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Jesse Cotari
Jesse Cotari
PhD in Immunology, Cornell University
Verifierad e-postadress på med.cornell.edu
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The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis
Q Chang, E Bournazou, P Sansone, M Berishaj, SP Gao, L Daly, J Wels, ...
Neoplasia 15 (7), 848-IN45, 2013
4842013
Single‐cell quantification of IL‐2 response by effector and regulatory T cells reveals critical plasticity in immune response
O Feinerman, G Jentsch, KE Tkach, JW Coward, MM Hathorn, ...
Molecular systems biology 6 (1), 437, 2010
2362010
Dectin-1 diversifies Aspergillus fumigatus–specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation
A Rivera, TM Hohl, N Collins, I Leiner, A Gallegos, S Saijo, JW Coward, ...
Journal of Experimental Medicine 208 (2), 369-381, 2011
1952011
Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway
J Coward, G Ambrosini, E Musi, JP Truman, A Haimovitz-Friedman, ...
Autophagy 5 (2), 184-193, 2009
1262009
Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780
JS Nair, AL Ho, AN Tse, J Coward, H Cheema, G Ambrosini, N Keen, ...
Molecular biology of the cell 20 (8), 2218-2228, 2009
1122009
Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells
JW Cotari, G Voisinne, OE Dar, V Karabacak, G Altan-Bonnet
Science signaling 6 (266), ra17-ra17, 2013
682013
T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks
KE Tkach, D Barik, G Voisinne, N Malandro, MM Hathorn, JW Cotari, ...
Elife 3, e01944, 2014
672014
Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1
E Romano, JW Cotari, R Barreira da Silva, BC Betts, DJ Chung, ...
Blood, The Journal of the American Society of Hematology 119 (22), 5182-5190, 2012
562012
EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines
D Chakravarty, AM Pedraza, J Cotari, AH Liu, D Punko, A Kokroo, ...
Scientific reports 7 (1), 9043, 2017
372017
Perspectives for computer modeling in the study of T cell activation
J Coward, RN Germain, G Altan-Bonnet
Cold Spring Harbor perspectives in biology 2 (6), a005538, 2010
202010
Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells
ML Palomba, K Piersanti, CGK Ziegler, H Decker, JW Cotari, K Bantilan, ...
PLoS One 9 (1), e79987, 2014
182014
Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death
JW Cotari, G Voisinne, G Altan-Bonnet
Current opinion in biotechnology 24 (4), 760-766, 2013
142013
Dissecting common γ chain cytokine family signaling in T cells using cell-to-cell variability analysis
JW Cotari, G Voisinne, OE Dar, V Karabacak, G Altan-Bonnet
Science signaling 6 (266), ra17, 2013
62013
Tuning of cytokine signaling through imbalanced abundances of receptors and kinases
L Sta, G Voisinne, J Cotari, MF Adamer, C Molina-París, G Altan-Bonnet
bioRxiv, 2022.10. 07.511173, 2022
22022
Safingol, an inhibitor of sphingosine kinase, stimulates autophagy in a ceramide-independent and phosphatidylinositol (PI)-3 kinase-mediated manner
J Coward, JP Truman, G Ambrosini, A Haimovitz-Friedman, GK Schwartz
Cancer Research 65 (9_Supplement), 784-785, 2005
12005
Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of Chronic Lymphocytic Leukemia B cells.
ML Palomba, K Piersanti, CGK Ziegler, J Cotari, R Balderas, SN Malek, ...
Cancer Research 73 (8_Supplement), 2886-2886, 2013
2013
Role of intratumoral cell heterogeneity on therapeutic efficacy in glioblastoma.
D Chakravarty, A Pedraza, AH Liu, J Cotari, G Altan-Bonnet, CW Brennan
Cancer Research 73 (8_Supplement), 4627-4627, 2013
2013
Cell-to-Cell Variability Analysis Dissects the Plasticity of Signaling of
G Altan-Bonnet, JW Cotari, G Voisinne, OE Dar, V Karabacak
Time Integration of Signal Feedbacks Generates Intensive Scaling of Cytokine Regulation
K Tkach, D Barik, M Hathorn, J Cotari, R Vogel, O Krichevsky, ...
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Artiklar 1–19