Jennifer J. Trowbridge
Jennifer J. Trowbridge
Assistant Professor, The Jackson Laboratory
Verifierad e-postadress på jax.org
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DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
JJ Trowbridge, JW Snow, J Kim, SH Orkin
Cell stem cell 5 (4), 442-449, 2009
3442009
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
JJ Trowbridge, A Xenocostas, RT Moon, M Bhatia
Nature medicine 12 (1), 89-98, 2006
2762006
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration
JJ Trowbridge, MP Scott, M Bhatia
Proceedings of the National Academy of Sciences 103 (38), 14134-14139, 2006
2102006
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
J Xu, DE Bauer, MA Kerenyi, TD Vo, S Hou, YJ Hsu, H Yao, JJ Trowbridge, ...
Proceedings of the National Academy of Sciences 110 (16), 6518-6523, 2013
1872013
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
A Burberry, N Suzuki, JY Wang, R Moccia, DA Mordes, MH Stewart, ...
Science translational medicine 8 (347), 347ra93-347ra93, 2016
1602016
Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains
JJ Trowbridge, AU Sinha, N Zhu, M Li, SA Armstrong, SH Orkin
Genes & development 26 (4), 344-349, 2012
1272012
Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior
F Shojaei, J Trowbridge, L Gallacher, L Yuefei, D Goodale, F Karanu, ...
Developmental cell 8 (5), 651-663, 2005
772005
Context-dependent function of “GATA switch” sites in vivo
JW Snow, JJ Trowbridge, KD Johnson, T Fujiwara, NE Emambokus, ...
Blood 117 (18), 4769-4772, 2011
562011
A single cis element maintains repression of the key developmental regulator Gata2
JW Snow, JJ Trowbridge, T Fujiwara, NE Emambokus, JA Grass, ...
PLoS Genet 6 (9), e1001103, 2010
552010
The lethal sex gap: COVID-19
EJ Márquez, J Trowbridge, GA Kuchel, J Banchereau, D Ucar
Immunity & Ageing 17 (1), 1-8, 2020
462020
A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis
M Rosu-Myles, E Stewart, J Trowbridge, CY Ito, P Zandstra, M Bhatia
Journal of cell science 118 (19), 4343-4352, 2005
452005
Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging
K Young, S Borikar, R Bell, L Kuffler, V Philip, JJ Trowbridge
Journal of Experimental Medicine 213 (11), 2259-2267, 2016
432016
Hematopoietic stem cell biology: too much of a Wnt thing
JJ Trowbridge, RT Moon, M Bhatia
Nature immunology 7 (10), 1021-1023, 2006
432006
Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells
J George, A Uyar, K Young, L Kuffler, K Waldron-Francis, E Marquez, ...
Nature communications 7 (1), 1-12, 2016
382016
Dnmt3a silences hematopoietic stem cell self-renewal
JJ Trowbridge, SH Orkin
Nature genetics 44 (1), 13-14, 2012
372012
Methods for regulation of stem cells
RT Moon, M Bhatia, JJ Trowbridge
US Patent 7,850,960, 2010
372010
DNA methylation in adult stem cells: New insights into self-renewal
JJ Trowbridge, SH Orkin
Epigenetics 5 (3), 189-193, 2010
362010
Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis
MA Loberg, RK Bell, LO Goodwin, E Eudy, LA Miles, JM SanMiguel, ...
Leukemia 33 (7), 1635-1649, 2019
332019
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes
X Bai, JJ Trowbridge, E Riley, JA Lee, A DiBiase, VM Kaartinen, SH Orkin, ...
Developmental biology 373 (2), 422-430, 2013
312013
Wnt3a Activates Dormant c‐Kit Bone Marrow‐Derived Cells with Short‐Term Multilineage Hematopoietic Reconstitution Capacity
JJ Trowbridge, B Guezguez, RT Moon, M Bhatia
Stem Cells 28 (8), 1379-1389, 2010
302010
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Artiklar 1–20