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Tobias W. Giessen
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Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation
DT Riglar, TW Giessen, M Baym, SJ Kerns, MJ Niederhuber, RT Bronson, ...
Nature Biotechnology, 2017
3432017
Widespread distribution of encapsulin nanocompartments reveals functional diversity
TW Giessen, PA Silver
Nature Microbiology 2, 17029, 2017
1662017
A catalytic nanoreactor based on in vivo encapsulation of multiple enzymes in an engineered protein nanocompartment
TW Giessen, PA Silver
ChemBioChem, 2016
1282016
Prokaryotic nanocompartments form synthetic organelles in a eukaryote
YH Lau*, TW Giessen*, WJ Altenburg, PA Silver
Nature Communications 9 (1311), *contributed equally, 2018
1232018
Two [4Fe-4S] clusters containing radical SAM enzyme SkfB catalyze thioether bond formation during the maturation of the sporulation killing factor
L Flühe, O Burghaus, BM Wieckowski, TW Giessen, U Linne, ...
Journal of the American Chemical Society 135 (3), 959-962, 2013
1212013
Large protein organelles form a new iron sequestration system with high storage capacity
TW Giessen, BJ Orlando, AA Verdegaal, MG Chambers, J Gardener, ...
eLife, 2019
1082019
Encapsulins: microbial nanocompartments with applications in biomedicine, nanobiotechnology and materials science
TW Giessen
Current Opinion in Chemical Biology 34, 1-10, 2016
1022016
Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity
TW Giessen, MA Marahiel
FEBS letters 586 (15), 2065-2075, 2012
792012
Converting a natural protein compartment into a nanofactory for the size-constrained synthesis of antimicrobial silver nanoparticles
TW Giessen, PA Silver
ACS Synthetic Biology, 2016
772016
Rational and combinatorial tailoring of bioactive cyclic dipeptides
TW Giessen, MA Marahiel
Frontiers in Microbiology 6, 785, 2015
742015
Encapsulation as a strategy for the design of biological compartmentalization
TW Giessen, PA Silver
Journal of Molecular Biology, S0022-2836, 2015
722015
The tRNA-dependent biosynthesis of modified cyclic dipeptides
TW Giessen, MA Marahiel
International journal of molecular sciences 15 (8), 14610-14631, 2014
712014
Insights into the generation of structural diversity in a tRNA-dependent pathway for highly modified bioactive cyclic dipeptides
TW Giessen, AM von Tesmar, MA Marahiel
Chemistry & Biology 20 (6), 828-838, 2013
682013
A tRNA-dependent two-enzyme pathway for the generation of singly and doubly methylated ditryptophan 2, 5-diketopiperazines
TW Giessen, AM von Tesmar, MA Marahiel
Biochemistry 52 (24), 4274-4283, 2013
632013
Advances in Encapsulin Nanocompartment Biology and Engineering
JA Jones, TW Giessen
Biotechnology & Bioengineering, 2020
602020
Isolation, Structure Elucidation, and Biosynthesis of an Unusual Hydroxamic Acid Ester-Containing Siderophore from Actinosynnema mirum
TW Giessen, KB Franke, TA Knappe, FI Kraas, M Bosello, X Xie, U Linne, ...
Journal of natural products 75 (5), 905-914, 2012
572012
Engineering carbon fixation with artificial protein organelles
TW Giessen, PA Silver
Current Opinion in Biotechnology 46, 42-50, 2017
512017
Engineered inter-species amino acid cross-feeding increases population evenness in a synthetic bacterial consortium
M Ziesack, T Gibson, J Oliver, A Shumaker, BB Hsu, D Riglar, TW Giessen, ...
mSystems, 2019
48*2019
Engineering Genetically-Encoded Mineralization and Magnetism via Directed Evolution
X Liu, P Lopez, TW Giessen, M Giles, J Way, PA Silver
Scientific Reports, 2016
472016
A four-enzyme pathway for 3, 5-dihydroxy-4-methylanthranilic acid formation and incorporation into the antitumor antibiotic sibiromycin
TW Giessen, FI Kraas, MA Marahiel
Biochemistry 50 (25), 5680-5692, 2011
432011
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Artiklar 1–20