LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma P Bults, R Bischoff, H Bakker, JA Gietema, NC van de Merbel Analytical chemistry 88 (3), 1871-1877, 2016 | 101 | 2016 |
Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of liquid chromatography coupled to tandem mass spectrometry and ligand binding … P Bults, NC van de Merbel, R Bischoff Expert review of proteomics 12 (4), 355-374, 2015 | 44 | 2015 |
Intact protein bioanalysis by liquid chromatography–high-resolution mass spectrometry P Bults, B Spanov, O Olaleye, NC van de Merbel, R Bischoff Journal of Chromatography B 1110, 155-167, 2019 | 34 | 2019 |
Improving selectivity and sensitivity of protein quantitation by LC–HR–MS/MS: determination of somatropin in rat plasma P Bults, M Meints, A Sonesson, M Knutsson, R Bischoff, ... Bioanalysis 10 (13), 1009-1021, 2018 | 16 | 2018 |
Quantification of surfactant protein D (SPD) in human serum by liquid chromatography-mass spectrometry (LC-MS) F Klont, SD Pouwels, P Bults, NC van de Merbel, NHT Ten Hacken, ... Talanta 202, 507-513, 2019 | 12 | 2019 |
Analytical and pharmacological consequences of the in vivo deamidation of trastuzumab and pertuzumab P Bults, A van der Voort, C Meijer, GS Sonke, R Bischoff, ... Analytical and bioanalytical chemistry, 1-12, 2022 | 9 | 2022 |
Separation of deamidated peptides with mixed-mode chromatography using phospholipid-functionalized monolithic stationary phases C Liu, P Bults, R Bischoff, J Crommen, Q Wang, Z Jiang Journal of Chromatography A 1603, 417-421, 2019 | 9 | 2019 |
Intact protein quantification in biological samples by liquid chromatography–high-resolution mass spectrometry: somatropin in rat plasma P Bults, A Sonesson, M Knutsson, R Bischoff, NC van de Merbel Journal of Chromatography B 1144, 122079, 2020 | 8 | 2020 |
Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients Assessed by Affinity Enrichment and Ion-Exchange Chromatography O Olaleye, B Spanov, P Bults, A van der Voort, N Govorukhina, GS Sonke, ... Drug Metabolism and Disposition 51 (2), 249-256, 2023 | 4 | 2023 |
Pharmacokinetics and biotransformation of biopharmaceuticals: by liquid chromatography with unit-mass and high-resolution mass spectrometric detection P Bults | | 2022 |
Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of LC-MS/MS and ligand binding assays P Bults, NC van de Merbel, R Bischoff Pharmacokinetics and biotransformation of biopharmaceuticals 12 (4), 15, 2022 | | 2022 |
Novel capillary-flow LC HRAM M A Boychenko, P Bults, C Martin Ruehl, F Scientific, G Germany | | |
Novel capillary-flow LC HRAM MS platform for fast targeted analysis and robust profiling of complex samples A Boychenko, P Bults, M Ruehl, C Pynn, M Baynham, W Decrop, A Harder, ... | | |