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Katarina Gradin
Katarina Gradin
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Year
Hypoxia requires notch signaling to maintain the undifferentiated cell state
MV Gustafsson, X Zheng, T Pereira, K Gradin, S Jin, J Lundkvist, JL Ruas, ...
Developmental cell 9 (5), 617-628, 2005
13312005
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ...
Cancer cell 10 (5), 413-423, 2006
8802006
Activation of hypoxia-inducible factor 1α: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor
PJ Kallio, I Pongratz, K Gradin, J McGuire, L Poellinger
Proceedings of the National Academy of Sciences 94 (11), 5667-5672, 1997
6191997
Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.
K Gradin, J McGuire, RH Wenger, I Kvietikova, R Toftgård, L Tora, ...
Molecular and cellular biology 16 (10), 5221-5231, 1996
5311996
A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors
P Andersson, J McGuire, C Rubio, K Gradin, ML Whitelaw, S Pettersson, ...
Proceedings of the National Academy of Sciences 99 (15), 9990-9995, 2002
3792002
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
X Zheng, S Linke, JM Dias, X Zheng, K Gradin, TP Wallis, BR Hamilton, ...
Proceedings of the National Academy of Sciences 105 (9), 3368-3373, 2008
3062008
Structure and expression of the Ah receptor repressor gene
T Baba, J Mimura, K Gradin, A Kuroiwa, T Watanabe, Y Matsuda, ...
Journal of Biological Chemistry 276 (35), 33101-33110, 2001
2472001
Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism.
A Berghard, K Gradin, I Pongratz, M Whitelaw, L Poellinger
Molecular and cellular biology 13 (1), 677-689, 1993
2251993
Epidermal sensing of oxygen is essential for systemic hypoxic response
AT Boutin, A Weidemann, Z Fu, L Mesropian, K Gradin, C Jamora, ...
Cell 133 (2), 223-234, 2008
1982008
HIF1α delays premature senescence through the activation of MIF
SM Welford, B Bedogni, K Gradin, L Poellinger, MB Powell, AJ Giaccia
Genes & development 20 (24), 3366-3371, 2006
1982006
Induction of ID2 Expression by Hypoxia-inducible Factor-1 A ROLE IN DEDIFFERENTIATION OF HYPOXIC NEUROBLASTOMA CELLS
T Löfstedt, A Jögi, M Sigvardsson, K Gradin, L Poellinger, S Påhlman, ...
Journal of Biological Chemistry 279 (38), 39223-39231, 2004
1692004
The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine
K Gradin, C Takasaki, Y Fujii-Kuriyama, K Sogawa
Journal of Biological Chemistry 277 (26), 23508-23514, 2002
1582002
Complex regulation of the transactivation function of hypoxia-inducible factor-1α by direct interaction with two distinct domains of the CREB-binding protein/p300
JL Ruas, U Berchner-Pfannschmidt, S Malik, K Gradin, J Fandrey, ...
Journal of Biological Chemistry 285 (4), 2601-2609, 2010
972010
Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG–EGFR/ErbB4 autocrine loop
DP Stiehl, MR Bordoli, I Abreu-Rodríguez, K Wollenick, P Schraml, ...
Oncogene 31 (18), 2283-2297, 2012
942012
Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway
AK Peters, S Nijmeijer, K Gradin, M Backlund, A Bergman, L Poellinger, ...
Toxicological Sciences 92 (1), 133-142, 2006
942006
Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway
AK Peters, S Nijmeijer, K Gradin, M Backlund, A Bergman, L Poellinger, ...
Toxicological Sciences 92 (1), 133-142, 2006
942006
Repression of dioxin signal transduction in fibroblasts Identification of a putative repressor associated with Arnt
K Gradin, R Toftgård, L Poellinger, A Berghard
Journal of Biological Chemistry 274 (19), 13511-13518, 1999
891999
Nonresponsiveness of normal human fibroblasts to dioxin correlates with the presence of a constitutive xenobiotic response element-binding factor.
K Gradin, A Wilhelmsson, L Poellinger, A Berghard
Journal of Biological Chemistry 268 (6), 4061-4068, 1993
891993
A tyrosine kinase-dependent pathway regulates ligand-dependent activation of the dioxin receptor in human keratinocytes.
K Gradin, ML Whitelaw, R Toftgård, L Poellinger, A Berghard
Journal of Biological Chemistry 269 (38), 23800-23807, 1994
831994
Serum and extracellular calcium modulate induction of cytochrome P-450IA1 in human keratinocytes.
A Berghard, K Gradin, R Toftgård
Journal of Biological Chemistry 265 (34), 21086-21090, 1990
741990
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