Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells S Thangamani, HE Eldesouky, H Mohammad, PE Pascuzzi, L Avramova, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1), 3002-3010, 2017 | 115 | 2017 |
Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris HE Eldesouky, X Li, NS Abutaleb, H Mohammad, MN Seleem International journal of antimicrobial agents 52 (6), 754-761, 2018 | 96 | 2018 |
Reversal of azole resistance in Candida albicans by sulfa antibacterial drugs HE Eldesouky, A Mayhoub, TR Hazbun, MN Seleem Antimicrobial Agents and Chemotherapy 62 (3), 10.1128/aac. 00701-17, 2018 | 61 | 2018 |
Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris HE Eldesouky, EA Salama, NA Lanman, TR Hazbun, MN Seleem Antimicrobial agents and chemotherapy 65 (1), 10.1128/aac. 00684-20, 2020 | 48 | 2020 |
Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species HE Eldesouky, EA Salama, X Li, TR Hazbun, AS Mayhoub, MN Seleem Scientific reports 10 (1), 7525, 2020 | 48 | 2020 |
Antibacterial nanotruffles for treatment of intracellular bacterial infection MG Elnaggar, K Jiang, HE Eldesouky, Y Pei, J Park, SA Yuk, F Meng, ... Biomaterials 262, 120344, 2020 | 44 | 2020 |
Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris H Mohammad, HE Eldesouky, T Hazbun, AS Mayhoub, MN Seleem Scientific reports 9 (1), 18941, 2019 | 42 | 2019 |
Stimulated Raman Imaging Reveals Aberrant Lipogenesis as a Metabolic Marker for Azole-Resistant Candida albicans CW Karanja, W Hong, W Younis, HE Eldesouky, MN Seleem, JX Cheng Analytical chemistry 89 (18), 9822-9829, 2017 | 34 | 2017 |
Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis H Mohammad, NH Elghazawy, HE Eldesouky, YA Hegazy, W Younis, ... ACS infectious Diseases 4 (3), 403-414, 2018 | 33 | 2018 |
Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs HE Eldesouky, NA Lanman, TR Hazbun, MN Seleem Virulence 11 (1), 1466-1481, 2020 | 32 | 2020 |
Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities HE Eldesouky, EA Salama, TR Hazbun, AS Mayhoub, MN Seleem Scientific reports 10 (1), 6089, 2020 | 32 | 2020 |
A library approach to cationic amphiphilic polyproline helices that target intracellular pathogenic bacteria M Nepal, MF Mohamed, R Blade, HE Eldesouky, T N. Anderson, ... ACS Infectious Diseases 4 (9), 1300-1305, 2018 | 16 | 2018 |
Rapid synthesis of bicyclic lactones via palladium-catalyzed aminocarbonylative lactonizations X Yin, H Mohammad, HE Eldesouky, A Abdelkhalek, MN Seleem, M Dai Chemical communications 53 (53), 7238-7241, 2017 | 16 | 2017 |
The evolving biology of Mycobacterium tuberculosis drug resistance RM Jones, KN Adams, HE Eldesouky, DR Sherman Frontiers in cellular and infection microbiology 12, 1027394, 2022 | 15 | 2022 |
Targeting intracellular pathogenic bacteria through n-terminal modification of cationic amphiphilic polyproline helices TA Dietsche, HE Eldesouky, SM Zeiders, MN Seleem, J Chmielewski The Journal of Organic Chemistry 85 (11), 7468-7475, 2020 | 15 | 2020 |
Lopinavir and ritonavir act synergistically with azoles against Candida auris in vitro and in a mouse model of disseminated candidiasis EA Salama, HE Eldesouky, Y Elgammal, NS Abutaleb, MN Seleem International Journal of Antimicrobial Agents 62 (3), 106906, 2023 | 10 | 2023 |
Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic GA Naclerio, NS Abutaleb, KI Onyedibe, C Karanja, HE Eldesouky, ... Journal of medicinal chemistry 65 (9), 6612-6630, 2022 | 9 | 2022 |
Investigation of aryl isonitrile compounds with potent, broad-spectrum antifungal activity H Mohammad, K Kyei-Baffour, W Younis, DC Davis, H Eldesouky, ... Bioorganic & medicinal chemistry 25 (11), 2926-2931, 2017 | 9 | 2017 |
N. Anderson, T.; Seleem, MN; Chmielewski, J., A library approach to cationic amphiphilic polyproline helices that target intracellular pathogenic bacteria M Nepal, MF Mohamed, R Blade, HE Eldesouky ACS Infect. Dis 4 (9), 1300-1305, 2018 | 8 | 2018 |
Non‐Toxic Glycosylated Gold Nanoparticle‐Amphotericin B Conjugates Reduce Biofilms and Intracellular Burden of Fungi and Parasites C Ghosh, S Varela‐Aramburu, HE Eldesouky, S Salehi Hossainy, ... Advanced Therapeutics 4 (5), 2000293, 2021 | 7 | 2021 |