Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies EM Isin, CS Elmore, GN Nilsson, RA Thompson, L Weidolf Chemical research in toxicology 25 (3), 532-542, 2012 | 257 | 2012 |
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs RA Thompson, EM Isin, Y Li, L Weidolf, K Page, I Wilson, S Swallow, ... Chemical research in toxicology 25 (8), 1616-1632, 2012 | 233 | 2012 |
High‐throughput screening of pKa values of pharmaceuticals by pressure‐assisted capillary electrophoresis and mass spectrometry H Wan, AG Holmén, Y Wang, W Lindberg, M Englund, MB Någård, ... Rapid Communications in Mass Spectrometry 17 (23), 2639-2648, 2003 | 184 | 2003 |
Microbial growth and accumulation in industrial metal-working fluids I Mattsby-Baltzer, M Sandin, B Ahlström, S Allenmark, M Edebo, E Falsen, ... Applied and Environmental Microbiology 55 (10), 2681-2689, 1989 | 179 | 1989 |
In vitro high throughput screening of compounds for favorable metabolic properties in drug discovery. CM Masimirembwa, R Thompson, TB Andersson Combinatorial chemistry & high throughput screening 4 (3), 245-263, 2001 | 168 | 2001 |
Antimicrobial activity of betaine esters, quaternary ammonium amphiphiles which spontaneously hydrolyze into nontoxic components M Lindstedt, S Allenmark, RA Thompson, L Edebo Antimicrobial Agents and Chemotherapy 34 (10), 1949-1954, 1990 | 156 | 1990 |
Reactive Metabolites: Current and Emerging Risk and Hazard Assessments RA Thompson, EM Isin, MO Ogese, JT Mettetal, DP Williams Chemical research in toxicology 29 (4), 505-533, 2016 | 154 | 2016 |
High-pressure liquid chromatographic determination of fungicidal dithiocarbamates KH Gustafsson, RA Thompson Journal of agricultural and food chemistry 29 (4), 729-732, 1981 | 114 | 1981 |
Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development RA Thompson, EM Isin, Y Li, R Weaver, L Weidolf, I Wilson, A Claesson, ... Chemico-biological interactions 192 (1-2), 65-71, 2011 | 99 | 2011 |
The effect of hydrocarbon chain length, pH, and temperature on the binding and bactericidal effect of amphiphilic betaine esters on Salmonella tvphimurium B Ahlström, RA Thompson, L Edebo Apmis 107 (1‐6), 318-324, 1999 | 97 | 1999 |
Hypothesis driven drug design: improving quality and effectiveness of the design-make-test-analyse cycle AT Plowright, C Johnstone, J Kihlberg, J Pettersson, G Robb, ... Drug discovery today 17 (1-2), 56-62, 2012 | 90 | 2012 |
Long-chain alkanoylcholines, a new category of soft antimicrobial agents that are enzymatically degradable B Ahlström, M Chelminska-Bertilsson, RA Thompson, L Edebo Antimicrobial Agents and Chemotherapy 39 (1), 50-55, 1995 | 80 | 1995 |
Factors influencing the micellar catalyzed hydrolysis of long-chain alkyl betainates RA Thompson, S Allenmark Journal of colloid and interface science 148 (1), 241-246, 1992 | 62 | 1992 |
Seasonal, geographic and individual variation of okadaic acid content in cultivated mussels in Sweden L Edebo, S Lange, XP Li, S Allenmark, K Lindgren, R Thompson Apmis 96 (7‐12), 1036-1042, 1988 | 58 | 1988 |
Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases: VII. Sorbents obtained by entrapment of cross-linked bovine serum albumin in … RA Thompson, S Andersson, S Allenmark Journal of Chromatography A 465 (3), 263-270, 1989 | 54 | 1989 |
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists JG Kenna, SH Stahl, JA Eakins, AJ Foster, LC Andersson, J Bergare, ... Journal of Pharmacology and Experimental Therapeutics 352 (2), 281-290, 2015 | 49 | 2015 |
Submicellar complexes may initiate the fungicidal effects of cationic amphiphilic compounds on Candida albicans B Ahlström, M Chelminska-Bertilsson, RA Thompson, L Edebo Antimicrobial agents and chemotherapy 41 (3), 544-550, 1997 | 48 | 1997 |
Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases: IX. Influence of the cross-linking reagent on the retentive and … S Andersson, RA Thompson, SG Allenmark Journal of Chromatography A 591 (1-2), 65-73, 1992 | 45 | 1992 |
N-(9-acridinyl)-bromoacetamide—A powerful reagent for phase-transfer-catalyzed fluorescence labeling of carboxylic acids for liquid chromatography S Allenmark, M Chelminska-Bertilsson, RA Thompson Analytical biochemistry 185 (2), 279-285, 1990 | 44 | 1990 |
Effects of Molecular Association on the Rates of Hydrolysis of Long-Chain Alkyl Betainates (Alkoxycarbonyl-/V, A/,/V-Trialkylmethanaminium Halides) RA Thompson, S Allenmark Acta Chemica Scandinavica 43, 690-693, 1989 | 30 | 1989 |