Structural basis for autoinhibition of Notch WR Gordon, D Vardar-Ulu, G Histen, C Sanchez-Irizarry, JC Aster, ... Nature structural & molecular biology 14 (4), 295-300, 2007 | 460 | 2007 |
Mechanical allostery: evidence for a force requirement in the proteolytic activation of Notch WR Gordon, B Zimmerman, L He, LJ Miles, J Huang, K Tiyanont, ... Developmental cell 33 (6), 729-736, 2015 | 388 | 2015 |
The molecular logic of Notch signaling–a structural and biochemical perspective WR Gordon, KL Arnett, SC Blacklow Journal of cell science 121 (19), 3109-3119, 2008 | 377 | 2008 |
Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3 K Li, Y Li, W Wu, WR Gordon, DW Chang, M Lu, S Scoggin, T Fu, L Vien, ... Journal of Biological Chemistry 283 (12), 8046-8054, 2008 | 273 | 2008 |
Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template EJ Aird, KN Lovendahl, A St. Martin, RS Harris, WR Gordon Communications biology 1 (1), 54, 2018 | 253 | 2018 |
Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL WR Gordon, M Roy, D Vardar-Ulu, M Garfinkel, MR Mansour, JC Aster, ... Blood, The Journal of the American Society of Hematology 113 (18), 4381-4390, 2009 | 217 | 2009 |
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors M Aste-Amézaga, N Zhang, JE Lineberger, BA Arnold, TJ Toner, M Gu, ... PloS one 5 (2), e9094, 2010 | 214 | 2010 |
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ... Nature communications 10 (1), 5222, 2019 | 164 | 2019 |
Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2 WR Gordon, D Vardar-Ulu, S L'Heureux, T Ashworth, MJ Malecki, ... PloS one 4 (8), e6613, 2009 | 125 | 2009 |
Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid WL Ryan, DJ Gordon, DH Levy Journal of the American Chemical Society 124 (21), 6194-6201, 2002 | 88 | 2002 |
Sequence-directed covalent protein–DNA linkages in a single step using HUH-tags KN Lovendahl, AN Hayward, WR Gordon Journal of the American Chemical Society 139 (20), 7030-7035, 2017 | 68 | 2017 |
Electronic Spectroscopy and Photoisomerization of trans-Urocanic Acid in a Supersonic Jet WL Ryan, DH Levy Journal of the American Chemical Society 123 (5), 961-966, 2001 | 45 | 2001 |
The molecular mechanism of Notch activation KN Lovendahl, SC Blacklow, WR Gordon Molecular Mechanisms of Notch Signaling, 47-58, 2018 | 31 | 2018 |
Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering KJ Tompkins, M Houtti, LA Litzau, EJ Aird, BA Everett, AT Nelson, ... Nucleic acids research 49 (2), 1046-1064, 2021 | 28 | 2021 |
Enhanced molecular tension sensor based on bioluminescence resonance energy transfer (BRET) EJ Aird, KJ Tompkins, MP Ramirez, WR Gordon ACS sensors 5 (1), 34-39, 2019 | 27 | 2019 |
Acylation of α-aminoalkyl-copper and cuprate reagents with acid chlorides: Improved yields with soluble copper (I) salts RK Dieter, RR Sharma, W Ryan Tetrahedron letters 38 (5), 783-786, 1997 | 23 | 1997 |
Programmable Assembly of Adeno-Associated Virus–Antibody Composites for Receptor-Mediated Gene Delivery AC Zdechlik, Y He, EJ Aird, WR Gordon, D Schmidt Bioconjugate chemistry 31 (4), 1093-1106, 2019 | 18 | 2019 |
A toolkit for studying cell surface shedding of diverse transmembrane receptors AN Hayward, EJ Aird, WR Gordon Elife 8, e46983, 2019 | 15 | 2019 |
Dystrophin missense mutations alter focal adhesion tension and mechanotransduction MP Ramirez, MJM Anderson, MD Kelly, LJ Sundby, AR Hagerty, ... Proceedings of the National Academy of Sciences 119 (25), e2205536119, 2022 | 14 | 2022 |
Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity BJ Jones, RL Evans III, NJ Mylrea, D Chaudhury, C Luo, B Guan, ... PLoS One 15 (6), e0235341, 2020 | 14 | 2020 |