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Lifeng Yang
Lifeng Yang
Shanghai Institute of Nutrition and Health, Chinese Academy of Science
Verifierad e-postadress på sibs.ac.cn
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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
H Zhao, L Yang, J Baddour, A Achreja, V Bernard, T Moss, JC Marini, ...
elife 5, e10250, 2016
7962016
Glutaminolysis: a hallmark of cancer metabolism
L Yang, S Venneti, D Nagrath
Annual review of biomedical engineering 19, 163-194, 2017
6772017
Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth
L Yang, A Achreja, TL Yeung, LS Mangala, D Jiang, C Han, J Baddour, ...
Cell metabolism 24 (5), 685-700, 2016
3492016
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
L Yang, T Moss, LS Mangala, J Marini, H Zhao, S Wahlig, G Armaiz‐Pena, ...
Molecular systems biology 10 (5), 728, 2014
3412014
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer
P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ...
Nature 542 (7639), 119-123, 2017
2472017
Quantitative fluxomics of circulating metabolites
S Hui, AJ Cowan, X Zeng, L Yang, T TeSlaa, X Li, C Bartman, Z Zhang, ...
Cell metabolism 32 (4), 676-688. e4, 2020
1732020
Serine catabolism feeds NADH when respiration is impaired
L Yang, JCG Canaveras, Z Chen, L Wang, L Liang, C Jang, JA Mayr, ...
Cell metabolism 31 (4), 809-821. e6, 2020
1372020
The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells
K Komurov, JT Tseng, M Muller, EG Seviour, TJ Moss, L Yang, D Nagrath, ...
Molecular systems biology 8 (1), 596, 2012
1282012
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts
TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ...
Elife 8, e50663, 2019
1152019
Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration
CA Caneba, N Bellance, L Yang, L Pabst, D Nagrath
American Journal of Physiology-Endocrinology and Metabolism 303 (8), E1036-E1052, 2012
1082012
Slow TCA flux and ATP production in primary solid tumours but not metastases
CR Bartman, DR Weilandt, Y Shen, WD Lee, Y Han, T TeSlaa, ...
Nature 614 (7947), 349-357, 2023
962023
Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells
CA Caneba, L Yang, J Baddour, R Curtis, J Win, S Hartig, J Marini, ...
Cell death & disease 5 (6), e1302-e1302, 2014
942014
Amplification of USP13 drives ovarian cancer metabolism
C Han, L Yang, HH Choi, J Baddour, A Achreja, Y Liu, Y Li, J Li, G Wan, ...
Nature communications 7 (1), 13525, 2016
892016
Peak annotation and verification engine for untargeted LC–MS metabolomics
L Wang, X Xing, L Chen, L Yang, X Su, H Rabitz, W Lu, JD Rabinowitz
Analytical chemistry 91 (3), 1838-1846, 2018
882018
Mutant Kras-and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma
HQ Ju, H Ying, T Tian, J Ling, J Fu, Y Lu, M Wu, L Yang, A Achreja, ...
Nature communications 8 (1), 14437, 2017
822017
Spatially resolved isotope tracing reveals tissue metabolic activity
L Wang, X Xing, X Zeng, SRE Jackson, T TeSlaa, O Al-Dalahmah, ...
Nature methods 19 (2), 223-230, 2022
792022
Exo-MFA–a 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism
A Achreja, H Zhao, L Yang, TH Yun, J Marini, D Nagrath
Metabolic engineering 43, 156-172, 2017
722017
Role of Increased n-acetylaspartate Levels in Cancer
B Zand, RA Previs, NM Zacharias, R Rupaimoole, T Mitamura, ...
Journal of the National Cancer Institute 108 (6), djv426, 2016
722016
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
L Yang, T TeSlaa, S Ng, M Nofal, L Wang, T Lan, X Zeng, A Cowan, ...
Med 3 (2), 119-136. e8, 2022
512022
Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth
H Zhao, D Teng, L Yang, X Xu, J Chen, T Jiang, AY Feng, Y Zhang, ...
Nature metabolism 4 (12), 1660-1673, 2022
492022
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