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Naomi Latorraca
Naomi Latorraca
Verifierad e-postadress på stanford.edu
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GPCR dynamics: structures in motion
NR Latorraca, AJ Venkatakrishnan, RO Dror
Chemical reviews 117 (1), 139-155, 2017
6962017
Structure of the µ-opioid receptor–Gi protein complex
A Koehl, H Hu, S Maeda, Y Zhang, Q Qu, JM Paggi, NR Latorraca, ...
Nature 558 (7711), 547-552, 2018
6022018
Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors
XE Zhou, Y He, PW de Waal, X Gao, Y Kang, N Van Eps, Y Yin, K Pal, ...
Cell 170 (3), 457-469. e13, 2017
3862017
Structure of a signaling cannabinoid receptor 1-G protein complex
KK Kumar, M Shalev-Benami, MJ Robertson, H Hu, SD Banister, ...
Cell 176 (3), 448-458. e12, 2019
3432019
Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc
DP Staus, H Hu, MJ Robertson, ALW Kleinhenz, LM Wingler, WD Capel, ...
Nature 579 (7798), 297-302, 2020
2622020
Angiotensin analogs with divergent bias stabilize distinct receptor conformations
LM Wingler, M Elgeti, D Hilger, NR Latorraca, MT Lerch, DP Staus, ...
Cell 176 (3), 468-478. e11, 2019
2212019
Conformational transitions of a neurotensin receptor 1–Gi1 complex
HE Kato, Y Zhang, H Hu, CM Suomivuori, FMN Kadji, J Aoki, ...
Nature 572 (7767), 80-85, 2019
2112019
Molecular mechanism of GPCR-mediated arrestin activation
NR Latorraca, JK Wang, B Bauer, RJL Townshend, SA Hollingsworth, ...
Nature 557 (7705), 452-456, 2018
1942018
Catalytic activation of β-arrestin by GPCRs
K Eichel, D Jullié, B Barsi-Rhyne, NR Latorraca, M Masureel, JB Sibarita, ...
Nature 557 (7705), 381-386, 2018
1912018
Molecular mechanism of biased signaling in a prototypical G-protein-coupled receptor
CM Suomivuori, NR Latorraca, LM Wingler, S Eismann, MC King, ...
Biophysical Journal 118 (3), 162a, 2020
1802020
Smoothened stimulation by membrane sterols drives Hedgehog pathway activity
I Deshpande, J Liang, D Hedeen, KJ Roberts, Y Zhang, B Ha, ...
Nature 571 (7764), 284-288, 2019
1782019
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
X Liu, S Ahn, AW Kahsai, KC Meng, NR Latorraca, B Pani, ...
Nature 548 (7668), 480-484, 2017
1762017
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR
LM Wingler, MA Skiba, C McMahon, DP Staus, ALW Kleinhenz, ...
Science 367 (6480), 888-892, 2020
1612020
Diverse GPCRs exhibit conserved water networks for stabilization and activation
AJ Venkatakrishnan, AK Ma, R Fonseca, NR Latorraca, B Kelly, RM Betz, ...
Proceedings of the National Academy of Sciences 116 (8), 3288-3293, 2019
1282019
Revealing atomic-level mechanisms of protein allostery with molecular dynamics simulations
S Hertig, NR Latorraca, RO Dror
PLoS computational biology 12 (6), e1004746, 2016
1092016
Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
EM Jones, NB Lubock, AJ Venkatakrishnan, J Wang, AM Tseng, JM Paggi, ...
Elife 9, e54895, 2020
1052020
How GPCR phosphorylation patterns orchestrate arrestin-mediated signaling
NR Latorraca, M Masureel, SA Hollingsworth, FM Heydenreich, ...
Cell 183 (7), 1813-1825. e18, 2020
1042020
Structure and mechanism of the cation–chloride cotransporter NKCC1
TA Chew, BJ Orlando, J Zhang, NR Latorraca, A Wang, SA Hollingsworth, ...
Nature 572 (7770), 488-492, 2019
992019
Mechanism of substrate translocation in an alternating access transporter
NR Latorraca, NM Fastman, AJ Venkatakrishnan, WB Frommer, RO Dror, ...
Cell 169 (1), 96-107. e12, 2017
942017
Gi-and Gs-coupled GPCRs show different modes of G-protein binding
N Van Eps, C Altenbach, LN Caro, NR Latorraca, SA Hollingsworth, ...
Proceedings of the National Academy of Sciences 115 (10), 2383-2388, 2018
842018
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Artiklar 1–20