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Dr Andrew N Holding
Dr Andrew N Holding
Assistant Professor of Biomedical Science (University of York)
Verifierad e-postadress på york.ac.uk - Startsida
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XL-MS: Protein cross-linking coupled with mass spectrometry
AN Holding
Methods 89, 54-63, 2015
1462015
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
EK Papachristou, K Kishore, AN Holding, K Harvey, TI Roumeliotis, ...
Nature communications 9 (1), 2311, 2018
1222018
Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein
Y Liu, HK Salter, AN Holding, CM Johnson, E Stephens, PJ Lukavsky, ...
Genes & development 27 (11), 1233-1246, 2013
1022013
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), eaar2718, 2018
672018
Organization of subunits in the membrane domain of the bovine F-ATPase revealed by covalent cross-linking
J Lee, SJ Ding, TB Walpole, AN Holding, MG Montgomery, IM Fearnley, ...
Journal of Biological Chemistry 290 (21), 13308-13320, 2015
522015
Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair
A Toste Rêgo, AN Holding, H Kent, MH Lamers
The EMBO journal 32 (9), 1334-1343, 2013
492013
Web tools to fight pandemics: the COVID-19 experience
D Mercatelli, AN Holding, FM Giorgi
Briefings in bioinformatics 22 (2), 690-700, 2021
352021
Conversion of hydroxyphenylpyruvate dioxygenases into hydroxymandelate synthases by directed evolution
HM O’Hare, F Huang, A Holding, OW Choroba, JB Spencer
FEBS letters 580 (14), 3445-3450, 2006
342006
VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer
AN Holding, FM Giorgi, A Donnelly, AE Cullen, S Nagarajan, LA Selth, ...
Genome biology 20 (1), 91, 2019
312019
Hekate: software suite for the mass spectrometric analysis and three-dimensional visualization of cross-linked protein samples
AN Holding, MH Lamers, E Stephens, JM Skehel
Journal of proteome research 12 (12), 5923-5933, 2013
292013
Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq
MJ Guertin, AE Cullen, F Markowetz, AN Holding
Nucleic acids research, 2018
272018
Investigation into the mechanism of phenolic couplings during the biosynthesis of glycopeptide antibiotics
AN Holding, JB Spencer
ChemBioChem 9 (14), 2209-2214, 2008
212008
Genome-wide estrogen receptor-α activation is sustained, not cyclical
AN Holding, AE Cullen, F Markowetz
Elife 7, e40854, 2018
152018
Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
RS Adam, SM van Neerven, C Pleguezuelos-Manzano, S Simmini, ...
Cancer Cell International 20, 1-15, 2020
102020
Novelty in science should not come at the cost of reproducibility
AN Holding
The FEBS Journal 286 (20), 3975-3979, 2019
102019
Detection of subtype-specific breast cancer surface protein biomarkers via a novel transcriptomics approach
D Mercatelli, F Formaggio, M Caprini, A Holding, FM Giorgi
Bioscience Reports 41 (12), BSR20212218, 2021
62021
Data generation and network reconstruction strategies for single cell transcriptomic profiles of CRISPR-mediated gene perturbations
AN Holding, HV Cook, F Markowetz
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (6), 194441, 2020
52020
ZMIZ1 enhances ERα-dependent expression of E2F2 in breast cancer
W Zhao, SF Rose, R Blake, A Godicelj, AE Cullen, J Stenning, L Beevors, ...
Journal of Molecular Endocrinology 1 (aop), 2024
2024
PU. 1 Eviction at Lymphocyte-Specific Chromatin Domains Mediates Glucocorticoid Response in Acute Lymphoblastic Leukemia
D Jing, D Beck, H Cao, F Tian, Y Huang, H Zhao, X Tai, W XU, H Kosasih, ...
2024
Is it possible to measure good science?
AN Holding, KR McIntyre, PT Lynch
The FEBS Journal 290 (8), 2022-2028, 2023
2023
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Artiklar 1–20