Novel gold (I) complexes with 5-phenyl-1, 3, 4-oxadiazole-2-thione and phosphine as potential anticancer and antileishmanial agents JDS Chaves, LG Tunes, CHJ Franco, TM Francisco, CC Corrêa, ... European journal of medicinal chemistry 127, 727-739, 2017 | 62 | 2017 |
Novel antitumor adamantane–azole gold (I) complexes as potential inhibitors of thioredoxin reductase A Garcia, RC Machado, RM Grazul, MTP Lopes, CC Corrêa, ... JBIC Journal of Biological Inorganic Chemistry 21, 275-292, 2016 | 58 | 2016 |
Synthesis and anticancer evaluation of new lipophilic 1, 2, 4 and 1, 3, 4-oxadiazoles W Caneschi, KB Enes, CC de Mendonça, F de Souza Fernandes, ... European journal of medicinal chemistry 165, 18-30, 2019 | 56 | 2019 |
Heparan sulfate proteoglycan-mediated entry pathway for charged tri-platinum compounds: differential cellular accumulation mechanisms for platinum H Silva, F Frézard, EJ Peterson, P Kabolizadeh, JJ Ryan, NP Farrell Molecular pharmaceutics 9 (6), 1795-1802, 2012 | 46 | 2012 |
Synthesis and cytotoxic activity of gold (I) complexes containing phosphines and 3-benzyl-1, 3-thiazolidine-2-thione or 5-phenyl-1, 3, 4-oxadiazole-2-thione as ligands JDS Chaves, F Neumann, TM Francisco, CC Corrêa, MTP Lopes, H Silva, ... Inorganica Chimica Acta 414, 85-90, 2014 | 44 | 2014 |
Impact of the carbon chain length of novel platinum complexes derived from N-alkyl-propanediamines on their cytotoxic activity and cellular uptake H Silva, CV Barra, CF da Costa, MV de Almeida, ET César, JN Silveira, ... Journal of inorganic biochemistry 102 (4), 767-772, 2008 | 40 | 2008 |
Gold (I) complexes with aryl-thiosemicarbazones: Molecular modeling, synthesis, cytotoxicity and TrxR inhibition TT Tavares, GC Azevedo, A Garcia, AG Carpanez, PM Lewer, D Paschoal, ... Polyhedron 132, 95-104, 2017 | 39 | 2017 |
Preclinical gold complexes as oral drug candidates to treat leishmaniasis are potent trypanothione reductase inhibitors LG Tunes, RE Morato, A Garcia, V Schmitz, M Steindel, JD Corrêa-Junior, ... ACS infectious diseases 6 (5), 1121-1139, 2020 | 36 | 2020 |
Lipophilic gold (I) complexes with 1, 3, 4-oxadiazol-2-thione or 1, 3-thiazolidine-2-thione moieties: synthesis and their cytotoxic and antimicrobial activities AM de Almeida, BA de Oliveira, PP de Castro, CC de Mendonça, ... Biometals 30, 841-857, 2017 | 32 | 2017 |
The anti-Zika virus and anti-tumoral activity of the citrus flavanone lipophilic naringenin-based compounds LA de Oliveira Mendes, CS Ponciano, AHD Cataneo, PF Wowk, ... Chemico-Biological Interactions 331, 109218, 2020 | 31 | 2020 |
Greater binding affinity of trivalent antimony to a CCCH zinc finger domain compared to a CCHC domain of kinetoplastid proteins F Frézard, H Silva, AMC Pimenta, N Farrell, C Demicheli Metallomics 4 (5), 433-440, 2012 | 31 | 2012 |
Platinum (II) and palladium (II) aryl-thiosemicarbazone complexes: synthesis, characterization, molecular modeling, cytotoxicity, and antimicrobial activity TT Tavares, D Paschoal, EVS Motta, AG Carpanez, MTP Lopes, ... Journal of Coordination Chemistry 67 (6), 956-968, 2014 | 29 | 2014 |
Trypanocidal activity of lipophilic diamines and amino alcohols COR Júnior, RO Alves, CAM Rezende, CF Da Costa, H Silva, M Le Hyaric, ... Biomedicine & Pharmacotherapy 64 (9), 624-626, 2010 | 25 | 2010 |
Sonochemical synthesis of highly luminescent silver complexes: Photophysical properties and preliminary in vitro antitumor and antibacterial assays LRV Favarin, LB Oliveira, H Silva, AC Micheletti, L Pizzuti, ... Inorganica Chimica Acta 492, 235-242, 2019 | 23 | 2019 |
New Ru (II)–DMSO complexes containing coumarin-N-acylhydrazone hybrids: Synthesis, X-ray structures, cytotoxicity and antimicrobial activities PSVB de Almeida, TM Pereira, AE Kummerle, GP Guedes, H Silva, ... Polyhedron 171, 20-31, 2019 | 20 | 2019 |
Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone AV Espinosa, DS Costa, LG Tunes, RL Monte‐Neto, RM Grazul, ... Chemical Biology & Drug Design 97 (1), 41-50, 2021 | 15 | 2021 |
Síntese e caracterização de novos complexos de platina (II) com ligantes derivados do furano e nitrofurano W Guerra, APS Fontes, MV Almeida, H Silva Química Nova, 2005 | 15 | 2005 |
Modified pyrazole platinum (II) complex can circumvent albumin and glutathione: Synthesis, structure and cytotoxic activity AL de Andrade Querino, KB Enes, OA Chaves, D Dittz, MRC Couri, ... Bioorganic Chemistry 100, 103936, 2020 | 13 | 2020 |
Synthesis, characterization, cytotoxic and antitubercular activities of new gold (I) and gold (III) complexes containing ligands derived from carbohydrates JDS Chaves, JL Damasceno, MCF Paula, PF de Oliveira, GC Azevedo, ... Biometals 28, 845-860, 2015 | 13 | 2015 |
Novel platinum (II) complexes of long chain aliphatic diamine ligands with oxalato as the leaving group: comparative cytotoxic activity relative to chloride precursors H Silva, CV Barra, FV Rocha, F Frézard, MTP Lopes, APS Fontes Journal of the Brazilian Chemical Society 21, 1961-1967, 2010 | 13 | 2010 |