| Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers EM Houang, YY Sham, FS Bates, JM Metzger Skeletal muscle 8, 1-19, 2018 | 59 | 2018 |
| Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo EM Houang, KJ Haman, A Filareto, RC Perlingeiro, FS Bates, DA Lowe, ... Molecular Therapy-Methods & Clinical Development 2, 2015 | 54 | 2015 |
| Chemical end group modified diblock copolymers elucidate anchor and chain mechanism of membrane stabilization EM Houang, KJ Haman, M Kim, W Zhang, DA Lowe, YY Sham, TP Lodge, ... Molecular pharmaceutics 14 (7), 2333-2339, 2017 | 39 | 2017 |
| Cardiac muscle membrane stabilization in myocardial reperfusion injury EM Houang, J Bartos, BJ Hackel, TP Lodge, D Yannopoulos, FS Bates, ... JACC: Basic to Translational Science 4 (2), 275-287, 2019 | 34 | 2019 |
| PEO–PPO diblock copolymers protect myoblasts from hypo-osmotic stress in vitro dependent on copolymer size, composition, and architecture M Kim, KJ Haman, EM Houang, W Zhang, D Yannopoulos, JM Metzger, ... Biomacromolecules 18 (7), 2090-2101, 2017 | 31 | 2017 |
| All-atom molecular dynamics-based analysis of membrane-stabilizing copolymer interactions with lipid bilayers probed under constant surface tensions EM Houang, FS Bates, YY Sham, JM Metzger The Journal of Physical Chemistry B 121 (47), 10657-10664, 2017 | 29 | 2017 |
| Pathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations NJ Palpant, EM Houang, W Delport, KEM Hastings, AV Onufriev, ... Physiological genomics 42 (2), 287-299, 2010 | 20 | 2010 |
| Molecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residues BR Thompson, EM Houang, YY Sham, JM Metzger Biophysical journal 106 (10), 2105-2114, 2014 | 18 | 2014 |
| pH-responsive titratable inotropic performance of histidine-modified cardiac troponin I NJ Palpant, EM Houang, YY Sham, JM Metzger Biophysical journal 102 (7), 1570-1579, 2012 | 14 | 2012 |
| The maximal and current accuracy of rigorous protein-ligand binding free energy calculations GA Ross, C Lu, G Scarabelli, SK Albanese, E Houang, R Abel, ED Harder, ... Communications Chemistry 6 (1), 222, 2023 | 13 | 2023 |
| AutoDesigner, a de novo design algorithm for rapidly exploring large chemical space for lead optimization: Application to the design and synthesis of d-amino acid oxidase … PH Bos, EM Houang, F Ranalli, AE Leffler, NA Boyles, VA Eyrich, Y Luria, ... Journal of Chemical Information and Modeling 62 (8), 1905-1915, 2022 | 13 | 2022 |
| Discovery of a Novel Class of d-Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform H Tang, K Jensen, E Houang, FM McRobb, S Bhat, M Svensson, ... Journal of Medicinal Chemistry 65 (9), 6775-6802, 2022 | 11 | 2022 |
| TnI structural interface with the N-terminal lobe of TnC as a determinant of cardiac contractility AD Vetter, EM Houang, JJ Sell, BR Thompson, YY Sham, JM Metzger Biophysical journal 114 (7), 1646-1656, 2018 | 7 | 2018 |
| Copolymer-based membrane stabilizers for Duchenne Muscular Dystrophy E Houang | 3 | 2016 |
| Discovery of a novel class of D-amino acid oxidase (DAO) inhibitors with the Schrödinger computational platform H Tang, K Jensen, E Houang, F McRobb, S Bhat, M Svensson, ... | 1 | 2021 |
| Poloxamer 188 Improves Intra-CPR Hemodynamics and Post-Resuscitation LV Function in a Pig Model of Prolonged Cardiac Arrest T Matsuura, J Bartos, M Sarraf, E Houang, S McKnite, J Rees, D Sloper, ... Circulation 128 (suppl_22), A282-A282, 2013 | 1 | 2013 |
| Heterocyclic compounds and methods of use AM Levinson, E Houang, AE Leffler, A Placzek, A Ruvinsky, ... US Patent App. 18/164,346, 2023 | | 2023 |
| Myoblast Protection by Polyethylene Oxide-Polypropylene Oxide Block Copolymers against Hypo-Osmotic Stress M Kim, K Haman, E Houang, W Zhang, D Yannopoulos, J Metzger, ... Biophysical Journal 114 (3), 360a-361a, 2018 | | 2018 |
| Membrane‐Stabilizing Copolymers Confer Protection to Dystrophic Skeletal Muscle in vitro and in vivo E Houang, K Haman, A Filareto, R Perlingeiro, F Bates, D Lowe, ... The FASEB Journal 29, 1039.3, 2015 | | 2015 |
| Treatment with Poloxamer 188, ischemic postconditioning and sevoflurane in early cardiopulmonary resuscitation after 17 Minutes of cardiac arrest untreated to improve the … N Segal, M Sarraf, TR Matsuura, JA Bartos, ST Youngquist, EM Houang, ... ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION 33, A49-A49, 2014 | | 2014 |
