John James
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Biophysical mechanism of T-cell receptor triggering in a reconstituted system
JR James, RD Vale
Nature 487 (7405), 64-69, 2012
A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer
JR James, MI Oliveira, AM Carmo, A Iaboni, SJ Davis
Nature methods 3 (12), 1001-1006, 2006
Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing
J Li, NJ Stagg, J Johnston, MJ Harris, SA Menzies, D DiCara, V Clark, ...
Cancer cell 31 (3), 383-395, 2017
Crystal structure of a soluble CD28-Fab complex
EJ Evans, RM Esnouf, R Manso-Sancho, RJC Gilbert, JR James, C Yu, ...
Nature immunology 6 (3), 271-279, 2005
Selective, rapid and optically switchable regulation of protein function in live mammalian cells
YH Tsai, S Essig, JR James, K Lang, JW Chin
Nature chemistry 7 (7), 554-561, 2015
MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
X Li, S Thome, X Ma, M Amrute-Nayak, A Finigan, L Kitt, L Masters, ...
Nature communications 8 (1), 15986, 2017
Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells
JR James, SS White, RW Clarke, AM Johansen, PD Dunne, DL Sleep, ...
Proceedings of the National Academy of Sciences 104 (45), 17662-17667, 2007
The platelet receptor CLEC-2 is active as a dimer
AA Watson, CM Christou, JR James, AE Fenton-May, GE Moncayo, ...
Biochemistry 48 (46), 10988-10996, 2009
Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance
Z Zhang, F Gothe, P Pennamen, JR James, D McDonald, CP Mata, ...
Journal of Experimental Medicine 216 (6), 1311-1327, 2019
DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking
PD Dunne, RA Fernandes, J McColl, JW Yoon, JR James, SJ Davis, ...
Biophysical Journal 97 (4), L5-L7, 2009
Experimental challenge to a'rigorous' BRET analysis of GPCR oligomerization
A Salahpour, B Masri
Nature Methods 4 (8), 599-600, 2007
Tuning ITAM multiplicity on T cell receptors can control potency and selectivity to ligand density
JR James
Science signaling 11 (531), eaan1088, 2018
Glycoprotein VI oligomerization in cell lines and platelets
O Berlanga, T BORI‐SANZ, JR James, J Frampton, SJ Davis, ...
Journal of Thrombosis and Haemostasis 5 (5), 1026-1033, 2007
The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, ...
Journal of Biological Chemistry 286 (37), 31993-32001, 2011
Distinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function
S Banerji, BRS Hide, JR James, MEM Noble, DG Jackson
Journal of biological chemistry 285 (14), 10724-10735, 2010
Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells
A Liaunardy-Jopeace, BL Murton, M Mahesh, JW Chin, JR James
Nature structural & molecular biology 24 (12), 1155-1163, 2017
A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase
M Bamberger, AM Santos, CM Gonçalves, MI Oliveira, JR James, ...
Journal of Biological Chemistry 286 (35), 30324-30336, 2011
Ferroportin: lack of evidence for multimers
LM Schimanski, H Drakesmith, C Talbott, K Horne, JR James, SJ Davis, ...
Blood Cells, Molecules, and Diseases 40 (3), 360-369, 2008
Quantifying persistence in the T‐cell signaling network using an optically controllable antigen receptor
MJ Harris, M Fuyal, JR James
Molecular Systems Biology 17 (5), e10091, 2021
Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions
M Kästle, C Merten, R Hartig, T Kaehne, A Liaunardy-Jopeace, ...
Cell Communication and Signaling 18, 1-18, 2020
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