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Raminta Venskutonyte
Raminta Venskutonyte
Researcher, Lund University
Verifierad e-postadress på med.lu.se
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Structural basis for glycerol efflux and selectivity of human aquaporin 7
SW de Mare, R Venskutonytė, S Eltschkner, BL de Groot, ...
Structure 28 (2), 215-222. e3, 2020
572020
Invisible detergents for structure determination of membrane proteins by small‐angle neutron scattering
SR Midtgaard, TA Darwish, MC Pedersen, P Huda, AH Larsen, ...
The FEBS journal 285 (2), 357-371, 2018
572018
Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate …
Z Assaf, AP Larsen, R Venskutonytė, L Han, B Abrahamsen, B Nielsen, ...
Journal of medicinal chemistry 56 (4), 1614-1628, 2013
512013
Protein engineering allows for mild affinity-based elution of therapeutic antibodies
S Kanje, R Venskutonytė, J Scheffel, J Nilvebrant, K Lindkvist-Petersson, ...
Journal of molecular biology 430 (18), 3427-3438, 2018
362018
Nanoscale mobility of the apo state and TARP stoichiometry dictate the gating behavior of alternatively spliced AMPA receptors
GB Dawe, MF Kadir, R Venskutonytė, AM Perozzo, Y Yan, ...
Neuron 102 (5), 976-992. e5, 2019
322019
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate
R Venskutonytė, K Frydenvang, M Gajhede, L Bunch, DS Pickering, ...
Journal of structural biology 176 (3), 307-314, 2011
262011
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance
H Åbacka, JS Hansen, P Huang, R Venskutonytė, A Hyrenius-Wittsten, ...
Haematologica 106 (4), 1163, 2021
242021
Selective Kainate Receptor (GluK1) Ligands Structurally Based upon 1H-Cyclopentapyrimidin-2,4(1H,3H)-dione: Synthesis, Molecular Modeling, and …
R Venskutonyte, S Butini, S Sanna Coccone, S Gemma, M Brindisi, ...
Journal of medicinal chemistry 54 (13), 4793-4805, 2011
242011
Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors
S Møllerud, A Pinto, L Marconi, K Frydenvang, TS Thorsen, S Laulumaa, ...
ACS chemical neuroscience 8 (9), 2056-2064, 2017
232017
Discovery of a New Class of Ionotropic Glutamate Receptor Antagonists by the Rational Design of (2S,3R)-3-(3-Carboxyphenyl)-pyrrolidine-2-carboxylic Acid
AM Larsen, R Venskutonyte, EA Valadés, B Nielsen, DS Pickering, ...
ACS Chemical Neuroscience 2 (2), 107-114, 2011
222011
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and …
S Brogi, M Brindisi, S Butini, GU Kshirsagar, S Maramai, G Chemi, ...
Journal of Medicinal Chemistry 61 (5), 2124-2130, 2018
212018
Kainate induces various domain closures in AMPA and kainate receptors
R Venskutonytė, K Frydenvang, H Hald, AC de Rabassa, M Gajhede, ...
Neurochemistry international 61 (4), 536-545, 2012
202012
Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors
L Juknaitė, R Venskutonytė, Z Assaf, S Faure, T Gefflaut, DJ Aitken, ...
Journal of structural biology 180 (1), 39-46, 2012
142012
Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production
R Venskutonytė, A Koh, O Stenström, MT Khan, A Lundqvist, M Akke, ...
Nature communications 12 (1), 1347, 2021
132021
Structural and Pharmacological Characterization of Phenylalanine‐Based AMPA Receptor Antagonists at Kainate Receptors
R Venskutonytė, K Frydenvang, EA Valadés, E Szymańska, TN Johansen, ...
ChemMedChem 7 (10), 1793-1798, 2012
132012
Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2
C Krintel, J Dorosz, AH Larsen, TS Thorsen, R Venskutonytė, O Mirza, ...
The FEBS Journal 288 (3), 995-1007, 2021
122021
Cryo-EM structure supports a role of AQP7 as a junction protein
P Huang, R Venskutonytė, RB Prasad, H Ardalani, SW de Maré, X Fan, ...
Nature Communications 14 (1), 600, 2023
112023
Molecular Recognition of Two 2,4‐syn‐Functionalized (S)‐Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain
R Venskutonytė, AP Larsen, K Frydenvang, M Gajhede, E Sagot, Z Assaf, ...
ChemMedChem 9 (10), 2254-2259, 2014
112014
Small‐molecule positive allosteric modulation of homomeric kainate receptors GluK1‐3: development of screening assays and insight into GluK3 structure
Y Bay, R Venskutonytė, SM Frantsen, TS Thorsen, M Musgaard, ...
The FEBS Journal 291 (7), 1506-1529, 2024
22024
Molecular basis for human aquaporin inhibition
P Huang, H Åbacka, CJ Wilson, ML Wind, M Rűtzler, ...
Proceedings of the National Academy of Sciences 121 (7), e2319682121, 2024
22024
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Artiklar 1–20