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Clotilde Wiel
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Antioxidants can increase melanoma metastasis in mice
K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ...
Science translational medicine 7 (308), 308re8-308re8, 2015
6452015
BACH1 stabilization by antioxidants stimulates lung cancer metastasis
C Wiel, K Le Gal, MX Ibrahim, CA Jahangir, M Kashif, H Yao, DV Ziegler, ...
Cell 178 (2), 330-345. e22, 2019
3982019
Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence
C Wiel, H Lallet-Daher, D Gitenay, B Gras, B Le Calvé, A Augert, ...
Nature communications 5 (1), 3792, 2014
1782014
Histone variant H2A. J accumulates in senescent cells and promotes inflammatory gene expression
K Contrepois, C Coudereau, BA Benayoun, N Schuler, PF Roux, ...
Nature communications 8 (1), 14995, 2017
1682017
Glutamine links obesity to inflammation in human white adipose tissue
P Petrus, S Lecoutre, L Dollet, C Wiel, A Sulen, H Gao, B Tavira, ...
Cell metabolism 31 (2), 375-390. e11, 2020
1612020
Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
DV Ziegler, D Vindrieux, D Goehrig, S Jaber, G Collin, A Griveau, C Wiel, ...
Nature Communications 12 (1), 720, 2021
882021
Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor
JG Christensen, P Olson, T Briere, C Wiel, MO Bergo
Journal of internal medicine 288 (2), 183-191, 2020
832020
PLA2R1 mediates tumor suppression by activating JAK2
D Vindrieux, A Augert, CA Girard, D Gitenay, H Lallet-Daher, C Wiel, ...
Cancer research 73 (20), 6334-6345, 2013
822013
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution.
B Le Calvé, A Griveau, D Vindrieux, R Maréchal, C Wiel, M Svrcek, J Gout, ...
Oncotarget, 2016
662016
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence
D Gitenay, C Wiel, H Lallet-Daher, D Vindrieux, S Aubert, L Payen, ...
Cell death & disease 5 (2), e1089-e1089, 2014
492014
Potassium channel KCNA1 modulates oncogene-induced senescence and transformation
H Lallet-Daher, C Wiel, D Gitenay, N Navaratnam, A Augert, B Le Calvé, ...
Cancer research 73 (16), 5253-5265, 2013
492013
The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes
A Griveau, C Wiel, DV Ziegler, MO Bergo, D Bernard
Aging cell 19 (4), e13122, 2020
432020
Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes
A Griveau, C Wiel, B Le Calvé, DV Ziegler, S Djebali, M Warnier, N Martin, ...
Aging Cell 17 (6), e12835, 2018
332018
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis
C Wiel, A Augert, DF Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, ...
Cell death & disease 4 (10), e855, 2013
322013
The SCN 9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway
M Warnier, JM Flaman, C Chouabe, C Wiel, B Gras, A Griveau, E Blanc, ...
Aging Cell 17 (3), e12736, 2018
252018
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
X Chen, H Yao, M Kashif, G Revêchon, M Eriksson, J Hu, T Wang, Y Liu, ...
Elife 10, e63284, 2021
242021
Mitochondria-targeted antioxidants MitoQ and MitoTEMPO do not influence BRAF-driven malignant melanoma and KRAS-driven lung cancer progression in mice
K Le Gal, C Wiel, MX Ibrahim, M Henricsson, VI Sayin, MO Bergo
Antioxidants 10 (2), 163, 2021
202021
KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer
EA Eklund, C Wiel, H Fagman, LM Akyürek, S Raghavan, J Nyman, ...
Cancers 14 (9), 2063, 2022
182022
Antioxidants promote intestinal tumor progression in mice
ZV Zou, K Le Gal, AE El Zowalaty, LE Pehlivanoglu, V Garellick, N Gul, ...
Antioxidants 10 (2), 241, 2021
182021
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity
L Casares, R Moreno, KX Ali, M Higgins, SD Naidu, G Neill, L Cassin, ...
Redox Biology 51, 102291, 2022
112022
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Artiklar 1–20