Petrus R De Jong
Petrus R De Jong
Celgene
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A gp130–Src–YAP module links inflammation to epithelial regeneration
K Taniguchi, LW Wu, SI Grivennikov, PR De Jong, I Lian, FX Yu, K Wang, ...
Nature 519 (7541), 57-62, 2015
3332015
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells
S Bertin, Y Aoki-Nonaka, PR De Jong, LL Nohara, H Xu, SR Stanwood, ...
Nature immunology 15 (11), 1055-1063, 2014
1362014
Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects
PR de Jong, AWL Schadenberg, NJG Jansen, BJ Prakken
Cell Stress and Chaperones 14 (2), 117-131, 2009
832009
The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1
S Bertin, Y Aoki-Nonaka, J Lee, PR De Jong, P Kim, T Han, T Yu, K To, ...
Gut 66 (9), 1584-1596, 2017
572017
The digestive tract as the origin of systemic inflammation
PR de Jong, JM González-Navajas, NJG Jansen
Critical Care 20 (1), 1-12, 2016
542016
Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis
PR de Jong, N Takahashi, AR Harris, J Lee, S Bertin, J Jeffries, M Jung, ...
The Journal of clinical investigation 124 (9), 3793-3806, 2014
492014
YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis
K Taniguchi, T Moroishi, PR De Jong, M Krawczyk, BM Grebbin, H Luo, ...
Proceedings of the National Academy of Sciences 114 (7), 1643-1648, 2017
452017
TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP
PR de Jong, N Takahashi, M Peiris, S Bertin, J Lee, MG Gareau, ...
Mucosal immunology 8 (3), 491-504, 2015
422015
STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass
PR De Jong, AWL Schadenberg, T Van Den Broek, JM Beekman, ...
PloS one 7 (4), e35070, 2012
402012
Definition of a novel feed-forward mechanism for glycolysis-HIF1α signaling in hypoxic tumors highlights aldolase A as a therapeutic target
G Grandjean, PR De Jong, BP James, MY Koh, R Lemos, J Kingston, ...
Cancer research 76 (14), 4259-4269, 2016
392016
ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation
PR De Jong, K Taniguchi, AR Harris, S Bertin, N Takahashi, J Duong, ...
Nature communications 7 (1), 1-15, 2016
372016
Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP
N Takahashi, Y Matsuda, K Sato, PR De Jong, S Bertin, K Tabeta, ...
Scientific reports 6 (1), 1-11, 2016
272016
STAT3: An anti-invasive factor in colorectal cancer?
PR De Jong, JH Mo, AR Harris, J Lee, E Raz
Cancers 6 (3), 1394-1407, 2014
152014
Differential homeostatic dynamics of human regulatory T-cell subsets following neonatal thymectomy
AWL Schadenberg, T van den Broek, MA Siemelink, SO Algra, ...
Journal of allergy and clinical immunology 133 (1), 277-280. e6, 2014
142014
Novel immune function for the TRPV1 channel in T lymphocytes
S Bertin, PR de Jong, WA Jefferies, E Raz
Channels 8 (6), 479-480, 2014
132014
Generalized tetanus in a 4-year old boy presenting with dysphagia and trismus: a case report
PR De Jong, T de Heer-Groen, CH Schröder, NJG Jansen
Cases Journal 2 (1), 1-4, 2009
102009
Absence of HIF1A Leads to Glycogen Accumulation and an Inflammatory Response That Enables Pancreatic Tumor Growth
M Maruggi, FI Layng, R Lemos, G Garcia, BP James, M Sevilla, ...
Cancer Research 79 (22), 5839-5848, 2019
32019
TRPV1: Turning up the heat on intestinal tumorigenesis
PR de Jong, S Bertin, E Raz
Molecular & cellular oncology 2 (1), e975619, 2015
32015
Pancreatic cancer cell growth requires lipids released by tumor-induced stroma autophagy
PR De Jong, SL Shanahan, MA Brand, AD Campos, A Srirangam, ...
Cancer Research 77 (13 Supplement), 2967-2967, 2017
12017
Pancreatic cancer cells scavenge complex lipids from stroma in the hypoxic tumor microenvironment
PR de Jong, AD Campos, SL Shanahan, AD Richardson, G Powis
Cancer Research 76 (24 Supplement), A25, 2016
12016
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Artiklar 1–20