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Shomit Sengupta
Shomit Sengupta
Senior Director, Atavistik Bio
Verifierad e-postadress på atavistikbio.com
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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ...
Molecular cell 22 (2), 159-168, 2006
32582006
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
S Sengupta, TR Peterson, DM Sabatini
Molecular cell 40 (2), 310-322, 2010
15222010
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ...
Cell 146 (3), 408-420, 2011
13042011
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
ER Flores, KY Tsai, D Crowley, S Sengupta, A Yang, F McKeon, T Jacks
Nature 416 (6880), 560-564, 2002
10422002
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ...
Nature 486 (7404), 490-495, 2012
7642012
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
S Sengupta, TR Peterson, M Laplante, S Oh, DM Sabatini
Nature 468 (7327), 1100-1104, 2010
6742010
Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
ER Flores, S Sengupta, JB Miller, JJ Newman, R Bronson, D Crowley, ...
Cancer cell 7 (4), 363-373, 2005
6362005
Uropathogenic Escherichia coliPotentiates Type 1 Pilus-Induced Apoptosis by Suppressing NF-κB
DJ Klumpp, AC Weiser, S Sengupta, SG Forrestal, RA Batler, ...
Infection and immunity 69 (11), 6689-6695, 2001
1912001
Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis
DJ Klumpp, MT Rycyk, MC Chen, P Thumbikat, S Sengupta, AJ Schaeffer
Infection and immunity 74 (9), 5106-5113, 2006
1262006
Mast cell activation triggers a urothelial inflammatory response mediated by tumor necrosis factor-α
RA Batler, S Sengupta, SG Forrestal, AJ Schaeffer, DJ Klumpp
The Journal of urology 168 (2), 819-825, 2002
582002
Discovery of NV-5138, the first selective Brain mTORC1 activator
S Sengupta, E Giaime, S Narayan, S Hahm, J Howell, D o’Neill, ...
Scientific reports 9 (1), 4107, 2019
532019
Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1–S6K pathway signaling
RA Lindquist, KA Ottina, DB Wheeler, PP Hsu, CC Thoreen, DA Guertin, ...
Genome research 21 (3), 433-446, 2011
482011
Discovery of small-molecule selective mTORC1 inhibitors via direct inhibition of glucose transporters
SA Kang, DJ O'Neill, AW Machl, CJ Lumpkin, SN Galda, S Sengupta, ...
Cell chemical biology 26 (9), 1203-1213. e13, 2019
352019
Modulators of sestrin-GATOR2 interaction and uses thereof
KM Fetalvero, S Narayan, DJ O'neill, E Saiah, S Sengupta
US Patent 10,100,066, 2018
82018
Infectious response to E. coli: molecular and genetic pathways
AJ Schaeffer, DJ Klumpp, AC Weiser, S Sengupta, SG Forrestal, ...
International journal of antimicrobial agents 24, 57-60, 2004
62004
METHODS OF IDENTIFYING MODULATORS OF SESTRIN-GATOR-2 INTERACTION AND USE OF SAME TO MODULATE mTORC1
DM Sabatini, L Chantranupong, RL Wolfson, J Orozco, RA Saxton, ...
US Patent App. 15/511,007, 2017
3*2017
Modulators of sestrin-GATOR2 interaction and uses thereof
KM Fetalvero, S Narayan, DJ O'Neill, E Saiah, S Sengupta
US Patent App. 10/100,066, 2018
1*2018
mTORC1 regulates lipin I localization to control nuclear structure and the SREBP pathway
TR Peterson, S Sengupta, E Harris, A Guertin
BS Biochemistry, 42, 2010
2010
The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease
S Sengupta
Massachusetts Institute of Technology, 2010
2010
Mast cell activation triggers a urothelial inflammatory response mediated by TNF-alpha
RA Batler, S Sengupta, SG Forrestal, AJ Schaeffer, DJ Klumpp
JOURNAL OF UROLOGY 167 (4), 6-7, 2002
2002
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