GlyGen: computational and informatics resources for glycoscience WS York, R Mazumder, R Ranzinger, N Edwards, R Kahsay, ... Glycobiology 30 (2), 72-73, 2020 | 141 | 2020 |
Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa RA Al-Horani, P Ponnusamy, AY Mehta, D Gailani, UR Desai Journal of medicinal chemistry 56 (3), 867-878, 2013 | 92 | 2013 |
Rational design of potent, small, synthetic allosteric inhibitors of thrombin PS Sidhu, A Liang, AY Mehta, MH Abdel Aziz, Q Zhou, UR Desai Journal of medicinal chemistry 54 (15), 5522-5531, 2011 | 75 | 2011 |
Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition PS Sidhu, MH Abdel Aziz, A Sarkar, AY Mehta, Q Zhou, UR Desai Journal of medicinal chemistry 56 (12), 5059-5070, 2013 | 63 | 2013 |
Allosterism‐based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα‐binding and heparin‐binding site of thrombin AY Mehta, BM Mohammed, EJ Martin, DF Brophy, D Gailani, UR Desai Journal of Thrombosis and Haemostasis 14 (4), 828-838, 2016 | 48 | 2016 |
GlycoGlyph: a glycan visualizing, drawing and naming application AY Mehta, RD Cummings Bioinformatics 36 (11), 3613-3614, 2020 | 42 | 2020 |
GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays AY Mehta, RD Cummings Bioinformatics 35 (18), 3536–3537, 2019 | 42 | 2019 |
Allosteric partial inhibition of monomeric proteases. Sulfated coumarins induce regulation, not just inhibition, of thrombin S Verespy III, AY Mehta, D Afosah, RA Al-Horani, UR Desai Scientific Reports 6 (1), 24043, 2016 | 40 | 2016 |
Antigenic pressure on H3N2 influenza virus drift strains imposes constraints on binding to sialylated receptors but not phosphorylated glycans L Byrd-Leotis, C Gao, N Jia, AY Mehta, J Trost, SF Cummings, ... Journal of virology 93 (22), e01178-19, 2019 | 35 | 2019 |
Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors MD Argade, AY Mehta, A Sarkar, UR Desai Journal of medicinal chemistry 57 (8), 3559-3569, 2014 | 34 | 2014 |
Interaction of thrombin with sucrose octasulfate BJ Desai, RS Boothello, AY Mehta, JN Scarsdale, HT Wright, UR Desai Biochemistry 50 (32), 6973-6982, 2011 | 34 | 2011 |
Targeting the GPIbα Binding Site of Thrombin To Simultaneously Induce Dual Anticoagulant and Antiplatelet Effects AY Mehta, JN Thakkar, BM Mohammed, EJ Martin, DF Brophy, ... Journal of medicinal chemistry 57 (7), 3030-3039, 2014 | 30 | 2014 |
Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization AY Mehta, J Heimburg-Molinaro, RD Cummings, CK Goth Current Opinion in Structural Biology 62, 102-111, 2020 | 29 | 2020 |
An update on recent patents on thrombin inhibitors (2010-2013) AY Mehta, Y Jin, UR Desai Expert opinion on therapeutic patents 24 (1), 47-67, 2014 | 29 | 2014 |
Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold RA Al-Horani, AY Mehta, UR Desai European journal of medicinal chemistry 54, 771-783, 2012 | 29 | 2012 |
Unique repertoire of anti-carbohydrate antibodies in individual human serum RND Luetscher, TR McKitrick, C Gao, AY Mehta, AM McQuillan, R Kardish, ... Scientific reports 10 (1), 15436, 2020 | 25 | 2020 |
Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity C Gao, K Stavenhagen, B Eckmair, TR McKitrick, AY Mehta, Y Matsumoto, ... Science Advances 7 (24), eabf6834, 2021 | 18 | 2021 |
Novel reversible fluorescent glycan linker for functional glycomics M Wei, TR McKitrick, AY Mehta, C Gao, N Jia, AM McQuillan, ... Bioconjugate chemistry 30 (11), 2897-2908, 2019 | 18 | 2019 |
GlyMDB: Glycan Microarray Database and analysis toolset Y Cao, SJ Park, AY Mehta, RD Cummings, W Im Bioinformatics 36 (8), 2438-2442, 2020 | 17 | 2020 |
Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues RS Boothello, A Sarkar, VM Tran, TKN Nguyen, NV Sankaranarayanan, ... ACS chemical biology 10 (6), 1485-1494, 2015 | 16 | 2015 |