Targeted delivery of antisense oligonucleotides to pancreatic β-cells C Ämmälä, WJ Drury III, L Knerr, I Ahlstedt, P Stillemark-Billton, ... Science advances 4 (10), eaat3386, 2018 | 169 | 2018 |
Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it M Karlsson, DLI Janzén, L Durrieu, A Colman-Lerner, MC Kjellsson, ... BMC systems biology 9, 1-15, 2015 | 57 | 2015 |
Parameter identifiability of fundamental pharmacodynamic models DLI Janzén, L Bergenholm, M Jirstrand, J Parkinson, J Yates, ND Evans, ... Frontiers in Physiology 7, 590, 2016 | 56 | 2016 |
Glucagon like peptide 1 receptor agonists for targeted delivery of antisense oligonucleotides to pancreatic beta cell L Knerr, TP Prakash, R Lee, WJ Drury III, M Nikan, W Fu, E Pirie, LD Maria, ... Journal of the American Chemical Society 143 (9), 3416-3429, 2021 | 54 | 2021 |
Translational model to predict pulmonary pharmacokinetics and efficacy in man for inhaled bronchodilators R Hendrickx, E Lamm Bergström, DLI Janzén, M Fridén, U Eriksson, ... CPT: pharmacometrics & systems pharmacology 7 (3), 147-157, 2018 | 39 | 2018 |
Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates L Weidolf, A Björkbom, A Dahlén, M Elebring, P Gennemark, M Hölttä, ... Drug discovery today 26 (10), 2244-2258, 2021 | 28 | 2021 |
In vitro and in vivo evaluation of 3D printed capsules with pressure triggered release mechanism for oral peptide delivery S Berg, J Krause, A Björkbom, K Walter, S Harun, A Granfeldt, D Janzén, ... Journal of Pharmaceutical Sciences 110 (1), 228-238, 2021 | 28 | 2021 |
Physiologically based pharmacokinetic model of itraconazole and two of its metabolites to improve the predictions and the mechanistic understanding of CYP3A4 drug-drug interactions LP Garcia, D Janzén, KP Kanebratt, H Ericsson, H Lennernäs, A Lundahl Drug Metabolism and Disposition 46 (10), 1420-1433, 2018 | 28 | 2018 |
Three novel approaches to structural identifiability analysis in mixed-effects models DLI Janzén, M Jirstrand, MJ Chappell, ND Evans Computer Methods and Programs in Biomedicine 171, 141-152, 2019 | 26 | 2019 |
Model‐based assessment of variability in isoniazid pharmacokinetics and metabolism in patients co‐infected with tuberculosis and HIV: implications for a novel dosing strategy J Sundell, E Bienvenu, D Janzén, S Birgersson, A Äbelö, M Ashton Clinical Pharmacology & Therapeutics 108 (1), 73-80, 2020 | 21 | 2020 |
Antisense therapy attenuates phospholamban p.(Arg14del) cardiomyopathy in mice and reverses protein aggregation TR Eijgenraam, NM Stege, V Oliveira Nunes Teixeira, R de Brouwer, ... International Journal of Molecular Sciences 23 (5), 2427, 2022 | 15 | 2022 |
Extending existing structural identifiability analysis methods to mixed-effects models DLI Janzén, M Jirstrand, MJ Chappell, ND Evans Mathematical Biosciences 295, 1-10, 2018 | 9 | 2018 |
Evaluation in pig of an intestinal administration device for oral peptide delivery S Berg, T Uggla, M Antonsson, SF Nunes, M Englund, L Rosengren, ... Journal of Controlled Release 353, 792-801, 2023 | 8 | 2023 |
Characterization of cell-to-cell variation in nuclear transport rates and identification of its sources L Durrieu, A Bush, A Grande, R Johansson, D Janzén, A Katz, ... Iscience 26 (1), 2023 | 7 | 2023 |
Diffusive molecular communication with a spheroidal receiver for organ-on-chip systems H Arjmandi, M Zoofaghari, M Rezaei, K Kanebratt, L Vilen, D Janzen, ... ICC 2023-IEEE International Conference on Communications, 4464-4469, 2023 | 6 | 2023 |
Structural Identifiability in Mixed-Effects Models: Two different approaches D Janzén 9th IFAC Symposium on Biological and Medical Systems, 2015 | 4 | 2015 |
Standard two-stage and Nonlinear mixed effect modelling for determination of cell-to-cell variation of transport parameters in Saccharomyces cerevisiae D Janzén | 4 | 2012 |
Spheroidal Molecular Communication via Diffusion: Signaling Between Homogeneous Cell Aggregates M Rezaei, H Arjmandi, M Zoofaghari, K Kanebratt, L Vilén, D Janzén, ... IEEE Transactions on Molecular, Biological and Multi-Scale Communications 10 …, 2024 | 3 | 2024 |
Input estimation for extended-release formulations exemplified with exenatide M Trägĺrdh, MJ Chappell, JE Palm, ND Evans, DLI Janzén, P Gennemark Frontiers in Bioengineering and Biotechnology 5, 24, 2017 | 3 | 2017 |
Structural identifiability and indistinguishability in mixed-effects models D Janzén University of Warwick, 2016 | 2 | 2016 |