteins: Methods and protocols, 425-451, 2012
652012
Fast and scalable purification of a therapeutic full‐length antibody based on process crystallization
B Smejkal, NJ Agrawal, B Helk, H Schulz, M Giffard, M Mechelke, F Ortner, ...
Biotechnology and bioengineering 110 (9), 2452-2461, 2013
602013
Minimal mesoscale model for protein-mediated vesiculation in clathrin-dependent endocytosis
NJ Agrawal, J Nukpezah, R Radhakrishnan
PLoS computational biology 6 (9), e1000926, 2010
582010
Multivalent binding of nanocarrier to endothelial cells under shear flow
J Liu, NJ Agrawal, A Calderon, PS Ayyaswamy, DM Eckmann, ...
Biophysical journal 101 (2), 319-326, 2011
522011
The role of glycocalyx in nanocarrier-cell adhesion investigated using a thermodynamic model and Monte Carlo simulations
NJ Agrawal, R Radhakrishnan
The Journal of Physical Chemistry C 111 (43), 15848-15856, 2007
522007
Rational design of biobetters with enhanced stability
F Courtois, CP Schneider, NJ Agrawal, BL Trout
Journal of pharmaceutical sciences 104 (8), 2433-2440, 2015
492015
A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations
Y Liu, J Purvis, A Shih, J Weinstein, N Agrawal, R Radhakrishnan
Annals of biomedical engineering 35, 1012-1025, 2007
442007
Engineered IL-21 cytokine muteins fused to anti-PD-1 antibodies can improve CD8+ T cell function and anti-tumor immunity
S Shen, G Sckisel, DD Otter, J DeVoss, M Yang, K Ali
Frontiers in Immunology 11, 529464, 2020
412020
Solubility of carbon dioxide and hydrogen sulfide in aqueous N-methyldiethanolamine solutions
PJG Huttenhuis, NJ Agrawal, GF Versteeg
Industrial & engineering chemistry research 48 (8), 4051-4059, 2009
382009
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
ZW Junming Yie, Donghui SHI, David J. Lloyd, Jinghong Wang, Glenn N. SIVITS ...
US Patent App. US20170275370A1, 2017
32*2017
A computational tool to predict the evolutionarily conserved protein–protein interaction hot-spot residues from the structure of the unbound protein
NJ Agrawal, B Helk, BL Trout
FEBS letters 588 (2), 326-333, 2014
302014
Prediction of the hydrogen peroxide–induced methionine oxidation propensity in monoclonal antibodies
NJ Agrawal, A Dykstra, J Yang, H Yue, X Nguyen, C Kolvenbach, ...
Journal of Pharmaceutical Sciences 107 (5), 1282-1289, 2018
272018
Mesoscale simulations of curvature-inducing protein partitioning on lipid bilayer membranes in the presence of mean curvature fields
J Liu, R Tourdot, V Ramanan, NJ Agrawal, R Radhakrishanan
Molecular physics 110 (11-12), 1127-1137, 2012
252012
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