An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function D Mateju, TM Franzmann, A Patel, A Kopach, EE Boczek, S Maharana, ... The EMBO journal 36 (12), 1669-1687, 2017 | 452 | 2017 |
Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90 EE Boczek, LG Reefschläger, M Dehling, TJ Struller, E Häusler, A Seidl, ... Proceedings of the National Academy of Sciences 112 (25), E3189-E3198, 2015 | 99 | 2015 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... | 95 | 2019 |
Features of the chaperone cellular network revealed through systematic interaction mapping K Rizzolo, J Huen, A Kumar, S Phanse, J Vlasblom, Y Kakihara, ... Cell reports 20 (11), 2735-2748, 2017 | 66 | 2017 |
Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting B Dreier, G Mikheeva, N Belousova, P Parizek, E Boczek, I Jelesarov, ... Journal of molecular biology 405 (2), 410-426, 2011 | 63 | 2011 |
HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain EE Boczek, J Fürsch, ML Niedermeier, L Jawerth, M Jahnel, M Ruer-Gruß, ... Elife 10, e69377, 2021 | 58 | 2021 |
Hsp90 dependence of a kinase is determined by its conformational landscape Q Luo, EE Boczek, Q Wang, J Buchner, VRI Kaila Scientific reports 7 (1), 43996, 2017 | 29 | 2017 |
Autophosphorylation activates c-Src kinase through global structural rearrangements EE Boczek, Q Luo, M Dehling, M Röpke, SL Mader, A Seidl, VRI Kaila, ... Journal of Biological Chemistry 294 (35), 13186-13197, 2019 | 22 | 2019 |
Phase changes in neurotransmission EE Boczek, S Alberti Science 361 (6402), 548-549, 2018 | 10 | 2018 |
One domain fits all: Using disordered regions to sequester misfolded proteins EE Boczek, S Alberti The Journal of cell biology 217 (4), 1173, 2018 | 8 | 2018 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv. 2019; 721001 RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... Google Scholar][CrossRef][Green Version], 0 | 8 | |
Human small heat shock protein B8 inhibits protein aggregation without affecting the native folding process D Choudhary, L Mediani, MJ Avellaneda, S Bjarnason, S Alberti, ... Journal of the American Chemical Society 145 (28), 15188-15196, 2023 | 4 | 2023 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv: 721001 RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... | 4 | 2019 |
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models H Uechi, S Sridharan, J Nijssen, J Bilstein, JM Iglesias-Artola, S Kishigami, ... bioRxiv, 721001, 2019 | 3 | 2019 |
The first Autumn School on Proteostasis: from molecular mechanisms to organismal consequences E Boczek, G Gaglia, M Olshina, S Sarraf Cell Stress and Chaperones 24 (3), 481-492, 2019 | 2 | 2019 |
Methods of characterizing condensate-associated characteristics of compounds and uses thereof BA Beutel, PJ Dandliker, SP Hale, MA Murcko, EE Boczek, M Mittasch, ... US Patent 11,493,519, 2022 | 1 | 2022 |
Methods of identifying interactions of a compound and a condensate, or a component thereof, and uses thereof DM Mitrea, M Mittasch, PJ Dandliker, BA Beutel, EE Boczek US Patent App. 18/020,897, 2023 | | 2023 |
Methods of characterizing condensate-associated characteristics of compounds and uses thereof BA Beutel, PJ Dandliker, SP Hale, MA Murcko, EE Boczek, M Mittasch, ... US Patent App. 17/960,702, 2023 | | 2023 |
Three complementary mechanisms of quality control ensure RNP granule functionality and dynamics. D Mateju, E Boczek, J Wang, A Kopach, S Maharana, A Patel, HO Lee, ... MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
The maturation of Src kinase by the molecular chaperone Hsp90 and its kinase specific cochaperone Cdc37 E Boczek Technische Universität München, 2015 | | 2015 |