| A view of the hydrophobic effect NT Southall, KA Dill, ADJ Haymet The Journal of Physical Chemistry B 106 (3), 521-533, 2002 | 1243 | 2002 |
| How ions affect the structure of water B Hribar, NT Southall, V Vlachy, KA Dill Journal of the American Chemical Society 124 (41), 12302-12311, 2002 | 895 | 2002 |
| Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis D Anastasiou, Y Yu, WJ Israelsen, JK Jiang, MB Boxer, BS Hong, ... Nature chemical biology 8 (10), 839-847, 2012 | 810 | 2012 |
| The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics R Huang, N Southall, Y Wang, A Yasgar, P Shinn, A Jadhav, DT Nguyen, ... Science translational medicine 3 (80), 80ps16-80ps16, 2011 | 443 | 2011 |
| Unexplored therapeutic opportunities in the human genome TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ... Nature reviews Drug discovery 17 (5), 317-332, 2018 | 405 | 2018 |
| COPI complex is a regulator of lipid homeostasis M Beller, C Sztalryd, N Southall, M Bell, DS Jä ckle, H., Auld, B Oliver PLoS Biol 6, e292, 2008 | 372 | 2008 |
| A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis M Samie, X Wang, X Zhang, A Goschka, X Li, X Cheng, E Gregg, M Azar, ... Developmental cell 26 (5), 511-524, 2013 | 308 | 2013 |
| Compound cytotoxicity profiling using quantitative high-throughput screening M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ... Environmental health perspectives 116 (3), 284-291, 2008 | 302 | 2008 |
| Fluorescence spectroscopic profiling of compound libraries A Simeonov, A Jadhav, CJ Thomas, Y Wang, R Huang, NT Southall, ... Journal of medicinal chemistry 51 (8), 2363-2371, 2008 | 294 | 2008 |
| Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses JM Jaynes, R Sable, M Ronzetti, W Bautista, Z Knotts, ... Science translational medicine 12 (530), eaax6337, 2020 | 282 | 2020 |
| Pharos: collating protein information to shed light on the druggable genome DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ... Nucleic acids research 45 (D1), D995-D1002, 2017 | 276 | 2017 |
| High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer A Datta, H Kim, L McGee, AE Johnson, S Talwar, J Marugan, N Southall, ... Scientific reports 8 (1), 8161, 2018 | 256 | 2018 |
| The mechanism of hydrophobic solvation depends on solute radius NT Southall, KA Dill The Journal of Physical Chemistry B 104 (6), 1326-1331, 2000 | 254 | 2000 |
| Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation W Wang, Q Gao, M Yang, X Zhang, LU Yu, M Lawas, X Li, ... Proceedings of the National Academy of Sciences 112 (11), E1373-E1381, 2015 | 245 | 2015 |
| The NCATS BioPlanet–an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics R Huang, I Grishagin, Y Wang, T Zhao, J Greene, JC Obenauer, D Ngan, ... Frontiers in pharmacology 10, 445, 2019 | 240 | 2019 |
| Characterization of chemical libraries for luciferase inhibitory activity DS Auld, NT Southall, A Jadhav, RL Johnson, DJ Diller, A Simeonov, ... Journal of medicinal chemistry 51 (8), 2372-2386, 2008 | 239 | 2008 |
| Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ... Cancer cell 24 (1), 90-104, 2013 | 220 | 2013 |
| Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries H Veith, N Southall, R Huang, T James, D Fayne, N Artemenko, M Shen, ... Nature biotechnology 27 (11), 1050-1055, 2009 | 206 | 2009 |
| Evaluation of Substituted N,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase MB Boxer, J Jiang, MG Vander Heiden, M Shen, AP Skoumbourdis, ... Journal of medicinal chemistry 53 (3), 1048-1055, 2010 | 197 | 2010 |
| Discovery, structure–activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase S Patnaik, W Zheng, JH Choi, O Motabar, N Southall, W Westbroek, ... Journal of medicinal chemistry 55 (12), 5734-5748, 2012 | 166 | 2012 |
