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Hassan Eldesouky
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Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells
S Thangamani, HE Eldesouky, H Mohammad, PE Pascuzzi, L Avramova, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1), 3002-3010, 2017
1032017
Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris
HE Eldesouky, X Li, NS Abutaleb, H Mohammad, MN Seleem
International journal of antimicrobial agents 52 (6), 754-761, 2018
882018
Reversal of azole resistance in Candida albicans by sulfa antibacterial drugs
HE Eldesouky, A Mayhoub, TR Hazbun, MN Seleem
Antimicrobial Agents and Chemotherapy 62 (3), 10.1128/aac. 00701-17, 2018
512018
Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species
HE Eldesouky, EA Salama, X Li, TR Hazbun, AS Mayhoub, MN Seleem
Scientific reports 10 (1), 7525, 2020
382020
Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris
HE Eldesouky, EA Salama, NA Lanman, TR Hazbun, MN Seleem
Antimicrobial agents and chemotherapy 65 (1), 10.1128/aac. 00684-20, 2020
362020
Antibacterial nanotruffles for treatment of intracellular bacterial infection
MG Elnaggar, K Jiang, HE Eldesouky, Y Pei, J Park, SA Yuk, F Meng, ...
Biomaterials 262, 120344, 2020
352020
Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris
H Mohammad, HE Eldesouky, T Hazbun, AS Mayhoub, MN Seleem
Scientific reports 9 (1), 18941, 2019
332019
Stimulated Raman Imaging Reveals Aberrant Lipogenesis as a Metabolic Marker for Azole-Resistant Candida albicans
CW Karanja, W Hong, W Younis, HE Eldesouky, MN Seleem, JX Cheng
Analytical chemistry 89 (18), 9822-9829, 2017
322017
Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis
H Mohammad, NH Elghazawy, HE Eldesouky, YA Hegazy, W Younis, ...
ACS infectious Diseases 4 (3), 403-414, 2018
302018
Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities
HE Eldesouky, EA Salama, TR Hazbun, AS Mayhoub, MN Seleem
Scientific reports 10 (1), 6089, 2020
272020
Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs
HE Eldesouky, NA Lanman, TR Hazbun, MN Seleem
Virulence 11 (1), 1466-1481, 2020
242020
Rapid synthesis of bicyclic lactones via palladium-catalyzed aminocarbonylative lactonizations
X Yin, H Mohammad, HE Eldesouky, A Abdelkhalek, MN Seleem, M Dai
Chemical communications 53 (53), 7238-7241, 2017
152017
Targeting intracellular pathogenic bacteria through n-terminal modification of cationic amphiphilic polyproline helices
TA Dietsche, HE Eldesouky, SM Zeiders, MN Seleem, J Chmielewski
The Journal of Organic Chemistry 85 (11), 7468-7475, 2020
112020
A library approach to cationic amphiphilic polyproline helices that target intracellular pathogenic bacteria
M Nepal, MF Mohamed, R Blade, HE Eldesouky, T N. Anderson, ...
ACS Infectious Diseases 4 (9), 1300-1305, 2018
112018
Investigation of aryl isonitrile compounds with potent, broad-spectrum antifungal activity
H Mohammad, K Kyei-Baffour, W Younis, DC Davis, H Eldesouky, ...
Bioorganic & medicinal chemistry 25 (11), 2926-2931, 2017
92017
The evolving biology of Mycobacterium tuberculosis drug resistance
HEEDRS Richard M. Jones, Kristin N. Adams
Front. Cell. Infect. Microbiol, 2022
72022
Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic
GA Naclerio, NS Abutaleb, KI Onyedibe, C Karanja, HE Eldesouky, ...
Journal of medicinal chemistry 65 (9), 6612-6630, 2022
62022
Non‐Toxic Glycosylated Gold Nanoparticle‐Amphotericin B Conjugates Reduce Biofilms and Intracellular Burden of Fungi and Parasites
C Ghosh, S Varela‐Aramburu, HE Eldesouky, S Salehi Hossainy, ...
Advanced Therapeutics 4 (5), 2000293, 2021
62021
Lopinavir and ritonavir act synergistically with azoles against Candida auris in vitro and in a mouse model of disseminated candidiasis
EA Salama, HE Eldesouky, Y Elgammal, NS Abutaleb, MN Seleem
International Journal of Antimicrobial Agents 62 (3), 106906, 2023
42023
Fingerprint Stimulated Raman Scattering Imaging Unveils Ergosteryl Ester as a Metabolic Signature of Azole-Resistant Candida albicans
M Zhang, PT Dong, HE Eldesouky, Y Zhan, H Lin, Z Wang, EA Salama, ...
Analytical Chemistry 95 (26), 9901-9913, 2023
22023
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Articles 1–20