| Identification of poly-N-acetylglucosamine as a major polysaccharide component of the Bacillus subtilis biofilm matrix D Roux, C Cywes-Bentley, YF Zhang, S Pons, M Konkol, DB Kearns, ... Journal of Biological Chemistry 290 (31), 19261-19272, 2015 | 119 | 2015 |
| Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus*♦ NC Bamford, BD Snarr, FN Gravelat, DJ Little, MJ Lee, CA Zacharias, ... Journal of Biological Chemistry 290 (46), 27438-27450, 2015 | 94 | 2015 |
| The structure-and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1, 6-N-acetyl-D-glucosamine DJ Little, J Poloczek, JC Whitney, H Robinson, M Nitz, PL Howell Journal of Biological Chemistry 287 (37), 31126-31137, 2012 | 89 | 2012 |
| Characterization of the Pseudomonas aeruginosa glycoside hydrolase PslG reveals that its levels are critical for Psl polysaccharide biosynthesis and biofilm formation P Baker, GB Whitfield, PJ Hill, DJ Little, MJ Pestrak, H Robinson, ... Journal of Biological Chemistry 290 (47), 28374-28387, 2015 | 87 | 2015 |
| P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation P Baker, T Ricer, PJ Moynihan, EN Kitova, MTC Walvoort, DJ Little, ... PLoS pathogens 10 (8), e1004334, 2014 | 71 | 2014 |
| Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6-N-acetyl-d-glucosamine DJ Little, G Li, C Ing, BR DiFrancesco, NC Bamford, H Robinson, M Nitz, ... Proceedings of the National Academy of Sciences 111 (30), 11013-11018, 2014 | 69 | 2014 |
| PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β (1, 6)-N-acetylglucosamine and can disrupt bacterial biofilms DJ Little, R Pfoh, F Le Mauff, NC Bamford, C Notte, P Baker, M Guragain, ... PLoS pathogens 14 (4), e1006998, 2018 | 66 | 2018 |
| Functional Characterization of Staphylococcus epidermidis IcaB, a De-N-acetylase Important for Biofilm Formation V Pokrovskaya, J Poloczek, DJ Little, H Griffiths, PL Howell, M Nitz Biochemistry 52 (32), 5463-5471, 2013 | 53 | 2013 |
| PilN binding modulates the structure and binding partners of the Pseudomonas aeruginosa type IVa pilus protein PilM M McCallum, S Tammam, DJ Little, H Robinson, J Koo, M Shah, ... Journal of biological Chemistry 291 (21), 11003-11015, 2016 | 52 | 2016 |
| PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides D Sychantha, DJ Little, RN Chapman, GJ Boons, H Robinson, PL Howell, ... Nature chemical biology 14 (1), 79-85, 2018 | 46 | 2018 |
| The protein BpsB is a poly-β-1, 6-N-acetyl-D-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica DJ Little, S Milek, NC Bamford, T Ganguly, BR DiFrancesco, M Nitz, ... Journal of Biological Chemistry 290 (37), 22827-22840, 2015 | 46 | 2015 |
| In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA) D Sychantha, CS Jones, DJ Little, PJ Moynihan, H Robinson, NF Galley, ... PLoS pathogens 13 (10), e1006667, 2017 | 41 | 2017 |
| Structural basis for the de-N-acetylation of poly-β-1, 6-N-acetyl-D-glucosamine in Gram-positive bacteria DJ Little, NC Bamford, V Pokrovskaya, H Robinson, M Nitz, PL Howell Journal of Biological Chemistry 289 (52), 35907-35917, 2014 | 35 | 2014 |
| Synthesis and evaluation of inhibitors of E. coli PgaB, a polysaccharide de-N-acetylase involved in biofilm formation A Chibba, J Poloczek, DJ Little, PL Howell, M Nitz Organic & biomolecular chemistry 10 (35), 7103-7107, 2012 | 34 | 2012 |
| Regulatory evolution drives evasion of host inflammasomes by Salmonella Typhimurium B Ilyas, DT Mulder, DJ Little, W Elhenawy, MM Banda, D Pérez-Morales, ... Cell Reports 25 (4), 825-832. e5, 2018 | 30 | 2018 |
| Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli D Valleau, DJ Little, D Borek, T Skarina, AT Quaile, R Di Leo, S Houliston, ... Proceedings of the National Academy of Sciences 115 (40), 10004-10009, 2018 | 25 | 2018 |
| Combining in situ proteolysis and mass spectrometry to crystallize Escherichia coli PgaB DJ Little, JC Whitney, H Robinson, P Yip, M Nitz, PL Howell Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 25 | 2012 |
| Direct Staudinger–Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De‐N‐acetylases R Ariyakumaran, V Pokrovskaya, DJ Little, PL Howell, M Nitz ChemBioChem 16 (9), 1350-1356, 2015 | 15 | 2015 |
| Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli DJ Little, BK Coombes PLoS Pathogens 14 (8), e1007224, 2018 | 14 | 2018 |
| The TPR domain of PgaA is a multifunctional scaffold that binds PNAG and modulates PgaB-dependent polymer processing R Pfoh, AS Subramanian, J Huang, DJ Little, A Forman, BR DiFrancesco, ... PLoS Pathogens 18 (8), e1010750, 2022 | 4 | 2022 |
Natalie C BamfordEMBO SolutionsVerifierad e-postadress på embosolutions.org
