Ligand-gated ion channels: mechanisms underlying ion selectivity A Keramidas, AJ Moorhouse, PR Schofield, PH Barry Progress in biophysics and molecular biology 86 (2), 161-204, 2004 | 257 | 2004 |
Taurine is a potent activator of extrasynaptic GABAA receptors in the thalamus F Jia, M Yue, D Chandra, A Keramidas, PA Goldstein, GE Homanics, ... Journal of Neuroscience 28 (1), 106-115, 2008 | 207 | 2008 |
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a IR Chassagnon, CA McCarthy, YKY Chin, SS Pineda, A Keramidas, ... Proceedings of the National Academy of Sciences 114 (14), 3750-3755, 2017 | 197 | 2017 |
M2 pore mutations convert the glycine receptor channel from being anion-to cation-selective A Keramidas, AJ Moorhouse, CR French, PR Schofield, PH Barry Biophysical Journal 79 (1), 247-259, 2000 | 154 | 2000 |
Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity A Keramidas, AJ Moorhouse, KD Pierce, PR Schofield, PH Barry The Journal of general physiology 119 (5), 393-410, 2002 | 113 | 2002 |
GABAA receptor α and γ subunits shape synaptic currents via different mechanisms C Dixon, P Sah, JW Lynch, A Keramidas Journal of Biological Chemistry 289 (9), 5399-5411, 2014 | 101 | 2014 |
Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1 MC Inserra, MR Israel, A Caldwell, J Castro, JR Deuis, AM Harrington, ... Scientific reports 7 (1), 42810, 2017 | 83 | 2017 |
Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation-and anion-selective nAChRs P van Nierop, A Keramidas, S Bertrand, J van Minnen, Y Gouwenberg, ... Journal of Neuroscience 25 (46), 10617-10626, 2005 | 82 | 2005 |
Novel missense mutations in the glycine receptor β subunit gene (GLRB) in startle disease VM James, A Bode, SK Chung, JL Gill, M Nielsen, FM Cowan, M Vujic, ... Neurobiology of disease 52, 137-149, 2013 | 63 | 2013 |
Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels AJ Moorhouse, A Keramidas, A Zaykin, PR Schofield, PH Barry The Journal of general physiology 119 (5), 411-425, 2002 | 48 | 2002 |
New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms A Bode, SE Wood, JGL Mullins, A Keramidas, TD Cushion, RH Thomas, ... Journal of Biological Chemistry 288 (47), 33745-33759, 2013 | 47 | 2013 |
Zolpidem and eszopiclone prime α1β2γ2 GABAA receptors for longer duration of activity CL Dixon, NL Harrison, JW Lynch, A Keramidas British journal of pharmacology 172 (14), 3522-3536, 2015 | 41 | 2015 |
The activation mechanism of α1β2γ2S and α3β3γ2S GABAA receptors A Keramidas, NL Harrison Journal of General Physiology 135 (1), 59-75, 2010 | 41 | 2010 |
An outline of desensitization in pentameric ligand-gated ion channel receptors A Keramidas, JW Lynch Cellular and Molecular Life Sciences 70, 1241-1253, 2013 | 39 | 2013 |
Effects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus M Atif, A Estrada-Mondragon, B Nguyen, JW Lynch, A Keramidas PLoS pathogens 13 (10), e1006663, 2017 | 38 | 2017 |
The contribution of proline 250 (P-2′) to pore diameter and ion selectivity in the human glycine receptor channel DJS Lee, A Keramidas, AJ Moorhouse, PR Schofield, PH Barry Neuroscience letters 351 (3), 196-200, 2003 | 33 | 2003 |
The pre‐M1 segment of the α1 subunit is a transduction element in the activation of the GABAA receptor A Keramidas, TL Kash, NL Harrison The Journal of physiology 575 (1), 11-22, 2006 | 31 | 2006 |
GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance M Atif, JJ Smith, A Estrada-Mondragon, X Xiao, AA Salim, RJ Capon, ... PLoS Pathogens 15 (1), e1007570, 2019 | 30 | 2019 |
Functional reconstitution of glycinergic synapses incorporating defined glycine receptor subunit combinations Y Zhang, CL Dixon, A Keramidas, JW Lynch Neuropharmacology 89, 391-397, 2015 | 30 | 2015 |
Agonist-dependent Single Channel Current and Gating in α4β2δ and α1β2γ2S GABAA Receptors A Keramidas, NL Harrison The Journal of general physiology 131 (2), 163-181, 2008 | 30 | 2008 |