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David Tomasek
David Tomasek
Novartis Institutes for BioMedical Research
Verifierad e-postadress på novartis.com
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Structure of a nascent membrane protein as it folds on the BAM complex
D Tomasek, S Rawson, J Lee, JS Wzorek, SC Harrison, Z Li, D Kahne
Nature 583 (7816), 473-478, 2020
1152020
Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation
VI Petrou, CM Herrera, KM Schultz, OB Clarke, J Vendome, D Tomasek, ...
Science 351 (6273), 608-612, 2016
1092016
Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors
G Zhang, V Baidin, KS Pahil, E Moison, D Tomasek, NS Ramadoss, ...
Proceedings of the National Academy of Sciences 115 (26), 6834-6839, 2018
842018
Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA
J Lee, D Tomasek, TMA Santos, MD May, I Meuskens, D Kahne
Elife 8, e49787, 2019
642019
Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion
J Lee, HA Sutterlin, JS Wzorek, MD Mandler, CL Hagan, M Grabowicz, ...
Proceedings of the National Academy of Sciences 115 (10), 2359-2364, 2018
612018
The assembly of β-barrel outer membrane proteins
D Tomasek, D Kahne
Current Opinion in Microbiology 60, 16-23, 2021
512021
Structural basis for phosphatidylinositol-phosphate biosynthesis
OB Clarke, D Tomasek, CD Jorge, MB Dufrisne, M Kim, S Banerjee, ...
Nature Communications 6 (1), 8505, 2015
502015
Structural basis for catalysis in a CDP-alcohol phosphotransferase
G Sciara, OB Clarke, D Tomasek, B Kloss, S Tabuso, R Byfield, R Cohn, ...
Nature communications 5 (1), 4068, 2014
502014
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis
C Ardiccioni, OB Clarke, D Tomasek, HA Issa, DC Von Alpen, HL Pond, ...
Nature communications 7 (1), 10175, 2016
382016
Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop
JS Wzorek, J Lee, D Tomasek, CL Hagan, DE Kahne
Proceedings of the National Academy of Sciences 114 (10), 2598-2603, 2017
372017
Mechanism of outer membrane protein assembly by the Bam complex
D Tomasek
Harvard University, 2020
2020
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Artiklar 1–11