| TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013 | 393 | 2013 |
| Poly (dI· dC)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFκB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway … Z Jiang, M Zamanian-Daryoush, H Nie, AM Silva, BRG Williams, X Li Journal of Biological Chemistry 278 (19), 16713-16719, 2003 | 385 | 2003 |
| p38 Mitogen-activated protein kinase-dependent and-independent signaling of mRNA stability of AU-rich element-containing transcripts MAE Frevel, T Bakheet, AM Silva, JG Hissong, KSA Khabar, ... Molecular and cellular biology 23 (2), 425-436, 2003 | 382 | 2003 |
| Intranasal vaccination with messenger RNA as a new approach in gene therapy: use against tuberculosis JCC Lorenzi, APF Trombone, CD Rocha, LP Almeida, RL Lousada, ... BMC biotechnology 10, 1-11, 2010 | 169 | 2010 |
| Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation AM Silva, M Whitmore, Z Xu, Z Jiang, X Li, BRG Williams Journal of Biological Chemistry 279 (36), 37670-37676, 2004 | 128 | 2004 |
| MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection LA de Almeida, NB Carvalho, FS Oliveira, TLS Lacerda, AC Vasconcelos, ... PloS one 6 (8), e23135, 2011 | 94 | 2011 |
| Human cutaneous leishmaniasis: interferon‐dependent expression of double‐stranded RNA‐dependent protein kinase (PKR) via TLR2 A de Carvalho Vivarini, R de Meirelles Santos Pereira, KLD Teixeira, ... The FASEB Journal 25 (12), 4162-4173, 2011 | 73 | 2011 |
| Alternative PCR protocol using a single primer set for assessing DNA quality in several tissues from a large variety of mammalian species living in areas endemic for leishmaniasis EC Ferreira, CM Gontijo, I Cruz, MN Melo, AM Silva Memórias do Instituto Oswaldo Cruz 105, 895-898, 2010 | 64 | 2010 |
| Novel role for the double‐stranded RNA‐activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania RMS Pereira, KL Dias Teixeira, V Barreto‐de‐Souza, TC Calegari‐Silva, ... The FASEB Journal 24 (2), 617-626, 2010 | 63 | 2010 |
| Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice LA de Almeida, GC Macedo, FAV Marinho, MTR Gomes, PP Corsetti, ... Infection and immunity 81 (5), 1654-1662, 2013 | 60 | 2013 |
| Impairment of stress granule assembly via inhibition of the eIF2alpha phosphorylation sensitizes glioma cells to chemotherapeutic agents FAS Vilas-Boas, AM Da Silva, LP de Sousa, KM Lima, JP Vago, ... Journal of neuro-oncology 127, 253-260, 2016 | 59 | 2016 |
| Membrane cholesterol removal changes mechanical properties of cells and induces secretion of a specific pool of lysosomes B Hissa, B Pontes, PMS Roma, AP Alves, CD Rocha, TM Valverde, ... PloS one 8 (12), e82988, 2013 | 59 | 2013 |
| TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-β-dependent signaling in TLR4-mediated responses V Toshchakov, BW Jones, A Lentschat, A Silva, PY Perera, K Thomas, ... Journal of endotoxin research 9 (3), 169-175, 2003 | 55 | 2003 |
| Anti-inflammatory effect of two Lactobacillus strains during infection with Gardnerella vaginalis and Candida albicans in a HeLa cell culture model CMA Santos, MCV Pires, TL Leao, AKS Silva, LS Miranda, FS Martins, ... Microbiology 164 (3), 349-358, 2018 | 48 | 2018 |
| Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner AM Silva, D Wang, AA Komar, BA Castilho, BRG Williams Journal of biological chemistry 282 (14), 10164-10171, 2007 | 44 | 2007 |
| Mice lacking the gamma interferon receptor have an impaired granulomatous reaction to Schistosoma mansoni infection SA Rezende, VR Oliveira, AM Silva, JB Alves, AM Goes, LF Reis Infection and immunity 65 (8), 3457-3461, 1997 | 41 | 1997 |
| Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor WA Andrade, AM Silva, VS Alves, APC Salgado, MB Melo, HM Andrade, ... Genes & Immunity 11 (6), 447-457, 2010 | 32 | 2010 |
| Liver immune cells release type 1 interferon due to DNA sensing and amplify liver injury from acetaminophen overdose AM Araujo, MM Antunes, MS Mattos, AB Diniz, DM Alvarenga, ... Cells 7 (8), 88, 2018 | 30 | 2018 |
| Implication of eIF2α kinase GCN2 in induction of apoptosis and endoplasmic reticulum stress-responsive genes by sodium salicylate SHL Gentz, CM Bertollo, EM Souza-Fagundes, AM da Silva Journal of Pharmacy and Pharmacology 65 (3), 430-440, 2013 | 25 | 2013 |
| Tumour necrosis factor (TNF)‐mediated NF‐κB activation facilitates cellular invasion of non‐professional phagocytic epithelial cell lines by Trypanosoma cruzi AMT Pinto, PCM Sales, ERS Camargos, AM Silva Cellular Microbiology 13 (10), 1518-1529, 2011 | 23 | 2011 |
