Modular Transcriptional Repertoire Analyses of Adults with Systemic Lupus Erythematosus Reveal Distinct Type I and Type II Interferon Signatures CD Chiche L, Jourde-Chiche N, Whalen E, Presnell S, Gersuk V, Dang K ... Arthritis Rheumatology, 2014 | 375 | 2014 |
A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders E Wambre, V Bajzik, JH DeLong, K O’Brien, QA Nguyen, C Speake, ... Science translational medicine 9 (401), eaam9171, 2017 | 345 | 2017 |
Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosis PS Linsley, C Speake, E Whalen, D Chaussabel PloS one 9 (10), e109760, 2014 | 196 | 2014 |
Vitamin D deficiency is associated with increased risk of non-alcoholic steatohepatitis in adults with non-alcoholic fatty liver disease: possible role for MAPK and NF-κB? JE Nelson, CL Roth, LA Wilson, KP Yates, B Aouizerat, ... Official journal of the American College of Gastroenterology| ACG 111 (6 …, 2016 | 131 | 2016 |
Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children MC Altman, MA Gill, E Whalen, DC Babineau, B Shao, AH Liu, B Jepson, ... Nature immunology 20 (5), 637-651, 2019 | 129 | 2019 |
CD4+ group 1 innate lymphoid cells (ILC) form a functionally distinct ILC subset that is increased in systemic sclerosis F Roan, TA Stoklasek, E Whalen, JA Molitor, JA Bluestone, JH Buckner, ... The Journal of Immunology 196 (5), 2051-2062, 2016 | 128 | 2016 |
Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4+CD25hi T Cells of Type 1 Diabetic and Multiple Sclerosis Patients K Cerosaletti, A Schneider, K Schwedhelm, I Frank, M Tatum, S Wei, ... PloS one 8 (12), e83811, 2013 | 119 | 2013 |
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression C Hundhausen, A Roth, E Whalen, J Chen, A Schneider, SA Long, S Wei, ... Science translational medicine 8 (356), 356ra119-356ra119, 2016 | 106 | 2016 |
Network structures and algorithms in Bioconductor VJ Carey, J Gentry, E Whalen, R Gentleman Bioinformatics 21 (1), 135-136, 2005 | 93 | 2005 |
Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria TM Tran, MB Jones, A Ongoiba, EM Bijker, R Schats, P Venepally, ... Scientific reports 6 (1), 31291, 2016 | 84 | 2016 |
Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes HM Akilesh, MB Buechler, JM Duggan, WO Hahn, B Matta, X Sun, ... Science 363 (6423), eaao5213, 2019 | 82 | 2019 |
graph: A package to handle graph data structures R Gentleman, E Whalen, W Huber, S Falcon R package, 2009 | 72 | 2009 |
Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis N Jourde-Chiche, E Whalen, B Gondouin, C Speake, V Gersuk, B Dussol, ... Rheumatology 56 (3), 477-487, 2017 | 69 | 2017 |
An interactive web application for the dissemination of human systems immunology data C Speake, S Presnell, K Domico, B Zeitner, A Bjork, D Anderson, ... Journal of translational medicine 13, 1-10, 2015 | 51 | 2015 |
Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function MC Altman, SR Reeves, AR Parker, E Whalen, KM Misura, KA Barrow, ... Journal of Allergy and Clinical Immunology 142 (2), 451-459, 2018 | 38 | 2018 |
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data MC Altman, D Rinchai, N Baldwin, M Toufiq, E Whalen, M Garand, ... Nature communications 12 (1), 4385, 2021 | 37 | 2021 |
Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma MC Altman, E Whalen, A Togias, GT O'Connor, LB Bacharier, ... Journal of Allergy and Clinical Immunology 142 (6), 1856-1866, 2018 | 35 | 2018 |
A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients’ plasma CD Khaenam P, Rinchai D, Altman MC, Chiche L, Buddhisa S, Kewcharoenwong C ... Journal of Translational Medicine, 2014 | 35 | 2014 |
Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a … MC Altman, M Kattan, G T O'Connor, RC Murphy, E Whalen, P LeBeau, ... The Lancet Planetary Health 7 (1), e33-e44, 2023 | 34 | 2023 |
An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity NE Weisser, M Sanches, E Escobar-Cabrera, J O’Toole, E Whalen, ... Nature Communications 14 (1), 1394, 2023 | 28 | 2023 |