| Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis AD Fernandes, JN Reid, JM Macklaim, TA McMurrough, DR Edgell, ... Microbiome 2, 1-13, 2014 | 936 | 2014 |
| Control of catalytic efficiency by a coevolving network of catalytic and noncatalytic residues TA McMurrough, RJ Dickson, SMF Thibert, GB Gloor, DR Edgell Proceedings of the National Academy of Sciences 111 (23), E2376-E2383, 2014 | 35 | 2014 |
| Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases TA McMurrough, CM Brown, K Zhang, G Hausner, MS Junop, GB Gloor, ... Nucleic Acids Research 46 (22), 11990-12007, 2018 | 20 | 2018 |
| Modifying a covarying protein–DNA interaction changes substrate preference of a site-specific endonuclease M Laforet, TA McMurrough, M Vu, CM Brown, K Zhang, MS Junop, ... Nucleic Acids Research 47 (20), 10830-10841, 2019 | 7 | 2019 |
| Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis … AD Fernandes, JN Reid, JM Macklaim, TA McMurrough, DR Edgell, ... | 4 | |
| Lipid-encapsulated dual-cleaving endonuclease for dna and gene editing DR Edgell, TA Mcmurrough, BE Stead, OK Israel US Patent App. 17/514,585, 2022 | 1 | 2022 |
| Harnessing RNA-based DNA repair pathways for targeted gene editing N Huynh, S Kwon, TA McMurrough, KW Loedige, M Tavassoli, W Shao, ... bioRxiv, 2024.04. 09.588775, 2024 | | 2024 |
| Lipid-encapsulated dual-cleaving endonuclease for DNA and gene editing DR Edgell, TA Mcmurrough, BE Stead, OK Israel US Patent 11,814,658, 2023 | | 2023 |
| Coevolving Residues and the Expansion of Substrate Permissibility in LAGLIDADG Homing Endonucleases TA McMurrough The University of Western Ontario (Canada), 2017 | | 2017 |
David R EdgellProfessor of Biochemistry, University of Western Ontario, London ONVerifierad e-postadress på uwo.ca
