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Emma Sparr
Emma Sparr
Physical chemistry, Lund university
Verifierad e-postadress på fkem1.lu.se
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Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ...
Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014
6992014
Acceleration of α-synuclein aggregation by exosomes
M Grey, CJ Dunning, R Gaspar, C Grey, P Brundin, E Sparr, S Linse
Journal of Biological Chemistry 290 (5), 2969-2982, 2015
3762015
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ...
Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016
3132016
Islet amyloid polypeptide‐induced membrane leakage involves uptake of lipids by forming amyloid fibers
E Sparr, MFM Engel, DV Sakharov, M Sprong, J Jacobs, B de Kruijff, ...
FEBS letters 577 (1-2), 117-120, 2004
3112004
Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ...
Quarterly reviews of biophysics 50, e6, 2017
2282017
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
2222018
Chemical penetration enhancers in stratum corneum—Relation between molecular effects and barrier function
QD Pham, S Björklund, J Engblom, D Topgaard, E Sparr
Journal of controlled release 232, 175-187, 2016
1942016
Self-association of transmembrane α-helices in model membranes: importance of helix orientation and role of hydrophobic mismatch
E Sparr, WL Ash, PV Nazarov, DTS Rijkers, MA Hemminga, DP Tieleman, ...
Journal of Biological Chemistry 280 (47), 39324-39331, 2005
1662005
Membrane interaction of α-synuclein in different aggregation states
M Grey, S Linse, H Nilsson, P Brundin, E Sparr
Journal of Parkinson's disease 1 (4), 359-371, 2011
1502011
Stratum corneum hydration: phase transformations and mobility in stratum corneum, extracted lipids and isolated corneocytes
CL Silva, D Topgaard, V Kocherbitov, JJS Sousa, AACC Pais, E Sparr
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (11), 2647-2659, 2007
1352007
Skin hydration: interplay between molecular dynamics, structure and water uptake in the stratum corneum
EH Mojumdar, QD Pham, D Topgaard, E Sparr
Scientific reports 7 (1), 15712, 2017
1322017
Membrane lipid co-aggregation with α-synuclein fibrils
E Hellstrand, A Nowacka, D Topgaard, S Linse, E Sparr
PloS one 8 (10), e77235, 2013
1312013
Glycerol and urea can be used to increase skin permeability in reduced hydration conditions
S Björklund, J Engblom, K Thuresson, E Sparr
European Journal of Pharmaceutical Sciences 50 (5), 638-645, 2013
1282013
Ionization Constants pKa of Cardiolipin
G Olofsson, E Sparr
PloS one 8 (9), e73040, 2013
1182013
Development of supramolecular structure through alkylation of pendant pyridyl functionality
EC Constable, CE Housecroft, M Neuburger, D Phillips, PR Raithby, ...
Journal of the Chemical Society, Dalton Transactions, 2219-2228, 2000
1182000
A water gradient can be used to regulate drug transport across skin
S Björklund, J Engblom, K Thuresson, E Sparr
Journal of controlled release 143 (2), 191-200, 2010
1102010
Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics
E Hellstrand, M Grey, ML Ainalem, J Ankner, VT Forsyth, G Fragneto, ...
ACS chemical neuroscience 4 (10), 1339-1351, 2013
1072013
Responding phospholipid membranes—interplay between hydration and permeability
E Sparr, H Wennerström
Biophysical journal 81 (2), 1014-1028, 2001
1062001
Skin membrane electrical impedance properties under the influence of a varying water gradient
S Björklund, T Ruzgas, A Nowacka, I Dahi, D Topgaard, E Sparr, ...
Biophysical journal 104 (12), 2639-2650, 2013
972013
Small polar molecules like glycerol and urea can preserve the fluidity of lipid bilayers under dry conditions
A Nowacka, S Douezan, L Wadsö, D Topgaard, E Sparr
Soft Matter 8 (5), 1482-1491, 2012
932012
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Artiklar 1–20