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Robert W Myers
Robert W Myers
Independent Consultant: Preclinical Drug Discovery
Verifierad e-postadress på med.cornell.edu
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Role of AMP-activated protein kinase in mechanism of metformin action
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, ...
The Journal of clinical investigation 108 (8), 1167-1174, 2001
67622001
Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase
SJ Darkin-Rattray, AM Gurnett, RW Myers, PM Dulski, TM Crumley, ...
Proceedings of the National Academy of Sciences 93 (23), 13143-13147, 1996
7161996
Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
RW Myers, HP Guan, J Ehrhart, A Petrov, S Prahalada, E Tozzo, X Yang, ...
Science 357 (6350), 507-511, 2017
2552017
The synthesis of 4-methylumbelliferyl α-ketoside of N-acetylneuraminic acid and its use in a fluorometric assay for neuraminidase
RW Myers, RT Lee, YC Lee, GH Thomas, LW Reynolds, Y Uchida
Analytical biochemistry 101 (1), 166-174, 1980
1971980
Mechanism-Based Inhibition of human steroid 5α-reductase by finasteride: Enzyme-catalyzed formation of NADP− dihydrofinasteride, a potent bisubstrate analog inhibitor
HG Bull, M Garcia-Calvo, S Andersson, WF Baginsky, HK Chan, ...
Journal of the American Chemical Society 118 (10), 2359-2365, 1996
1811996
Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes
M Wu, SB Singh, J Wang, CC Chung, G Salituro, BV Karanam, SH Lee, ...
Proceedings of the National Academy of Sciences 108 (13), 5378-5383, 2011
1772011
Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors
AK Ogawa, CA Willoughby, R Bergeron, KP Ellsworth, WM Geissler, ...
Bioorganic & medicinal chemistry letters 13 (20), 3405-3408, 2003
1072003
Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure–activity relationships of apicidin. Part 1
SL Colletti, RW Myers, SJ Darkin-Rattray, AM Gurnett, PM Dulski, ...
Bioorganic & medicinal chemistry letters 11 (2), 107-111, 2001
1052001
Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae.
RW Myers, JW Wray, S Fish, RH Abeles
Journal of Biological Chemistry 268 (33), 24785-24791, 1993
911993
Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure–activity relationships of apicidin. Part 2
SL Colletti, RW Myers, SJ Darkin-Rattray, AM Gurnett, PM Dulski, ...
Bioorganic & medicinal chemistry letters 11 (2), 113-117, 2001
872001
N-Substituted (β-D-galactopyranosylmethyl) amines, and C-β-D-galactopyranosylformamides, and related compounds
JN BeMiller, MP Yadav, VN Kalabokis, RW Myers
Carbohydrate Research 200, 111-126, 1990
811990
Synthesis of apicidin-derived quinolone derivatives: parasite-selective histone deacetylase inhibitors and antiproliferative agents
PT Meinke, SL Colletti, G Doss, RW Myers, AM Gurnett, PM Dulski, ...
Journal of medicinal chemistry 43 (25), 4919-4922, 2000
772000
Synthesis and characterization of some anomeric pairs of per-O-acetylated aldohexopyranosyl cyanides (per-O-acetylated 2, 6-anhydroheptononitriles). On the reaction of per-O …
RW Myers, YC Lee
Carbohydrate research 132 (1), 61-82, 1984
771984
Development of a scintillation proximity assay for histone deacetylase using a biotinylated peptide derived from histone-H4
B Nare, JJ Allocco, R Kuningas, S Galuska, RW Myers, MA Bednarek, ...
Analytical biochemistry 267 (2), 390-396, 1999
731999
Histone deacetylase as target for antiprotozoal agents
PM Dulski, RW Myers, AM Gurnett, SJ Rattray, DM Schmatz
US Patent 6,068,987, 2000
682000
Further studies on the binding characteristics of rabbit liver galactose/N-acetylgalactosamine-specific lectin
RT Lee, RW Myers, YC Lee
Biochemistry 21 (24), 6292-6298, 1982
601982
Novel 3, 4-dihydroquinolin-2 (1H)-one inhibitors of human glycogen phosphorylase a
KG Rosauer, AK Ogawa, CA Willoughby, KP Ellsworth, WM Geissler, ...
Bioorganic & medicinal chemistry letters 13 (24), 4385-4388, 2003
592003
Synthesis of diazomethyl β-D-galactopyranosyl and β-D-glucopyranosyl ketones. Potential affinity-labeling reagents for carbohydrate-binding proteins
RW Myers, YC Lee
Carbohydrate research 152, 143-158, 1986
571986
A new class of glycogen phosphorylase inhibitors
Z Lu, J Bohn, R Bergeron, Q Deng, KP Ellsworth, WM Geissler, G Harris, ...
Bioorganic & medicinal chemistry letters 13 (22), 4125-4128, 2003
512003
Improved preparations of some per-O-acetylated aldohexopyranosyl cyanides
RW Myers, YC Lee
Carbohydrate research 154 (1), 145-163, 1986
441986
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Artiklar 1–20