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Gizem Karsli Uzunbas
Gizem Karsli Uzunbas
Research Scientist at Broad Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ...
Genes & development 25 (5), 460-470, 2011
14362011
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
JY Guo, G Karsli-Uzunbas, R Mathew, SC Aisner, JJ Kamphorst, ...
Genes & development 27 (13), 1447-1461, 2013
6022013
Autophagy is required for glucose homeostasis and lung tumor maintenance
G Karsli-Uzunbas, JY Guo, S Price, X Teng, SV Laddha, S Khor, ...
Cancer discovery 4 (8), 914-927, 2014
5242014
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
AM Strohecker, JY Guo, G Karsli-Uzunbas, SM Price, GJ Chen, R Mathew, ...
Cancer discovery 3 (11), 1272-1285, 2013
4582013
Autophagy promotes mammalian survival by suppressing oxidative stress and p53
Y Yang, G Karsli-Uzunbas, L Poillet-Perez, A Sawant, ZS Hu, Y Zhao, ...
Genes & development 34 (9-10), 688-700, 2020
772020
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
Journal of Cell Biology 212 (5), 545-560, 2016
642016
Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discov. 2014; 4: 914–27. doi: 10.1158/2159-8290
G Karsli-Uzunbas, JY Guo, S Price, X Teng, SV Laddha, S Khor, ...
CD-14-0363, 0
39
Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling
C Bodur, O Kutuk, G Karsli-Uzunbas, TT Isimjan, P Harrison, H Basaga
PLoS One 8 (2), e56369, 2013
322013
Control of p53-dependent transcription and enhancer activity by the p53 family member p63
GK Uzunbas, F Ahmed, MA Sammons
Journal of Biological Chemistry 294 (27), 10720-10736, 2019
292019
Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
AN Catizone, GK Uzunbas, P Celadova, S Kuang, D Bose, MA Sammons
Nucleic Acids Research 48 (8), 4195-4213, 2020
152020
Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions
F Siegel, S Siegel, K Graham, B Kaplan, K Petersen, U Boemer, ...
Cancer Research 81 (13_Supplement), 1470-1470, 2021
62021
BAY 2927088: The first non-covalent, potent, and selective tyrosine kinase inhibitor targeting EGFR exon 20 insertions and C797S resistance mutations in NSCLC
F Siegel, S Siegel, K Graham, G Karsli-Uzunbas, D Korr, J Schroeder, ...
European Journal of Cancer 174, S9-S10, 2022
42022
Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer
F Siegel, G Karsli-Uzunbas, K Kotynkova, Q McVeigh, S Siegel, D Korr, ...
Cancer Research 83 (7_Supplement), 4035-4035, 2023
22023
Cell type-dependent control of p53 transcription and enhancer activity by p63
GK Uzunbas, F Ahmed, MA Sammons
bioRxiv, 268649, 2018
22018
Stromal autophagy is required for the growth of cutaneous melanoma
RE Zhang, NJ Guo, N Krishnan, D Jelinek, GK Uzunbas, X Xie, A Gertych, ...
Cancer Research 76 (14_Supplement), 4081-4081, 2016
2016
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide (vol 212, pg 545, 2016)
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
JOURNAL OF CELL BIOLOGY 212 (7), 879-879, 2016
2016
Autophagy in tissue homeostasis and cancer
G Karsli Uzunbas
Rutgers University-Graduate School-New Brunswick, 2015
2015
Research Communications
W Hu, B Yuan, J Flygare, HF Lodish, T Shimi, V Butin-Israeli, SA Adam, ...
GENES & DEVELOPMENT, 2011
2011
JCB: Correction
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
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Articles 1–19