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Ikuo Kimura
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The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
I Kimura, K Ozawa, D Inoue, T Imamura, K Kimura, T Maeda, K Terasawa, ...
Nature communications 4 (1), 1829, 2013
14242013
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
I Kimura, D Inoue, T Maeda, T Hara, A Ichimura, S Miyauchi, M Kobayashi, ...
Proceedings of the national academy of sciences 108 (19), 8030-8035, 2011
10232011
Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation
M Kasubuchi, S Hasegawa, T Hiramatsu, A Ichimura, I Kimura
Nutrients 7 (4), 2839-2849, 2015
8272015
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
A Ichimura, A Hirasawa, O Poulain-Godefroy, A Bonnefond, T Hara, ...
Nature 483 (7389), 350-354, 2012
7302012
Free fatty acid receptors in health and disease
I Kimura, A Ichimura, R Ohue-Kitano, M Igarashi
Physiological reviews, 2019
6062019
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice
I Kimura, J Miyamoto, R Ohue-Kitano, K Watanabe, T Yamada, M Onuki, ...
Science 367 (6481), eaaw8429, 2020
2932020
The SCFA receptor GPR43 and energy metabolism
I Kimura, D Inoue, K Hirano, G Tsujimoto
Frontiers in endocrinology 5, 93736, 2014
2622014
Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids
J Miyamoto, M Igarashi, K Watanabe, S Karaki, H Mukouyama, S Kishino, ...
Nature communications 10 (1), 4007, 2019
2612019
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway
J Miyamoto, T Mizukure, SB Park, S Kishino, I Kimura, K Hirano, ...
Journal of Biological Chemistry 290 (5), 2902-2918, 2015
2272015
Gut microbiota dysbiosis drives and implies novel therapeutic strategies for diabetes mellitus and related metabolic diseases
X Li, K Watanabe, I Kimura
Frontiers in immunology 8, 318312, 2017
1922017
Nutritional signaling via free fatty acid receptors
J Miyamoto, S Hasegawa, M Kasubuchi, A Ichimura, A Nakajima, I Kimura
International journal of molecular sciences 17 (4), 450, 2016
1902016
Role of free fatty acid receptors in the regulation of energy metabolism
T Hara, D Kashihara, A Ichimura, I Kimura, G Tsujimoto, A Hirasawa
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
1882014
Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders
T Hara, A Hirasawa, A Ichimura, I Kimura, G Tsujimoto
Journal of pharmaceutical sciences 100 (9), 3594-3601, 2011
1872011
GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites
N Morita, E Umemoto, S Fujita, A Hayashi, J Kikuta, I Kimura, T Haneda, ...
Nature 566 (7742), 110-114, 2019
1812019
Free fatty acid receptors as therapeutic targets for the treatment of diabetes
A Ichimura, S Hasegawa, M Kasubuchi, I Kimura
Frontiers in pharmacology 5, 118349, 2014
1792014
Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus
M Doi, A Ishida, A Miyake, M Sato, R Komatsu, F Yamazaki, I Kimura, ...
Nature communications 2 (1), 327, 2011
1552011
Free fatty acid receptors and their role in regulation of energy metabolism
T Hara, I Kimura, D Inoue, A Ichimura, A Hirasawa
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164, 77-116, 2013
1482013
Chemotherapeutic results and prognostic factors of patients with advanced non-Hodgkin's lymphoma treated with VEPA or VEPA-M.
M Shimoyama, K Ota, M Kikuchi, K Yunoki, S Konda, K Takatsuki, ...
Journal of Clinical Oncology 6 (1), 128-141, 1988
1471988
The role of short-chain fatty acid on blood pressure regulation
J Miyamoto, M Kasubuchi, A Nakajima, J Irie, H Itoh, I Kimura
Current Opinion in Nephrology and Hypertension 25 (5), 379-383, 2016
1332016
Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice
J Miyamoto, K Watanabe, S Taira, M Kasubuchi, X Li, J Irie, H Itoh, ...
PLoS One 13 (4), e0196579, 2018
1242018
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