Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions C Chu, K Qu, FL Zhong, SE Artandi, HY Chang Molecular cell 44 (4), 667-678, 2011 | 1321 | 2011 |
Physical plasticity of the nucleus in stem cell differentiation JD Pajerowski, KN Dahl, FL Zhong, PJ Sammak, DE Discher Proceedings of the National Academy of Sciences 104 (40), 15619-15624, 2007 | 956 | 2007 |
T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis RC Axtell, BA De Jong, K Boniface, LF Van Der Voort, R Bhat, P De Sarno, ... Nature medicine 16 (4), 406-412, 2010 | 666 | 2010 |
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016 | 391 | 2016 |
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends FL Zhong, LFZ Batista, A Freund, MF Pech, AS Venteicher, SE Artandi Cell 150 (3), 481-494, 2012 | 348 | 2012 |
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita F Zhong, SA Savage, M Shkreli, N Giri, L Jessop, T Myers, R Chen, ... Genes & development 25 (1), 11-16, 2011 | 307 | 2011 |
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells LFZ Batista, MF Pech, FL Zhong, HN Nguyen, KT Xie, AJ Zaug, SM Crary, ... Nature 474 (7351), 399-402, 2011 | 281 | 2011 |
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding FL Zhong, K Robinson, DET Teo, KY Tan, C Lim, CR Harapas, CH Yu, ... Journal of Biological Chemistry 293 (49), 18864-18878, 2018 | 191 | 2018 |
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia KS Robinson, DET Teo, KS Tan, GA Toh, HH Ong, CK Lim, K Lay, BV Au, ... Science 370 (6521), eaay2002, 2020 | 184 | 2020 |
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1 A Freund, FL Zhong, AS Venteicher, Z Meng, TD Veenstra, J Frydman, ... Cell 159 (6), 1389-1403, 2014 | 155 | 2014 |
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 M Huang, X Zhang, GA Toh, Q Gong, J Wang, Z Han, B Wu, F Zhong, ... Nature 592 (7856), 773-777, 2021 | 107 | 2021 |
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis SB Drutman, F Haerynck, FL Zhong, D Hum, NJ Hernandez, S Belkaya, ... Proceedings of the National Academy of Sciences 116 (38), 19055-19063, 2019 | 100 | 2019 |
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells R Planès, M Pinilla, K Santoni, A Hessel, C Passemar, K Lay, P Paillette, ... Molecular cell 82 (13), 2385-2400. e9, 2022 | 81 | 2022 |
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ... Science 377 (6603), 328-335, 2022 | 67 | 2022 |
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ... Nature communications 12 (1), 2130, 2021 | 66 | 2021 |
Structural basis of RIP2 activation and signaling Q Gong, Z Long, FL Zhong, DET Teo, Y Jin, Z Yin, ZZ Boo, Y Zhang, ... Nature communications 9 (1), 4993, 2018 | 66 | 2018 |
Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8 Q Gong, K Robinson, C Xu, PT Huynh, KHC Chong, EYJ Tan, J Zhang, ... Nature communications 12 (1), 188, 2021 | 64 | 2021 |
A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability PH Chia, FL Zhong, S Niwa, C Bonnard, KH Utami, R Zeng, H Lee, ... Elife 7, e32451, 2018 | 60 | 2018 |
Mitochondrial damage activates the NLRP10 inflammasome T Próchnicki, MB Vasconcelos, KS Robinson, MSJ Mangan, D De Graaf, ... Nature immunology 24 (4), 595-603, 2023 | 24 | 2023 |
DPP9 deficiency: an inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling CR Harapas, KS Robinson, K Lay, J Wong, R Moreno Traspas, ... Science immunology 7 (75), eabi4611, 2022 | 24 | 2022 |