Douglas A Mitchell
Douglas A Mitchell
Professor of Chemistry, University of Illinois
Verified email at - Homepage
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Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
K Blin, T Wolf, MG Chevrette, X Lu, CJ Schwalen, SA Kautsar, ...
Nucleic acids research 45 (W1), W36-W41, 2017
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine
DA Mitchell, MA Marletta
Nature chemical biology 1 (3), 154-158, 2005
Discovery of a widely distributed toxin biosynthetic gene cluster
SW Lee, DA Mitchell, AL Markley, ME Hensler, D Gonzalez, A Wohlrab, ...
Proceedings of the National Academy of Sciences 105 (15), 5879-5884, 2008
Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors.
JS Lazo, K Nemoto, KE Pestell, K Cooley, EC Southwick, DA Mitchell, ...
Molecular pharmacology 61 (4), 720-728, 2002
A prevalent peptide-binding domain guides ribosomal natural product biosynthesis
BJ Burkhart, GA Hudson, KL Dunbar, DA Mitchell
Nature chemical biology 11 (8), 564-570, 2015
A new genome-mining tool redefines the lasso peptide biosynthetic landscape
JI Tietz, CJ Schwalen, PS Patel, T Maxson, PM Blair, HC Tai, UI Zakai, ...
Nature chemical biology 13 (5), 470-478, 2017
Multitarget drug discovery for tuberculosis and other infectious diseases
K Li, LA Schurig-Briccio, X Feng, A Upadhyay, V Pujari, B Lechartier, ...
Journal of medicinal chemistry 57 (7), 3126-3139, 2014
Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42
R Scholz, KJ Molohon, J Nachtigall, J Vater, AL Markley, RD Süssmuth, ...
Journal of Bacteriology 193 (1), 215-224, 2011
Fe III–TAML-catalyzed green oxidative degradation of the azo dye Orange II by H 2 O 2 and organic peroxides: products, toxicity, kinetics, and mechanisms
N Chahbane, DL Popescu, DA Mitchell, A Chanda, D Lenoir, AD Ryabov, ...
Green Chemistry 9 (1), 49-57, 2007
Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates
JO Melby, NJ Nard, DA Mitchell
Current opinion in chemical biology 15 (3), 369-378, 2011
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells
DA Mitchell, SU Morton, NB Fernhoff, MA Marletta
Proceedings of the National Academy of Sciences 104 (28), 11609-11614, 2007
Catalase− peroxidase activity of iron (III)− TAML activators of hydrogen peroxide
A Ghosh, DA Mitchell, A Chanda, AD Ryabov, DL Popescu, EC Upham, ...
Journal of the American Chemical Society 130 (45), 15116-15126, 2008
Streptolysin S-like virulence factors: the continuing sagA
EM Molloy, PD Cotter, C Hill, DA Mitchell, RP Ross
Nature Reviews Microbiology 9 (9), 670-681, 2011
Subcellular targeting and differential S-nitrosylation of endothelial nitric-oxide synthase
PA Erwin, DA Mitchell, J Sartoretto, MA Marletta, T Michel
Journal of Biological Chemistry 281 (1), 151-157, 2006
YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations
KL Dunbar, JO Melby, DA Mitchell
Nature chemical biology 8 (6), 569-575, 2012
Expansion of ribosomally produced natural products: a nitrile hydratase-and Nif11-related precursor family
DH Haft, MK Basu, DA Mitchell
BMC biology 8 (1), 1-15, 2010
In vitro biosynthesis of the core scaffold of the thiopeptide thiomuracin
GA Hudson, Z Zhang, JI Tietz, DA Mitchell, WA Van Der Donk
Journal of the American Chemical Society 137 (51), 16012-16015, 2015
Antibacterial drug leads targeting isoprenoid biosynthesis
W Zhu, Y Zhang, W Sinko, ME Hensler, J Olson, KJ Molohon, S Lindert, ...
Proceedings of the National Academy of Sciences 110 (1), 123-128, 2013
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