R Paul Nobrega
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Sub-millisecond time-resolved SAXS using a continuous-flow mixer and X-ray microbeam
R Graceffa, RP Nobrega, RA Barrea, SV Kathuria, S Chakravarthy, ...
Journal of synchrotron radiation 20 (6), 820-825, 2013
Minireview: Structural insights into early folding events using continuous‐flow time‐resolved small‐angle X‐ray scattering
SV Kathuria, L Guo, R Graceffa, R Barrea, RP Nobrega, CR Matthews, ...
Biopolymers 95 (8), 550-558, 2011
Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS
SV Kathuria, C Kayatekin, R Barrea, E Kondrashkina, R Graceffa, L Guo, ...
Journal of molecular biology 426 (9), 1980-1994, 2014
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies
X Lu, RP Nobrega, H Lynaugh, T Jain, K Barlow, T Boland, ...
MAbs 11 (1), 45-57, 2019
Clusters of isoleucine, leucine, and valine side chains define cores of stability in high‐energy states of globular proteins: Sequence determinants of structure and stability
SV Kathuria, YH Chan, RP Nobrega, A Özen, CR Matthews
Protein Science 25 (3), 662-675, 2016
Advances in turbulent mixing techniques to study microsecond protein folding reactions
SV Kathuria, A Chan, R Graceffa, R Paul Nobrega, C Robert Matthews, ...
Biopolymers 99 (11), 888-896, 2013
Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies
R Yang, T Jain, H Lynaugh, RP Nobrega, X Lu, T Boland, I Burnina, T Sun, ...
MAbs 9 (4), 646-653, 2017
Modulation of frustration in folding by sequence permutation
RP Nobrega, K Arora, SV Kathuria, R Graceffa, RA Barrea, L Guo, ...
Proceedings of the National Academy of Sciences 111 (29), 10562-10567, 2014
Understanding ForteBio’s sensors for high-throughput kinetic and epitope screening for purified antibodies and yeast culture supernatant
Y Yu, S Mitchell, H Lynaugh, M Brown, RP Nobrega, X Zhi, T Sun, I Caffry, ...
Journal of biomolecular screening 21 (1), 88-95, 2016
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
S Basak, RP Nobrega, D Tavella, LM Deveau, N Koga, R Tatsumi-Koga, ...
Proceedings of the National Academy of Sciences 116 (14), 6806-6811, 2019
Complementary techniques enhance the quality and scope of information obtained from SAXS
D Lambright, AW Malaby, SV Kathuria, RP Nobrega, O Bilsel, ...
ACA Trans, 1-12, 2013
Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY
J Shi, RP Nobrega, C Schwantes, SV Kathuria, O Bilsel, CR Matthews, ...
Scientific reports 7 (1), 1-13, 2017
Database-Centric Method for Automated High-Throughput Deconvolution and Analysis of Kinetic Antibody Screening Data
RP Nobrega, M Brown, C Williams, C Sumner, P Estep, I Caffry, Y Yu, ...
SLAS TECHNOLOGY: Translating Life Sciences Innovation 22 (5), 547-556, 2017
Early Folding Biases in the Folding Free-Energy Surface of βα-Repeat Proteins: A Dissertation
RP Nobrega
4th International Symposium on Diffraction Structural Biology (ISDSB2013) Fukiage Hall, Nagoya, Japan, 26-29 May 2013
T Yamane, JR Helliwell, JE Johnson, N Yasuoka, N Sakabe
J. Synchrotron Rad 20 (Part 6), 820-825, 2013
Structural analysis of an off-pathway folding intermediate in SpoOF, a CheY-like protein, by HX-MS and mutagenesis: 183
R Nobrega, S Kathuria, GU Zhenyu, R Matthews
Protein Science 18, 116-117, 2009
Advances in turbulent mixing techniques to study...
SV Kathuria, A Chan, R Graceffa, RP Nobrega, CR Matthews, SV Kathuria, ...
Biopolymers 99 (11), 0
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