Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity J Parcq, T Bertrand, A Montagne, AF Baron, R Macrez, JM Billard, ... Cell Death & Differentiation 19 (12), 1983-1991, 2012 | 67 | 2012 |
Urokinase versus Alteplase for intraventricular hemorrhage fibrinolysis T Gaberel, A Montagne, F Lesept, M Gauberti, E Lemarchand, C Orset, ... Neuropharmacology 85, 158-165, 2014 | 60 | 2014 |
Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors F Lesept, A Chevilley, J Jezequel, L Ladépêche, R Macrez, M Aimable, ... Cell death & disease 7 (11), e2466-e2466, 2016 | 50 | 2016 |
Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR T Bertrand, F Lesept, A Chevilley, S Lenoir, M Aimable, A Briens, ... Cell Death & Disease 6 (10), e1924-e1924, 2015 | 41 | 2015 |
GluN2D subunit-containing NMDA receptors control tissue plasminogen activator-mediated spatial memory P Obiang, R Macrez, A Jullienne, T Bertrand, F Lesept, C Ali, E Maubert, ... Journal of Neuroscience 32 (37), 12726-12734, 2012 | 38 | 2012 |
Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain J Parcq, T Bertrand, AF Baron, Y Hommet, E Anglès-Cano, D Vivien Journal of Thrombosis and Haemostasis 11 (3), 539-546, 2013 | 29 | 2013 |
Impact de la structure de l'activateur tissulaire du plasminogène sur le devenir neuronal: régulation de la signalisation glutamatergique et de l'apoptose T Bertrand Caen, 2014 | | 2014 |
Molecular requirements for a safer generation of thrombolytics by bioengineering the tissue plasminogen activator (TPA) A chain J Parcq, T Bertrand, AF Baron, Y Hommet, E Angles-Cano, D Vivien JOURNAL OF THROMBOSIS AND HAEMOSTASIS 10 (6), E12-E12, 2012 | | 2012 |