Single-molecule FRET imaging of GPCR dimers in living cells WB Asher, P Geggier, MD Holsey, GT Gilmore, AK Pati, J Meszaros, ... Nature methods 18 (4), 397-405, 2021 | 129 | 2021 |
Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging Q Zheng, S Jockusch, Z Zhou, RB Altman, H Zhao, W Asher, M Holsey, ... Chemical science 8 (1), 755-762, 2017 | 60 | 2017 |
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision WB Asher, DS Terry, GGA Gregorio, AW Kahsai, A Borgia, B Xie, A Modak, ... Cell 185 (10), 1661-1675. e16, 2022 | 49 | 2022 |
A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects S Chakraborty, JF DiBerto, A Faouzi, SM Bernhard, AM Gutridge, ... Journal of medicinal chemistry 64 (18), 13873-13892, 2021 | 40 | 2021 |
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores AK Pati, O El Bakouri, S Jockusch, Z Zhou, RB Altman, GA Fitzgerald, ... Proceedings of the National Academy of Sciences 117 (39), 24305-24315, 2020 | 34 | 2020 |
A heme fusion tag for protein affinity purification and quantification WB Asher, KL Bren Protein Science 19 (10), 1830-1839, 2010 | 28 | 2010 |
A novel luminescence-based β-arrestin recruitment assay for unmodified receptors MH Pedersen, J Pham, H Mancebo, A Inoue, WB Asher, JA Javitch Journal of Biological Chemistry 296, 2021 | 20 | 2021 |
Cytochrome c heme lyase can mature a fusion peptide composed of the amino-terminal residues of horse cytochrome c WB Asher, KL Bren Chemical communications 48 (67), 8344-8346, 2012 | 15 | 2012 |
A Two Model Receptor System of the Alpha1D Adrenergic Receptor To Describe Interactions with Epinephrine and BMY7378 DL Bautista, DH Morris, L Stein, W Asher, T Hammitt Journal of chemical information and modeling 46 (1), 334-344, 2006 | 9 | 2006 |
Differential activity of mGlu7 allosteric modulators provides evidence for mGlu7/8 heterodimers at hippocampal Schaffer collateral-CA1 synapses X Lin, NM Fisher, S Dogra, RK Senter, CW Reed, JJ Kalbfleisch, ... Journal of Biological Chemistry 298 (10), 2022 | 8 | 2022 |
Extreme vetting of dopamine receptor oligomerization WB Asher, S Mathiasen, MD Holsey, SG Grinnell, NA Lambert, JA Javitch G-Protein-Coupled Receptor Dimers, 99-127, 2017 | 8 | 2017 |
Two Model System of the α1A-Adrenoceptor Docked with Selected Ligands WB Asher, SN Hoskins, LA Slasor, DH Morris, EM Cook, DL Bautista Journal of chemical information and modeling 47 (5), 1906-1912, 2007 | 8 | 2007 |
Efficient and flexible preparation of biosynthetic microperoxidases EC Kleingardner, WB Asher, KL Bren Biochemistry 56 (1), 143-148, 2017 | 7 | 2017 |
Single-Molecule Analysis of Cytochrome c Folding by Monitoring the Lifetime of an Attached Fluorescent Probe AJ Lee, WB Asher, HA Stern, KL Bren, TD Krauss The journal of physical chemistry letters 4 (16), 2727-2733, 2013 | 7 | 2013 |
Affinity purification of heme-tagged proteins WB Asher, KL Bren Protein Affinity Tags: Methods and Protocols, 17-33, 2014 | 4 | 2014 |
Assays for detecting arrestin interaction with GPCRs NA Perry-Hauser, WB Asher, MH Pedersen, JA Javitch Methods in cell biology 166, 43-65, 2021 | 3 | 2021 |
Development of the Human Mu, Kappa, and Delta Opioid Receptors and Docking with Morphine DL Bautista, W Asher, L Carpenter Journal of the Kentucky Academy of Science 66 (2), 107-117, 2005 | 3 | 2005 |
Method and system for purifying and quantitating proteins using heme fusion tags KL Bren, WB Asher US Patent 8,815,533, 2014 | 2 | 2014 |
Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2 JE Petersen, MH Pedersen, O Dmytriyeva, E Nellemose, T Arora, ... Molecular Metabolism 74, 101757, 2023 | 1 | 2023 |
Promiscuous G-protein activation by the calcium-sensing receptor H Zuo, J Park, A Frangaj, J Ye, G Lu, JJ Manning, WB Asher, Z Lu, G Hu, ... Nature, 1-8, 2024 | | 2024 |