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Akul Mehta
Akul Mehta
Harvard Medical School, BIDMC
Verified email at bidmc.harvard.edu
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Cited by
Cited by
Year
GlyGen: computational and informatics resources for glycoscience
WS York, R Mazumder, R Ranzinger, N Edwards, R Kahsay, ...
Glycobiology 30 (2), 72-73, 2020
1412020
Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa
RA Al-Horani, P Ponnusamy, AY Mehta, D Gailani, UR Desai
Journal of medicinal chemistry 56 (3), 867-878, 2013
922013
Rational design of potent, small, synthetic allosteric inhibitors of thrombin
PS Sidhu, A Liang, AY Mehta, MH Abdel Aziz, Q Zhou, UR Desai
Journal of medicinal chemistry 54 (15), 5522-5531, 2011
752011
Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition
PS Sidhu, MH Abdel Aziz, A Sarkar, AY Mehta, Q Zhou, UR Desai
Journal of medicinal chemistry 56 (12), 5059-5070, 2013
632013
Allosterism‐based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα‐binding and heparin‐binding site of thrombin
AY Mehta, BM Mohammed, EJ Martin, DF Brophy, D Gailani, UR Desai
Journal of Thrombosis and Haemostasis 14 (4), 828-838, 2016
482016
GlycoGlyph: a glycan visualizing, drawing and naming application
AY Mehta, RD Cummings
Bioinformatics 36 (11), 3613-3614, 2020
422020
GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays
AY Mehta, RD Cummings
Bioinformatics 35 (18), 3536–3537, 2019
422019
Allosteric partial inhibition of monomeric proteases. Sulfated coumarins induce regulation, not just inhibition, of thrombin
S Verespy III, AY Mehta, D Afosah, RA Al-Horani, UR Desai
Scientific Reports 6 (1), 24043, 2016
402016
Antigenic pressure on H3N2 influenza virus drift strains imposes constraints on binding to sialylated receptors but not phosphorylated glycans
L Byrd-Leotis, C Gao, N Jia, AY Mehta, J Trost, SF Cummings, ...
Journal of virology 93 (22), e01178-19, 2019
352019
Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors
MD Argade, AY Mehta, A Sarkar, UR Desai
Journal of medicinal chemistry 57 (8), 3559-3569, 2014
342014
Interaction of thrombin with sucrose octasulfate
BJ Desai, RS Boothello, AY Mehta, JN Scarsdale, HT Wright, UR Desai
Biochemistry 50 (32), 6973-6982, 2011
342011
Targeting the GPIbα Binding Site of Thrombin To Simultaneously Induce Dual Anticoagulant and Antiplatelet Effects
AY Mehta, JN Thakkar, BM Mohammed, EJ Martin, DF Brophy, ...
Journal of medicinal chemistry 57 (7), 3030-3039, 2014
302014
Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization
AY Mehta, J Heimburg-Molinaro, RD Cummings, CK Goth
Current Opinion in Structural Biology 62, 102-111, 2020
292020
An update on recent patents on thrombin inhibitors (2010-2013)
AY Mehta, Y Jin, UR Desai
Expert opinion on therapeutic patents 24 (1), 47-67, 2014
292014
Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold
RA Al-Horani, AY Mehta, UR Desai
European journal of medicinal chemistry 54, 771-783, 2012
292012
Unique repertoire of anti-carbohydrate antibodies in individual human serum
RND Luetscher, TR McKitrick, C Gao, AY Mehta, AM McQuillan, R Kardish, ...
Scientific reports 10 (1), 15436, 2020
252020
Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity
C Gao, K Stavenhagen, B Eckmair, TR McKitrick, AY Mehta, Y Matsumoto, ...
Science Advances 7 (24), eabf6834, 2021
182021
Novel reversible fluorescent glycan linker for functional glycomics
M Wei, TR McKitrick, AY Mehta, C Gao, N Jia, AM McQuillan, ...
Bioconjugate chemistry 30 (11), 2897-2908, 2019
182019
GlyMDB: Glycan Microarray Database and analysis toolset
Y Cao, SJ Park, AY Mehta, RD Cummings, W Im
Bioinformatics 36 (8), 2438-2442, 2020
172020
Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues
RS Boothello, A Sarkar, VM Tran, TKN Nguyen, NV Sankaranarayanan, ...
ACS chemical biology 10 (6), 1485-1494, 2015
162015
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