| Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin RD Morin, NA Johnson, TM Severson, AJ Mungall, J An, R Goya, JE Paul, ... Nature genetics 42 (2), 181-185, 2010 | 1953 | 2010 |
| Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma RD Morin, M Mendez-Lago, AJ Mungall, R Goya, KL Mungall, RD Corbett, ... Nature 476 (7360), 298-303, 2011 | 1864 | 2011 |
| Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution SP Shah, RD Morin, J Khattra, L Prentice, T Pugh, A Burleigh, A Delaney, ... Nature 461 (7265), 809-813, 2009 | 1318 | 2009 |
| Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis KJJ Cheung, NA Johnson, JG Affleck, T Severson, C Steidl, S Ben-Neriah, ... Cancer research 70 (22), 9166-9174, 2010 | 209 | 2010 |
| Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors SJM Jones, J Laskin, YY Li, OL Griffith, J An, M Bilenky, YS Butterfield, ... Genome biology 11, 1-12, 2010 | 200 | 2010 |
| Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer M Michaut, SF Chin, I Majewski, TM Severson, T Bismeijer, L De Koning, ... Scientific reports 6 (1), 1-13, 2016 | 191 | 2016 |
| Prostate cancer reactivates developmental epigenomic programs during metastatic progression MM Pomerantz, X Qiu, Y Zhu, DY Takeda, W Pan, SC Baca, A Gusev, ... Nature genetics 52 (8), 790-799, 2020 | 181 | 2020 |
| Evidence for archaic Asian ancestry on the human X chromosome. HMF Garrigan D, Mobasher Z, Severson T, Wilder JA Mol Biol Evol 22 (22), 189-92, 2005 | 119 | 2005 |
| CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities T Ahrends, J Busselaar, TM Severson, N Bąbała, E de Vries, A Bovens, ... Nature communications 10 (1), 5531, 2019 | 115 | 2019 |
| Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival M Sobral-Leite, K Van de Vijver, M Michaut, R van der Linden, ... Oncoimmunology 7 (12), e1509820, 2018 | 110 | 2018 |
| A novel DNA sequence database for analyzing human demographic history HMF Wall JD, Cox MP, Mendez FL, Woerner A, Severson T Genome Research 18 (8), 1354-61, 2008 | 105 | 2008 |
| ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors K Berns, JJ Caumanns, EM Hijmans, AMC Gennissen, TM Severson, ... Oncogene 37 (33), 4611-4625, 2018 | 92 | 2018 |
| BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential. T Severson, J Peeters, I Majewski, M Magali, A Bosma, S Philip, ... Molecular Oncology 9, 1528-1538, 2015 | 82 | 2015 |
| The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting TM Severson, DM Wolf, C Yau, J Peeters, D Wehkam, PC Schouten, ... Breast Cancer Research 19, 1-9, 2017 | 77 | 2017 |
| PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen … K Beelen, M Opdam, TM Severson, RHT Koornstra, AD Vincent, ... Breast Cancer Research 16, 1-10, 2014 | 76 | 2014 |
| Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome KW McLarren, TM Severson, C du Souich, DW Stockton, LE Kratz, ... The American Journal of Human Genetics 87 (6), 905-914, 2010 | 74 | 2010 |
| DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial DM Wolf, C Yau, A Sanil, A Glas, E Petricoin, J Wulfkuhle, TM Severson, ... NPJ breast cancer 3 (1), 31, 2017 | 69 | 2017 |
| Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer S Zhou, JR Hawley, F Soares, G Grillo, M Teng, SA Madani Tonekaboni, ... Nature communications 11 (1), 441, 2020 | 66 | 2020 |
| The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair AA Shafi, CM McNair, JJ McCann, M Alshalalfa, A Shostak, TM Severson, ... Nature communications 12 (1), 401, 2021 | 63 | 2021 |
| Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across … KN Smitheman, TM Severson, SR Rajapurkar, MT McCabe, N Karpinich, ... haematologica 104 (6), 1156, 2019 | 61 | 2019 |
