| Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy 8 (4), 445–544., 2012 | 13448* | 2012 |
| Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product D Metodiewa, AK Jaiswal, N Cenas, E Dickancaité, J Segura-Aguilar Free radical biology and medicine 26 (1-2), 107-116, 1999 | 659 | 1999 |
| Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease FA Zucca, J Segura-Aguilar, E Ferrari, P Muñoz, I Paris, D Sulzer, T Sarna, ... Progress in neurobiology 155, 96-119, 2017 | 596 | 2017 |
| Protective and toxic roles of dopamine in Parkinson's disease J Segura‐Aguilar, I Paris, P Muñoz, E Ferrari, L Zecca, FA Zucca Journal of neurochemistry 129 (6), 898-915, 2014 | 507 | 2014 |
| Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative … S Baez, J Segura-Aguilar, M Widersten, AS Johansson, B Mannervik Biochemical Journal 324 (1), 25-28, 1997 | 431 | 1997 |
| The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems. RE Beyer, J Segura-Aguilar, S Di Bernardo, M Cavazzoni, R Fato, ... Proceedings of the National Academy of Sciences 93 (6), 2528-2532, 1996 | 379 | 1996 |
| Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy RL Vidal, A Figueroa, FA Court, P Thielen, C Molina, C Wirth, B Caballero, ... Human molecular genetics 21 (10), 2245-2262, 2012 | 263 | 2012 |
| Dopamine oxidation and autophagy P Muñoz, S Huenchuguala, I Paris, J Segura-Aguilar Parkinson’s disease 2012, 2012 | 238 | 2012 |
| On the mechanism of the Mn3+-induced neurotoxicity of dopamine: Prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase J Segura-Aguilar, C Lind Chemico-biological interactions 72 (3), 309-324, 1989 | 224 | 1989 |
| Cell lines as in vitro models for drug screening and toxicity studies DD Allen, R Caviedes, AM Cárdenas, T Shimahara, J Segura-Aguilar, ... Drug development and industrial pharmacy 31 (8), 757-768, 2005 | 200 | 2005 |
| Human class Mu glutathione transferases, in particular isoenzyme M2-2, catalyze detoxication of the dopamine metabolite aminochrome J Segura-Aguilar, S Baez, M Widersten, CJ Welch, B Mannervik Journal of Biological Chemistry 272 (9), 5727-5731, 1997 | 155 | 1997 |
| Copper neurotoxicity is dependent on dopamine‐mediated copper uptake and one‐electron reduction of aminochrome in a rat substantia nigra neuronal cell line I Paris, A Dagnino‐Subiabre, K Marcelain, LB Bennett, P Caviedes, ... Journal of neurochemistry 77 (2), 519-529, 2001 | 153 | 2001 |
| Regioselectivity and reversibility of the glutathione conjugation of quercetin quinone methide MG Boersma, J Vervoort, H Szymusiak, K Lemanska, B Tyrakowska, ... Chemical Research in Toxicology 13 (3), 185-191, 2000 | 152 | 2000 |
| Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects J Segura-Aguilar, D Metodiewa, CJ Welch Biochimica et Biophysica Acta (BBA)-General Subjects 1381 (1), 1-6, 1998 | 142 | 1998 |
| Are dopamine oxidation metabolites involved in the loss of dopaminergic neurons in the nigrostriatal system in Parkinson’s disease? A Herrera, P Muñoz, HWM Steinbusch, J Segura-Aguilar ACS Chemical Neuroscience 8 (4), 702-711, 2017 | 136 | 2017 |
| Glutathione transferase M2-2 catalyzes conjugation of dopamine and dopa o-quinones A Dagnino-Subiabre, BK Cassels, S Baez, AS Johansson, B Mannervik, ... Biochemical and biophysical research communications 274 (1), 32-36, 2000 | 132 | 2000 |
| DT-Diaphorase maintains the reduced state of ubiquinones in lipid vesicles thereby promoting their antioxidant function L Landi, D Fiorentini, MC Galli, J Segura-Aguilar, RE Beyer Free Radical Biology and Medicine 22 (1-2), 329-335, 1997 | 131 | 1997 |
| On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation C Arriagada, I Paris, MJS de las Matas, P Martinez-Alvarado, S Cardenas, ... Neurobiology of Disease 16 (2), 468-477, 2004 | 121 | 2004 |
| Neurotoxins and neurotoxic species implicated in neurodegeneration J Segura-Aguilar, RM Kostrzewa Neurotoxicity research 6, 615-630, 2004 | 117 | 2004 |
| Effect of superoxide dismutase on the autoxidation of various hydroquinones—a possible role of superoxide dismutase as a superoxide: semiquinone oxidoreductase E Cadenas, D Mira, A Brunmark, C Lind, J Segura-Aguilar, L Ernster Free Radical Biology and Medicine 5 (2), 71-79, 1988 | 116 | 1988 |
Patricia Muñoz GarcíaMD, PhD. Hospital Gregorio Marañón. IISGM. Universidad Complutense. CIBERES.Verified email at hggm.es
