| Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain L Zhan, G Krabbe, F Du, I Jones, MC Reichert, M Telpoukhovskaia, ... PLoS biology 17 (2), e3000134, 2019 | 135 | 2019 |
| Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy C Wang, L Fan, RR Khawaja, B Liu, L Zhan, L Kodama, M Chin, Y Li, D Le, ... Nature communications 13 (1), 1969, 2022 | 128 | 2022 |
| Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy FA Sayed, M Telpoukhovskaia, L Kodama, Y Li, Y Zhou, D Le, A Hauduc, ... Proceedings of the National Academy of Sciences 115 (40), 10172-10177, 2018 | 123 | 2018 |
| Klotho controls the brain–immune system interface in the choroid plexus L Zhu, LR Stein, D Kim, K Ho, GQ Yu, L Zhan, TE Larsson, L Mucke Proceedings of the National Academy of Sciences 115 (48), E11388-E11396, 2018 | 122 | 2018 |
| Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia G Krabbe, SS Minami, JI Etchegaray, P Taneja, B Djukic, D Davalos, D Le, ... Proceedings of the National Academy of Sciences 114 (19), 5029-5034, 2017 | 115 | 2017 |
| Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability NP Shanware, JA Hutchinson, SH Kim, L Zhan, MJ Bowler, RS Tibbetts Journal of Biological Chemistry 286 (14), 12766-12774, 2011 | 102 | 2011 |
| A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states NM Dräger, SM Sattler, CTL Huang, OM Teter, K Leng, SH Hashemi, ... Nature neuroscience 25 (9), 1149-1162, 2022 | 90 | 2022 |
| HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy H Summer, O Li, Q Bao, L Zhan, S Peter, P Sathiyanathan, D Henderson, ... Nucleic acids research 37 (13), 4371-4384, 2009 | 88 | 2009 |
| Microglial microRNAs mediate sex-specific responses to tau pathology L Kodama, E Guzman, JI Etchegaray, Y Li, FA Sayed, L Zhou, Y Zhou, ... Nature neuroscience 23 (2), 167-171, 2020 | 84 | 2020 |
| A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ... Nature neuroscience 26 (3), 416-429, 2023 | 69 | 2023 |
| Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of … L Zhan, Q Xie, RS Tibbetts Human molecular genetics 24 (3), 757-772, 2015 | 68 | 2015 |
| A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain LG Lihong Zhan, Li Fan, Lay Kodama, Peter Dongmin Sohn, Man Ying Wong ... elife, 2020 | 62 | 2020 |
| Identification of genetic modifiers of TDP-43 neurotoxicity in Drosophila L Zhan, KA Hanson, SH Kim, A Tare, RS Tibbetts PloS one 8 (2), e57214, 2013 | 56 | 2013 |
| High-content RNAi screening identifies the Type 1 inositol triphosphate receptor as a modifier of TDP-43 localization and neurotoxicity SH Kim, L Zhan, KA Hanson, RS Tibbetts Human molecular genetics 21 (22), 4845-4856, 2012 | 47 | 2012 |
| Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS SH Kim, SG Stiles, JM Feichtmeier, N Ramesh, L Zhan, MA Scalf, ... Human molecular genetics 27 (2), 322-337, 2018 | 41 | 2018 |
| Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56γ and genotoxic stress NP Shanware, L Zhan, JA Hutchinson, SH Kim, LM Williams, RS Tibbetts PLoS One 5 (8), e12173, 2010 | 33 | 2010 |
| Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia MA Telpoukhovskaia, K Liu, FA Sayed, JI Etchegaray, M Xie, L Zhan, Y Li, ... Scientific reports 10 (1), 13688, 2020 | 17 | 2020 |
| A CRISPRi/a platform in iPSC-derived microglia uncovers regulators of disease states NM Dräger, SM Sattler, CTL Huang, OM Teter, K Leng, SH Hashemi, ... bioRxiv, 2021.06. 16.448639, 2021 | 12 | 2021 |
| Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy. Nat. Commun. 13, 1969 C Wang, L Fan, RR Khawaja, B Liu, L Zhan, L Kodama, M Chin, Y Li, D Le, ... | 9 | 2022 |
| P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING C Clelland, JI Etchegaray, L Kodama, F Sayed, A Sachdev, Y Li, D Le, ... Alzheimer's & Dementia 15, P1509-P1509, 2019 | | 2019 |
Maria A. TelpoukhovskaiaThe Jackson LaboratoryVerified email at jax.org
