Niloufar Salehi
Niloufar Salehi
Ph.D. Candidate, Chemical Engineering & Pharmaceutical Sciences, University of Michigan
Verifierad e-postadress på umich.edu
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Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs
B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ...
Molecular pharmaceutics 14 (12), 4281-4294, 2017
582017
Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’project
B Hens, PD Sinko, N Job, M Dean, J Al-Gousous, N Salehi, RM Ziff, ...
International journal of pharmaceutics 548 (1), 120-127, 2018
242018
Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach
P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ...
European Journal of Pharmaceutics and Biopharmaceutics 129, 162-174, 2018
172018
Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate–CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical …
J Al-Gousous, KX Sun, DP McNamara, B Hens, N Salehi, P Langguth, ...
Molecular pharmaceutics 15 (11), 5291-5301, 2018
162018
Mechanistic analysis and experimental verification of bicarbonate-controlled enteric coat dissolution: Potential in vivo implications
J Al-Gousous, H Ruan, JA Blechar, KX Sun, N Salehi, P Langguth, ...
European Journal of Pharmaceutics and Biopharmaceutics 139, 47-58, 2019
152019
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans—Part 1: Fasted State Conditions
M Bermejo, P Paixão, B Hens, Y Tsume, MJ Koenigsknecht, JR Baker, ...
Molecular pharmaceutics 15 (12), 5454-5467, 2018
122018
Mass Transport Analysis of Bicarbonate Buffer: Effect of the CO2–H2CO3 Hydration–Dehydration Kinetics in the Fluid Boundary Layer and the Apparent Effective p K a Controlling …
J Al-Gousous, N Salehi, GE Amidon, RM Ziff, P Langguth, GL Amidon
Molecular pharmaceutics 16 (6), 2626-2635, 2019
92019
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans—Part 2: Fed State
P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ...
Molecular pharmaceutics 15 (12), 5468-5478, 2018
72018
Hierarchical Mass Transfer Analysis of Drug Particle Dissolution, Highlighting the Hydrodynamics, pH, Particle Size, and Buffer Effects for the Dissolution of Ionizable and …
N Salehi, J Al-Gousous, DM Mudie, GL Amidon, RM Ziff, GE Amidon
Molecular Pharmaceutics 17 (10), 3870-3884, 2020
12020
Ultrathin, Large-Area Membrane Diffusion Cell for pH-Dependent Simultaneous Dissolution and Absorption Studies
PD Sinko, S Harris, N Salehi, PJ Meyer, GL Amidon, GE Amidon
Molecular Pharmaceutics 17 (7), 2319-2328, 2020
2020
Mechanistic Mass Transport Modeling of Ionizable Drug Dissolution Under In Vivo-Relevant Buffer and Hydrodynamical Conditions
N Salehi, J Al-Gousous, G Amidon, G Amidon, RM Ziff
2019 AIChE Annual Meeting, 2019
2019
Effect of hydration and dehydration kinetics of the carbonic acid-carbon dioxide interconversion on ionizable solute dissolution in bicarbonate buffer: Hydrodynamics-dependent …
N Salehi, J Al-Gousous, G Amidon, R Ziff, P Langguth, G Amidon
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
pH-Dependent dissolution of enteric polymers: A misconception? Implications for pH-dependent drug delivery
J Al-Gousous, H Ruan, J Blechar, K Sun, N Salehi, P Langguth, N Job, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Summary of the In Vivo Predictive Dissolution (iPD): Oral Drug Delivery (ODD) Conference 2018
B Hens, J Al-Gousous, K Wang, N Salehi, RM Ziff, Y Tsume, M Bermejo, ...
Dissolution Technologies 25 (2), 2018
2018
European Journal of Pharmaceutics and Biopharmaceutics Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi …
P Paixão, M Bermejo, B Hens, Y Tsume, J Dickens, K Shedden, N Salehi, ...
2018
Dynamic Change in pH by Low Buffer Capacity of Gastrointestinal Fluids Along The Human Gastrointestinal Tract: Implications For In Vivo Dissolution and Absorption of Ionizable …
B Hens, Y Tsume, M Bermejo, P Paixão, M Koenigsknecht, J Baker R, ...
Annual AAPS Meeting, Date: 2017/11/12-2017/11/15, Location: San Diego, CA, 2017
2017
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Artiklar 1–16