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Gary Brennan
Gary Brennan
Assistant Professor, University College Dublin
Verifierad e-postadress på ucd.ie
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Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis
RC McKiernan, EM Jimenez-Mateos, I Bray, T Engel, GP Brennan, T Sano, ...
PloS one 7 (5), e35921, 2012
1152012
The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
S McClelland, GP Brennan, C Dubé, S Rajpara, S Iyer, C Richichi, ...
Elife 3, e01267, 2014
1062014
Dual and opposing roles of microRNA-124 in epilepsy are mediated through inflammatory and NRSF-dependent gene networks
GP Brennan, D Dey, Y Chen, KP Patterson, EJ Magnetta, AM Hall, ...
Cell reports 14 (10), 2402-2412, 2016
862016
A microRNA‐129‐5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses
M Rajman, F Metge, R Fiore, S Khudayberdiev, A Aksoy‐Aksel, S Bicker, ...
The EMBO journal 36 (12), 1770-1787, 2017
652017
Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy
R Raoof, S Bauer, H El Naggar, NMC Connolly, GP Brennan, E Brindley, ...
EBioMedicine 38, 127-141, 2018
582018
Rapid, coordinate inflammatory responses after experimental febrile status epilepticus: implications for epileptogenesis
KP Patterson, GP Brennan, M Curran, E Kinney-Lang, C Dubé, F Rashid, ...
Eneuro 2 (5), 2015
502015
Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy
GP Brennan, TZ Baram, NP Poolos
Cold Spring Harbor Perspectives in Medicine, 2016
442016
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo
GP Brennan, EM Jimenez-Mateos, RC McKiernan, T Engel, G Tzivion, ...
PloS one 8 (1), e54491, 2013
432013
microRNAs in the pathophysiology of epilepsy
GP Brennan, DC Henshall
Neuroscience letters 667, 47-52, 2018
412018
MicroRNAs as regulators of brain function and targets for treatment of epilepsy
GP Brennan, DC Henshall
Nature Reviews Neurology 16 (9), 506-519, 2020
392020
Enduring memory impairments provoked by developmental febrile seizures are mediated by functional and structural effects of neuronal restrictive silencing factor
KP Patterson, JM Barry, MM Curran, A Singh-Taylor, G Brennan, ...
Journal of Neuroscience 37 (14), 3799-3812, 2017
332017
A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy
MT Venø, CR Reschke, G Morris, NMC Connolly, J Su, Y Yan, T Engel, ...
Proceedings of the National Academy of Sciences 117 (27), 15977-15988, 2020
252020
A calcium-sensitive feed-forward loop regulating the expression of the ATP-gated purinergic P2X7 receptor via specificity protein 1 and microRNA-22
T Engel, GP Brennan, A Sanz-Rodriguez, M Alves, E Beamer, O Watters, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (2), 255-266, 2017
232017
Antagonizing increased miR-135a levels at the chronic stage of experimental TLE reduces spontaneous recurrent seizures
VR Vangoor, CR Reschke, K Senthilkumar, LL Van De Haar, M De Wit, ...
Journal of Neuroscience 39 (26), 5064-5079, 2019
202019
The role of Sirt1 in epileptogenesis
AM Hall, GP Brennan, TM Nguyen, A Singh-Taylor, HS Mun, MJ Sargious, ...
Eneuro 4 (1), 2017
182017
Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury
T Engel, J Martinez-Villarreal, C Henke, EM Jimenez-Mateos, ...
Molecular neurodegeneration 12 (1), 1-17, 2017
172017
Proteomic analysis of 14-3-3 zeta binding proteins in the mouse hippocampus
M Heverin, GP Brennan, CJ Koehler, A Treumann, DC Henshall
International journal of physiology, pathophysiology and pharmacology 4 (2), 74, 2012
152012
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy
GP Brennan, S Bauer, T Engel, EM Jimenez-Mateos, F Del Gallo, ...
Neurobiology of Disease 144, 105048, 2020
142020
Altered biogenesis and microRNA content of hippocampal exosomes following experimental status epilepticus
A Batool, TDM Hill, NT Nguyen, E Langa, M Diviney, C Mooney, ...
Frontiers in neuroscience 13, 1404, 2020
142020
Spared CA 1 pyramidal neuron function and hippocampal performance following antisense knockdown of micro RNA‐134
G Morris, GP Brennan, CR Reschke, DC Henshall, S Schorge
Epilepsia 59 (8), 1518-1526, 2018
132018
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Artiklar 1–20