Philippe Sanseau
Philippe Sanseau
Verifierad e-postadress på gsk.com
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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
R Sherrington, EI Rogaev, Y Liang, EA Rogaeva, G Levesque, M Ikeda, ...
Nature 375 (6534), 754-760, 1995
49871995
Drug repurposing: progress, challenges and recommendations
S Pushpakom, F Iorio, PA Eyers, KJ Escott, S Hopper, A Wells, A Doig, ...
Nature reviews Drug discovery 18 (1), 41-58, 2019
10232019
The support of human genetic evidence for approved drug indications
MR Nelson, H Tipney, JL Painter, J Shen, P Nicoletti, Y Shen, A Floratos, ...
Nature genetics 47 (8), 856-860, 2015
7122015
Use of genome-wide association studies for drug repositioning
P Sanseau, P Agarwal, MR Barnes, T Pastinen, JB Richards, LR Cardon, ...
Nature biotechnology 30 (4), 317, 2012
3182012
Computational drug repositioning: from data to therapeutics
MR Hurle, L Yang, Q Xie, DK Rajpal, P Sanseau, P Agarwal
Clinical Pharmacology & Therapeutics 93 (4), 335-341, 2013
2812013
Open Targets: a platform for therapeutic target identification and validation
G Koscielny, P An, D Carvalho-Silva, JA Cham, L Fumis, R Gasparyan, ...
Nucleic acids research 45 (D1), D985-D994, 2017
2642017
Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2
NS Delany, M Hurle, P Facer, T Alnadaf, C Plumpton, IAN Kinghorn, ...
Physiological genomics 4 (3), 165-174, 2001
2432001
Two simple procedures for releasing chromatin from routinely fixed cells for fluorescence in situ hybridization
H Fidlerova, G Senger, M Kost, P Sanseau, D Sheer
Cytogenetic and Genome Research 65 (3), 203-205, 1994
1621994
A computational view of microRNAs and their targets
JR Brown, P Sanseau
Drug Discovery Today 10 (8), 595-601, 2005
1432005
Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs
JR Brown, KK Koretke, ML Birkeland, P Sanseau, DR Patrick
BMC Evolutionary Biology 4 (1), 1-10, 2004
1262004
Rapid in silico cloning of genes using expressed sequence tags (ESTs)
RW Gill, P Sanseau
Elsevier 5, 25-44, 2000
1252000
Cloning of STK13, a Third Human Protein Kinase Related toDrosophilaAurora and Budding Yeast Ipl1 That Maps on Chromosome 19q13. 3–ter
M Bernard, P Sanseau, C Henry, A Couturier, C Prigent
Genomics 53 (3), 406-409, 1998
1141998
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24. 3) associated with familial Alzheimer disease (AD3 locus)
MK Trower, SM Orton, IJ Purvis, P Sanseau, J Riley, C Christodoulou, ...
Proceedings of the National Academy of Sciences 93 (4), 1366-1369, 1996
961996
Evolutionary dynamics of non-coding sequences within the class II region of the human MHC
S Beck, S Abdulla, RP Alderton, RJ Glynne, IG Gut, LK Hosking, ...
Journal of molecular biology 255 (1), 1-13, 1996
951996
Rational drug repositioning by medical genetics
ZY Wang, HY Zhang
Nature biotechnology 31 (12), 1080-1082, 2013
812013
The role of positive selection in determining the molecular cause of species differences in disease
JJ Vamathevan, S Hasan, RD Emes, H Amrine-Madsen, D Rajagopalan, ...
BMC Evolutionary Biology 8 (1), 1-14, 2008
762008
Released chromatin: linearized DNA for high resolution fluorescence in situ hybridization
G Senger, T A. Jones, H Fldlerová, P Sanséau, J Trowsdale, M Duff, ...
Human molecular genetics 3 (8), 1275-1280, 1994
711994
A testis-expressed Zn finger gene (ZNF76) in human 6p21. 3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11
J Ragoussis, G Senger, I Mockridge, P Sanseau, S Ruddy, K Dudley, ...
Genomics 14 (3), 673-679, 1992
631992
Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development
JJ Vamathevan, MD Hall, S Hasan, PM Woollard, M Xu, Y Yang, X Li, ...
Toxicology and applied pharmacology 270 (2), 149-157, 2013
512013
The role of translational bioinformatics in drug discovery
NS Buchan, DK Rajpal, Y Webster, C Alatorre, RC Gudivada, C Zheng, ...
Drug discovery today 16 (9-10), 426-434, 2011
482011
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Artiklar 1–20