Organoid cultures derived from patients with advanced prostate cancer D Gao, I Vela, A Sboner, PJ Iaquinta, WR Karthaus, A Gopalan, ... Cell 159 (1), 176-187, 2014 | 1460 | 2014 |
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors W Lee, S Teckie, T Wiesner, L Ran, CN Prieto Granada, M Lin, S Zhu, ... Nature genetics 46 (11), 1227-1232, 2014 | 533 | 2014 |
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape C Lu, SU Jain, D Hoelper, D Bechet, RC Molden, L Ran, D Murphy, ... Science 352 (6287), 844-849, 2016 | 374 | 2016 |
Function and molecular mechanism of acetylation in autophagy regulation C Yi, M Ma, L Ran, J Zheng, J Tong, J Zhu, C Ma, Y Sun, S Zhang, ... Science 336 (6080), 474-477, 2012 | 268 | 2012 |
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer T Wiesner, W Lee, AC Obenauf, L Ran, R Murali, QF Zhang, EWP Wong, ... Nature 526 (7573), 453-457, 2015 | 236 | 2015 |
Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth L Ran, I Sirota, Z Cao, D Murphy, Y Chen, S Shukla, Y Xie, MC Kaufmann, ... Cancer discovery 5 (3), 304-315, 2015 | 129 | 2015 |
Spindle cell tumors with RET gene fusions exhibit a morphologic spectrum akin to tumors with NTRK gene fusions CR Antonescu, BC Dickson, D Swanson, L Zhang, YS Sung, YC Kao, ... The American journal of surgical pathology 43 (10), 1384-1391, 2019 | 87 | 2019 |
Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance S Shukla, J Cyrta, DA Murphy, EG Walczak, L Ran, P Agrawal, Y Xie, ... Cancer cell 32 (6), 792-806. e7, 2017 | 75 | 2017 |
GNA11 Q209L mouse model reveals RasGRP3 as an essential signaling node in uveal melanoma AR Moore, L Ran, Y Guan, JJ Sher, TD Hitchman, JQ Zhang, C Hwang, ... Cell reports 22 (9), 2455-2468, 2018 | 72 | 2018 |
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor L Ran, Y Chen, J Sher, EWP Wong, D Murphy, JQ Zhang, D Li, K Deniz, ... Cancer discovery 8 (2), 234-251, 2018 | 57 | 2018 |
Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers A Sheth, S Escobar-Alvarez, J Gardner, L Ran, ML Heaney, ... Cell death & disease 5 (3), e1152-e1152, 2014 | 43 | 2014 |
COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors Y Xie, Z Cao, EWP Wong, Y Guan, W Ma, JQ Zhang, EG Walczak, ... The Journal of clinical investigation 128 (4), 1442-1457, 2018 | 35 | 2018 |
ETV1-Positive Cells Give Rise to BRAFV600E-Mutant Gastrointestinal Stromal Tumors L Ran, D Murphy, J Sher, Z Cao, S Wang, E Walczak, Y Guan, Y Xie, ... Cancer research 77 (14), 3758-3765, 2017 | 16 | 2017 |
Combined inhibition of MAP kinase and KIT signaling effectively destabilizes the ETV1 protein and synergistically suppresses GIST tumorigenesis L Ran, I Sirota, Z Cao, D Murphy, Y Chen, S Shukla, Y Xie, MC Kaufmann, ... Cancer Discov 5, 304-315, 2015 | 4 | 2015 |
Abstract A074: Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance S Shukla, J Cyrta, D Murphy, E Walczak, L Ran, P Agrawal, Y Xie, Y Chen, ... Cancer Research 78 (16_Supplement), A074-A074, 2018 | | 2018 |
Aberrant activation of a gastrointestinal transcriptional circuit in prostate cancer mediates castration resistance. S Shukla, J Cyrta, D Murphy, E Walczak, L Ran, P Agrawal, Y Xie, Y Chen, ... CANCER RESEARCH 78 (16), 65-65, 2018 | | 2018 |
Abstract B13: COP1-ETS axis regulates ERK transcriptional output and modulates sensitivity to MAPK inhibitors Y Xie, Z Cao, WP Wong, Y Guan, J Zhang, E Walczak, D Murphy, L Ran, ... Clinical Cancer Research 24 (2_Supplement), B13-B13, 2018 | | 2018 |
Abstract A15: Modeling sporadic gastrointestinal stromal tumor with BRAFV600E mutation L Ran, D Murphy, J Sher, Z Cao, S Wang, E Walczak, Y Guan, Y Xie, ... Clinical Cancer Research 24 (2_Supplement), A15-A15, 2018 | | 2018 |
Abstract PR12: Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape C Lu, S Jain, D Hoelper, D Bechet, L Ran, I Andrulis, B Dickson, ... Clinical Cancer Research 24 (2_Supplement), PR12-PR12, 2018 | | 2018 |
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. C Lu, S Jain, D Hoelper, D Bechet, L Ran, I Andrulis, B Dickson, ... CLINICAL CANCER RESEARCH 24 (2), 33-33, 2018 | | 2018 |