John Löfblom
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Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications
J Löfblom, J Feldwisch, V Tolmachev, J Carlsson, S Ståhl, FY Frejd
FEBS letters 584 (12), 2670-2680, 2010
Affibody molecules in biotechnological and medical applications
S Ståhl, T Gräslund, AE Karlström, FY Frejd, PÅ Nygren, J Löfblom
Trends in biotechnology 35 (8), 691-712, 2017
Optimizing membrane protein overexpression in the Escherichia coli strain Lemo21 (DE3)
S Schlegel, J Löfblom, C Lee, A Hjelm, M Klepsch, M Strous, D Drew, ...
Journal of molecular biology 423 (4), 648-659, 2012
Optimization of electroporation‐mediated transformation: Staphylococcus carnosus as model organism
J Löfblom, N Kronqvist, M Uhlén, S Ståhl, H Wernérus
Journal of applied microbiology 102 (3), 736-747, 2007
Non-immunoglobulin based protein scaffolds
J Löfblom, FY Frejd, S Ståhl
Current opinion in biotechnology 22 (6), 843-848, 2011
Bacterial display in combinatorial protein engineering
J Löfblom
Biotechnology journal 6 (9), 1115-1129, 2011
Epitope mapping of antibodies using bacterial surface display
J Rockberg, J Löfblom, B Hjelm, M Uhlén, S Ståhl
Nature methods 5 (12), 1039-1045, 2008
A novel affinity protein selection system based on staphylococcal cell surface display and flow cytometry
N Kronqvist, J Löfblom, A Jonsson, H Wernérus, S Ståhl
Protein Engineering, Design & Selection 21 (4), 247-255, 2008
Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules
N Kronqvist, M Malm, L Göstring, E Gunneriusson, M Nilsson, ...
Protein Engineering, Design & Selection 24 (4), 385-396, 2011
Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification
M Malm, N Kronqvist, H Lindberg, L Gudmundsdotter, T Bass, FY Frejd, ...
Plos one 8 (5), e62791, 2013
Surface display of a single-domain antibody library on Gram-positive bacteria
F Fleetwood, N Devoogdt, M Pellis, U Wernery, S Muyldermans, S Ståhl, ...
Cellular and molecular life sciences 70, 1081-1093, 2013
Engineering of bispecific affinity proteins with high affinity for ERBB2 and adaptable binding to albumin
J Nilvebrant, M Åstrand, M Georgieva-Kotseva, M Björnmalm, J Löfblom, ...
PloS one 9 (8), e103094, 2014
Staphylococcus carnosus: from starter culture to protein engineering platform
J Löfblom, R Rosenstein, MT Nguyen, S Ståhl, F Götz
Applied microbiology and biotechnology 101, 8293-8307, 2017
Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin‐binding domain allows for affinity purification and in vivo half‐life extension
M Malm, T Bass, L Gudmundsdotter, M Lord, FY Frejd, S Ståhl, J Löfblom
Biotechnology journal 9 (9), 1215-1222, 2014
Affibody-mediated PET imaging of HER3 expression in malignant tumours
M Rosestedt, KG Andersson, B Mitran, V Tolmachev, J Löfblom, A Orlova, ...
Scientific reports 5 (1), 15226, 2015
Fine affinity discrimination by normalized fluorescence activated cell sorting in staphylococcal surface display
J Löfblom, H Wernérus, S Ståhl
FEMS microbiology letters 248 (2), 189-198, 2005
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3
A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandström, ...
Scientific Reports 9 (1), 9405, 2019
PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR: 2377 affibody molecules
J Garousi, KG Andersson, B Mitran, ML Pichl, S Ståhl, A Orlova, J Löfblom, ...
International journal of oncology 48 (4), 1325-1332, 2016
Engineering bispecificity into a single albumin-binding domain
J Nilvebrant, T Alm, S Hober, J Löfblom
PLoS One 6 (10), e25791, 2011
An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein
J Seijsing, M Lindborg, I Höidén-Guthenberg, H Bönisch, E Guneriusson, ...
Proceedings of the National Academy of Sciences 111 (48), 17110-17115, 2014
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